Article
Nutrition & Dietetics
Sehoon Park, Soojin Lee, Yaerim Kim, Semin Cho, Kwangsoo Kim, Yong Chul Kim, Seung Seok Han, Hajeong Lee, Jung Pyo Lee, Kwon Wook Joo, Chun Soo Lim, Yon Su Kim, Dong Ki Kim
Summary: This study shows that a high blood homocysteine level causally decreases eGFR, while high folate levels are associated with an increase in eGFR. Future trials may reveal the importance of homocysteine-lowering interventions for the prevention of kidney function impairment.
Article
Medicine, General & Internal
Ram K. Chandyo, Ingrid Kvestad, Manjeswori Ulak, Suman Ranjitkar, Mari Hysing, Merina Shrestha, Catherine Schwinger, Adrian McCann, Per M. Ueland, Sudha Basnet, Laxman Shrestha, Tor A. Strand
Summary: This study investigated the effect of vitamin B12 supplementation from early pregnancy until 6 months postpartum on infant growth and neurodevelopment. The results showed that supplementation did not improve these outcomes. The findings support the current WHO recommendations of no routine vitamin B12 supplementation during pregnancy.
Review
Biochemistry & Molecular Biology
Lyazzat Kaldygulova, Talshyn Ukybassova, Gulzhanat Aimagambetova, Andrey Gaiday, Akylbek Tussupkaliyev
Summary: The rationale and importance of folic acid supplementation during pregnancy for preventing fetal congenital defects are widely accepted. Adequate folate levels can reduce the risk of spontaneous abortions and support normal placental blood flow, promoting appropriate fetal growth. Additionally, there is emerging evidence that long-term folic acid supplementation can effectively prevent preeclampsia, a complication unique to humans during pregnancy that contributes to worldwide maternal and perinatal mortality. Folate supplementation helps to decrease elevated levels of homocysteine, which is associated with the risk of preeclampsia.
Article
Nutrition & Dietetics
Mengru Li, Xiaotian Chen, Yi Zhang, Hongyan Chen, Dingmei Wang, Chao Cao, Yuan Jiang, Xiangyuan Huang, Yalan Dou, Yin Wang, Xiaojing Ma, Wei Sheng, Weili Yan, Guoying Huang
Summary: The study found that most pregnancy-preparing couples failed to achieve the optimal RBC folate status recommended by the WHO, calling for attention to the insufficiency status of folate.
JOURNAL OF NUTRITION
(2022)
Article
Multidisciplinary Sciences
Femke Hannes, Kevin Moon, Regina Moench Pfanner
Summary: Poor diet leads to nutrient deficiency, especially among male migrant construction workers in Singapore. However, consuming fortified rice can significantly improve their nutritional status and health.
Article
Nutrition & Dietetics
Igor Pravst, Ziva Lavrisa, Masa Hribar, Hristo Hristov, Naska Kvarantan, Barbara Korousic Seljak, Matej Gregoric, Urska Blaznik, Nadan Gregoric, Katja Zaletel, Adrijana Oblak, Josko Osredkar, Katja Zmitek, Anita Kusar
Summary: Folate deficiency is common in Slovenia, with low folate intake observed in various age groups. Public health strategies are needed to promote the consumption of folate-rich foods and supplementation with folic acid may be necessary in specific vulnerable populations.
Article
Biochemistry & Molecular Biology
Aida Corrillero Bravo, Maria Nieves Ligero Aguilera, Nahuel R. Marziali, Lennart Moritz, Victoria Wingert, Katharina Klotz, Anke Schumann, Sarah C. Gruenert, Ute Spiekerkoetter, Urs Berger, Ann-Kathrin Lederer, Roman Huber, Luciana Hannibal
Summary: S-adenosylmethionine (SAM) is essential for methyl transfer reactions. SAM is produced de novo via the methionine cycle. The demethylation of SAM produces S-adenosylhomocysteine (SAH), an inhibitor of methyltransferases. Measurement of SAM and SAH in plasma is valuable for diagnosing inborn errors of metabolism and assessing methyl group homeostasis.
Article
Cardiac & Cardiovascular Systems
Tetiana Kovalchuk, Oksana Boyarchuk
Summary: This study aimed to investigate the levels of B vitamins deficiency and homocysteine in children with vasovagal syncope and analyze their correlation with syncope. The results suggested that pyridoxine, folate, cobalamin, and homocysteine may be involved in the pathogenesis of vasovagal syncope.
CARDIOLOGY IN THE YOUNG
(2022)
Article
Multidisciplinary Sciences
Xiaorui Chen, Xiaowen Huang, Diao Jie, Caifang Zheng, Xiliang Wang, Bowen Zhang, Weihao Shao, Gaili Wang, Weidong Zhang
Summary: This study established an artificial neural network (ANN) model to predict the efficacy of folic acid therapy to Hyperhomocysteinemia by incorporating explained variance genetic risk score (EV-GRS), which showed higher predictive power compared to logistic regression (LR) model. The ANN model exhibited higher accuracy, AUC, and Youden's index, suggesting its potential clinical application for individualized therapeutic planning.
SCIENTIFIC REPORTS
(2021)
Article
Neurosciences
Yongjie Chen, Yue Du, Zhuoyu Sun, Qian Liu, Changqing Sun, Hongyan Lin, Mengdi Jin, Jingzhu Fu, Fei Ma, Wen Li, Huan Liu, Xumei Zhang, Guangshun Wang, Guowei Huang
Summary: The study found interactions between handgrip strength and serum folate and homocysteine levels on cognitive function. Subjects with strong handgrip strength and sufficient folate levels had the best cognitive function.
JOURNAL OF ALZHEIMERS DISEASE
(2021)
Article
Nutrition & Dietetics
Rolland Mutumba, Hannah Pesu, Joseph Mbabazi, Eva Greibe, Mette F. Olsen, Andre Briend, Christian Molgaard, Christian Ritz, Nicolette Nabukeera-Barungi, Ezekiel Mupere, Suzanne Filteau, Henrik Friis, Benedikte Grenov
Summary: This study assessed the correlates of iron, cobalamin, folate, and vitamin A biomarkers in stunted children in eastern Uganda. The results showed that these children have deficiencies in iron, cobalamin, and vitamin A. Therefore, interventions addressing stunting should also target these micronutrient deficiencies.
Article
Multidisciplinary Sciences
Saad Al-Fawaeir, Ibrahim Al-Odat
Summary: The study found a significant association between metformin intake and vitamin B12 deficiency in patients with type 2 diabetes mellitus. Regular monitoring of serum vitamin B12 levels is necessary for patients taking metformin.
Article
Multidisciplinary Sciences
Carlos Alessandro Fuzo, Fabio da Veiga Ued, Sofia Moco, Ornella Cominetti, Sylviane Metairon, Solenn Pruvost, Aline Charpagne, Jerome Carayol, Raul Torrieri, Wilson Araujo Silva Jr, Patrick Descombes, Jim Kaput, Jacqueline Pontes Monteiro
Summary: Vitamin B12 levels in Brazilian children and adolescents are influenced by genetic ancestry, with a polygenic risk score explaining nearly 50% of the variation.
SCIENTIFIC REPORTS
(2021)
Article
Nutrition & Dietetics
Carmen Morais-Moreno, Ana M. Montero-Bravo, Ana M. Puga, Ma de Lourdes Samaniego-Vaesken, Mar Ruperto, Rocio Marco Mendez, Alvaro Vicente-Arche, Gregorio Varela-Moreiras, Teresa Partearroyo
Summary: Noise-induced hearing loss is a common and preventable occupational disease. Aviation pilots, who spend a lot of time exposed to noise pollution, are particularly vulnerable. This study found that flight hours, serum folate, and homocysteine levels were significantly related to hearing loss in pilots.
Article
Nutrition & Dietetics
Audrey St-Laurent, Anne-Sophie Plante, Simone Lemieux, Julie Robitaille, Amanda J. MacFarlane, Anne-Sophie Morisset
Summary: This study investigated the folate and vitamin B12 levels in 79 French-Canadian pregnant women at different stages of pregnancy. It was found that the intake of folate and vitamin B12 in the diet was associated with the concentration of these biomarkers in the blood. The serum total folate concentrations were generally high, while the vitamin B12 concentrations were influenced by the body mass index of the pregnant women.
JOURNAL OF NUTRITION
(2023)
Article
Nutrition & Dietetics
Carmen Perez-Rodrigo, Marta Gianzo Citores, Gotzone Hervas Barbara, Fatima Ruiz-Litago, Luis Casis Saenz, Victoria Arija, Ana M. Lopez-Sobaler, Emilio Martinez de Victoria, Rosa M. Ortega, Teresa Partearroyo, Joan Quiles-Izquierdo, Lourdes Ribas-Barba, Amelia Rodriguez-Martin, Gemma Salvador Castell, Josep A. Tur, Gregorio Varela-Moreiras, Lluis Serra-Majem, Javier Aranceta-Bartrina
Summary: The study identified different patterns of change in lifestyles during confinement, suggesting the need to provide tailored support and advice to different population groups.
Article
Nutrition & Dietetics
Estela Maldonado, Elena Martinez-Sanz, Teresa Partearroyo, Gregorio Varela-Moreiras, Juliana Perez-Miguelsanz
Summary: This study demonstrates that maternal folate deficiency can lead to various craniofacial malformations in embryos, with a higher risk of affecting cleft palate and nasal region development. The results show a significant reduction in the number of fetuses over time under FAD diet, along with various severe abnormalities, with nasal region dysmorphologies being the most frequent.
Article
Nutrition & Dietetics
Catalina Ballestero-Fernandez, Gregorio Varela-Moreiras, Natalia Ubeda, Elena Alonso-Aperte
Summary: Individuals with celiac disease following a long-term gluten-free diet have deficiencies in several key nutrients, including folates, vitamin D, calcium, vitamin E, iodine, and iron. Some celiac patients may be more at risk for osteopenia and osteoporosis. However, the overall nutritional status and dietary patterns of celiac individuals did not significantly differ from those of healthy volunteers in the study population. Regular monitoring and assessment of nutrient levels should be conducted in the celiac population.
Article
Nutrition & Dietetics
Casandra Madrigal, Maria Jose Soto-Mendez, Angela Hernandez-Ruiz, Teresa Valero, Federico Lara Villoslada, Rosaura Leis, Emilio Martinez de Victoria, Jose Manuel Moreno, Rosa M. Ortega, Maria Dolores Ruiz-Lopez, Gregorio Varela-Moreiras, Angel Gil
Summary: This study focused on the protein intake in children aged 1 to <10 years old in Spain and found that their protein intake exceeded European and international recommendations, with main sources being milk and dairy products and meat. Future research should explore the long-term effects of dietary protein in early childhood on growth and body composition.
Article
Nutrition & Dietetics
Juliana Perez-Miguelsanz, Vanesa Jimenez-Ortega, Pilar Cano-Barquilla, Marta Garaulet, Ana Esquifino, Gregorio Varela-Moreiras, Pilar Fernandez-Mateos
Summary: Epicardial adipose tissue (EAT) originates early in embryonic development and goes through five stages including angiogenesis and the appearance of adipocytes. Factors such as maternal health and nutrition may influence the early development of EAT, which has clinical implications for cardiovascular and metabolic diseases.
Review
Nutrition & Dietetics
Ana M. Puga, Mar Ruperto, M. de Lourdes Samaniego-Vaesken, Ana Montero-Bravo, Teresa Partearroyo, Gregorio Varela-Moreiras
Summary: Cognitive impairment and Alzheimer's Disease are major public health problems, with folic acid deficiency being linked to neurocognitive dysfunctions. There is controversy surrounding the efficacy of vitamin supplementation in these pathologies, but research supports potential benefits for Alzheimer's Disease and cognitive impairment, though further studies are needed for confirmation.
Article
Nutrition & Dietetics
Marina Redruello-Requejo, Maria Gonzalez-Rodriguez, Ma de Lourdes Samaniego-Vaesken, Ana Montero-Bravo, Teresa Partearroyo, Gregorio Varela-Moreiras
Summary: The presence and consumption of LNCS in foods and beverages consumed by a representative sample of the Spanish adult population were identified in this study. LNCS were found in 4.5% of foods and 22.3% of beverages, with the highest consumption in non-alcoholic beverages, sugars and sweets, and dairy products. A variety of LNCS were consumed, with differences in prevalence among various food and beverage categories.
Article
Family Studies
Joana Roige-Castellvi, Michelle M. Murphy, Nuria Voltas, Pol Sole-Navais, Pere Cavalle-Busquets, Joan Fernandez-Ballart, Monica Ballesteros, Josefa Canals-Sans
Summary: Prenatal smoke exposure is negatively associated with behavioral development in children, particularly affecting scores related to affective problems, while no significant association was found with externalizing problems.
JOURNAL OF CHILD AND FAMILY STUDIES
(2021)
Article
Cardiac & Cardiovascular Systems
Maria Rubin-Garcia, Facundo Vitelli-Storelli, Estefania Toledo, Sara Castro-Barquero, Anna Tresserra-Rimbau, Miguel Angel Martinez-Gonzalez, Jordi Salas-Salvado, Dolores Corella, Alvaro Hernaez, J. Alfredo Martinez, Angel M. Alonso-Gomez, Julia Warnberg, Jesus Vioque, Dora Romaguera, Jose Lopez-Miranda, Ramon Estruch, M. Rosa Bernal-Lopez, Jose Lapetra, Luis Serra-Majem, Aurora Bueno-Cavanillas, Josep A. Tur, Laura Alvarez-Alvarez, Xavier Pinto, Jose J. Gaforio, Pilar Matia-Martin, Josep Vidal, Clotilde Vazquez, Lidia Daimiel, Emili Ros, Alfredo Gea, Jose Maria Manzanares, Jose V. Sorli, Helmut Schroder, Itziar Abete, Lucas Tojal-Sierra, Edelys Crespo-Oliva, Andres Gonzalez-Botella, Elena Rayo, Antonio Garcia-Rios, Ana Maria Gomez-Perez, Jose Manuel Santos-Lozano, Rafael Bartolome Resano, Michelle M. Murphy, Carolina Ortega-Azorin, Casimira Medrano, Maria Angeles Zulet, Carolina Sorto-Sanchez, Nancy Babio, Montserrat Fito, Rosa Maria Lamuela-Raventos, Vicente Martin-Sanchez
Summary: This study aimed to assess the association between intake of different classes of polyphenols and cardiovascular risk scores. The results showed that intake of polyphenols, except phenolic acids, was associated with a lower cardiovascular risk, especially among women.
REVISTA ESPANOLA DE CARDIOLOGIA
(2022)
Article
Nutrition & Dietetics
Maria Gonzalez-Rodriguez, Marina Redruello-Requejo, Maria De Lourdes Samaniego-Vaesken, Ana Montero-Bravo, Ana M. Puga, Teresa Partearroyo, Gregorio Varela-Moreiras
Summary: The study found that 4.1% of foods and 16.7% of beverages consumed by the Portuguese adult population contained low and no-calorie sweeteners (LNCS). The main sources of LNCS were non-alcoholic beverages, milk and dairy products, appetizers, candies, meat products, etc.
Article
Nutrition & Dietetics
Marina Redruello-Requejo, Maria de Lourdes Samaniego-Vaesken, Teresa Partearroyo, Paula Rodriguez-Alonso, Maria Jose Soto-Mendez, Angela Hernandez-Ruiz, Federico Lara Villoslada, Rosaura Leis, Emilio Martinez de Victoria, Jose Manuel Moreno, Rosa M. Ortega, Maria Dolores Ruiz-Lopez, Angel Gil, Gregorio Varela-Moreiras
Summary: The study evaluated the sugar intake levels and dietary sources in Spanish children consuming different types of milk. It found that younger children had higher added sugar contributions to their total energy intake and lower adherence to recommendations. The main food sources of intrinsic sugars were milk and dairy products, fruits, vegetables, and cereals, while milk and dairy products, sugars and sweets, bakery products, and cereals were the main sources of added sugars. The results emphasize the importance of monitoring sugar consumption in infants and the need for simplified recommendations and labeling of products.
Review
Nutrition & Dietetics
Ana M. Puga, Maria de Lourdes Samaniego-Vaesken, Ana Montero-Bravo, Mar Ruperto, Teresa Partearroyo, Gregorio Varela-Moreiras
Summary: Gut microbiota plays a crucial role in human health, and both diet and iron supplementation have an impact on it. Iron supplementation can potentially harm the gut microbiota, therefore it should be used with caution and recommended only to individuals with confirmed iron deficiency or iron-deficiency anemia. Further population studies are needed to confirm these findings.
Article
Nutrition & Dietetics
Casandra Madrigal, Maria Jose Soto-Mendez, Angela Hernandez-Ruiz, Maria Dolores Ruiz-Lopez, Maria De Lourdes Samaniego-Vaesken, Teresa Partearroyo, Gregorio Varela-Moreiras, Angel Gil
Summary: This study evaluated the nutrient intake of Spanish children for zinc, selenium, vitamin A, C, and E, finding significant differences in intake between different subpopulations. The majority of children had vitamin A and E intakes below the recommended levels.
Article
Nutrition & Dietetics
Carmen Morais-Moreno, Ana M. Montero-Bravo, Ana M. Puga, Ma de Lourdes Samaniego-Vaesken, Mar Ruperto, Rocio Marco Mendez, Alvaro Vicente-Arche, Gregorio Varela-Moreiras, Teresa Partearroyo
Summary: Noise-induced hearing loss is a common and preventable occupational disease. Aviation pilots, who spend a lot of time exposed to noise pollution, are particularly vulnerable. This study found that flight hours, serum folate, and homocysteine levels were significantