Use of natural AhR ligands as potential therapeutic modalities against inflammatory disorders

Functional Characterization and Gene Expression Analysis of CD4+CD25+ Regulatory T Cells Generated in Mice Treated with 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

(2014) N. B. Marshall et al.   JOURNAL OF IMMUNOLOGY

Quercetin, Resveratrol, and Curcumin Are Indirect Activators of the Aryl Hydrocarbon Receptor (AHR)

(2012) Afshin Mohammadi-Bardbori et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The Aryl Hydrocarbon Receptor Complex and the Control of Gene Expression

(2012) Timothy V. Beischlag et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Quercetin decreases inflammatory response and increases insulin action in skeletal muscle of ob/ob mice and in L6 myotubes

(2012) Gabriel F. Anhê et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Role of resveratrol-induced CD11b+ Gr-1+ myeloid derived suppressor cells (MDSCs) in the reduction of CXCR3+ T cells and amelioration of chronic colitis in IL-10−/− mice

(2011) Udai P. Singh et al.   BRAIN BEHAVIOR AND IMMUNITY

Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients

(2011) Pál Brasnyó et al.   BRITISH JOURNAL OF NUTRITION

Endogenous and Exogenous Ligands of Aryl Hydrocarbon Receptor: Current State of Art

(2011) Lucie Stejskalova et al.   CURRENT DRUG METABOLISM

Anti-inflammatory Effect of Resveratrol and Polydatin by In Vitro IL-17 Modulation

(2011) Giulia Lanzilli et al.   INFLAMMATION

Aryl hydrocarbon receptor-dependent induction of apoptosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin in cerebellar granule cells from mouse

(2011) Francisco J. Sánchez-Martín et al.   JOURNAL OF NEUROCHEMISTRY

Resveratrol has salutary effects on mucociliary transport and inflammation in sinonasal epithelium

(2011) Nathan S. Alexander et al.   LARYNGOSCOPE

Activation of Aryl Hydrocarbon Receptor (AhR) Leads to Reciprocal Epigenetic Regulation of FoxP3 and IL-17 Expression and Amelioration of Experimental Colitis

(2011) Narendra P. Singh et al.   PLoS One

Suppression of WIF-1 through promoter hypermethylation causes accelerated proliferation of the aryl hydrocarbon receptor (AHR) overexpressing MCF10AT1 breast cancer cells

(2011) Dalei Wu et al.   TOXICOLOGY

Plant polyphenols differentially modulate inflammatory responses of human keratinocytes by interfering with activation of transcription factors NFκB and AhR and EGFR–ERK pathway

(2011) Alla I. Potapovich et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Curcumin in Cancer Chemoprevention: Molecular Targets, Pharmacokinetics, Bioavailability, and Clinical Trials

(2010) Adeeb Shehzad et al.   ARCHIV DER PHARMAZIE

Clinical Pharmacology of Resveratrol and Its Metabolites in Colorectal Cancer Patients

(2010) K. R. Patel et al.   CANCER RESEARCH

Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-κB inhibition

(2010) Se-Woong Oh et al.   JOURNAL OF ETHNOPHARMACOLOGY

Resveratrol Prevents Epigenetic Silencing of BRCA-1 by the Aromatic Hydrocarbon Receptor in Human Breast Cancer Cells

(2010) Andreas J. Papoutsis et al.   JOURNAL OF NUTRITION

Indole-3-Carbinol Triggers Aryl Hydrocarbon Receptor-dependent Estrogen Receptor (ER)α Protein Degradation in Breast Cancer Cells Disrupting an ERα-GATA3 Transcriptional Cross-Regulatory Loop

(2010) Crystal N. Marconett et al.   MOLECULAR BIOLOGY OF THE CELL

Resveratrol (3,5,4′-trihydroxystilbene) protects pregnant mother and fetus from the immunotoxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin

(2010) Narendra P. Singh et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Role of Epigenetic Mechanisms in Differential Regulation of the Dioxin-Inducible Human CYP1A1 and CYP1B1 Genes

(2010) S. R. Beedanagari et al.   MOLECULAR PHARMACOLOGY

Aryl Hydrocarbon Receptor Activation by TCDD Reduces Inflammation Associated with Crohn's Disease

(2010) Jenna M. Benson et al.   TOXICOLOGICAL SCIENCES

Differential effects of indirubin and 2,3,7,8-tetrachlorodibenzo-p-dioxin on the aryl hydrocarbon receptor (AhR) signalling in liver progenitor cells

(2010) Jiřina Procházková et al.   TOXICOLOGY

Cancer Prevention and Treatment with Resveratrol: From Rodent Studies to Clinical Trials

(2009) A. Bishayee   Cancer Prevention Research

Relevance of the aryl hydrocarbon receptor (AhR) for clinical toxicology

(2009) Tracey D. Bradshaw et al.   CLINICAL TOXICOLOGY

Quercetin blocks caveolae-dependent pro-inflammatory responses induced by co-planar PCBs

(2009) Yean Jung Choi et al.   ENVIRONMENT INTERNATIONAL

3,3′-diindolylmethane attenuates colonic inflammation and tumorigenesis in mice

(2009) Yoon Hee Kim et al.   INFLAMMATORY BOWEL DISEASES

Constitutively active aryl hydrocarbon receptor expressed in T cells increases immunization-induced IFN-  production in mice but does not suppress Th2-cytokine production or antibody production

(2009) K. Nohara et al.   INTERNATIONAL IMMUNOLOGY

Expression of constitutively-active aryl hydrocarbon receptor in T-cells enhances the down-regulation of CD62L, but does not alter expression of CD25 or suppress the allogeneic CTL response

(2009) Castle J. Funatake et al.   Journal of Immunotoxicology

Antagonism of Aryl Hydrocarbon Receptor Signaling by 6,2',4'-Trimethoxyflavone

(2009) I. A. Murray et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Resveratrol (Trans-3,5,4'-trihydroxystilbene) Induces Silent Mating Type Information Regulation-1 and Down-Regulates Nuclear Transcription Factor- B Activation to Abrogate Dextran Sulfate Sodium-Induced Colitis

(2009) U. P. Singh et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Resveratrol bioavailability and toxicity in humans

(2009) Charles-Henry Cottart et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Indigowood root extract protects hematopoietic cells, reduces tissue damage and modulates inflammatory cytokines after total-body irradiation: Does Indirubin play a role in radioprotection?

(2009) Weir Chiang You et al.   PHYTOMEDICINE

Curcumin, resveratrol and flavonoids as anti-inflammatory, cyto- and DNA-protective dietary compounds

(2009) Kavita Bisht et al.   TOXICOLOGY

The aryl hydrocarbon receptor in immunity

(2009) Charlotte Esser et al.   TRENDS IN IMMUNOLOGY

Biological functions of the arylhydrocarbon receptor: Beyond induction of cytochrome P450s—Introduction to this special issue

(2008) Fumio Matsumura et al.   BIOCHEMICAL PHARMACOLOGY

The immune phenotype of AhR null mouse mutants: Not a simple mirror of xenobiotic receptor over-activation

(2008) Charlotte Esser   BIOCHEMICAL PHARMACOLOGY

AHR-mediated immunomodulation: The role of altered gene transcription

(2008) Nancy I. Kerkvliet   BIOCHEMICAL PHARMACOLOGY

The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways

(2008) Alvaro Puga et al.   BIOCHEMICAL PHARMACOLOGY

Single-Dose Pharmacokinetics and Tolerability of Absorption-Enhanced 3,3'-Diindolylmethane in Healthy Subjects

(2008) G. A. Reed et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Pharmacokinetics of Curcumin Conjugate Metabolites in Healthy Human Subjects

(2008) S. K. Vareed et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Cancer chemotherapy with indole-3-carbinol, bis(3′-indolyl)methane and synthetic analogs

(2008) Stephen Safe et al.   CANCER LETTERS

A New Gene for Auxin Synthesis

(2008) Klaus Palme et al.   CELL

The aryl hydrocarbon receptor: a regulator of Th17 and Treg cell development in disease

(2008) Peggy P Ho et al.   CELL RESEARCH

Curcumin: From ancient medicine to current clinical trials

(2008) H. Hatcher et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Targeting of the immune system in systemic lupus erythematosus

(2008) Meera Ramanujam et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

NF-κB Signaling Pathway and Its Therapeutic Implications in Human Diseases

(2008) Fazlul H. Sarkar et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Dietary resveratrol alters lipid metabolism-related gene expression of mice on an atherogenic diet

(2008) Jiyun Ahn et al.   JOURNAL OF HEPATOLOGY

Targeting of Aryl Hydrocarbon Receptor-Mediated Activation of Cyclooxygenase-2 Expression by the Indole-3-Carbinol Metabolite 3,3′-Diindolylmethane in Breast Cancer Cells

(2008) Stephanie C. Degner et al.   JOURNAL OF NUTRITION

Nanoencapsulation of quercetin enhances its dietary efficacy in combating arsenic-induced oxidative damage in liver and brain of rats

(2008) Aparajita Ghosh et al.   LIFE SCIENCES

Curcumin in cancer management: Recent results of analogue design and clinical studies and desirable future research

(2008) William P. Steward et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Resveratrol addiction: To die or not to die

(2008) Mehdi Shakibaei et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

(2008) Francisco J. Quintana et al.   NATURE

Determination and pharmacokinetic study of indirubin in rat plasma by high-performance liquid chromatography

(2008) X.Y. Deng et al.   PHYTOMEDICINE

3,3′-Diindolylmethane stimulates murine immune function in vitro and in vivo

(2007) L XUE et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY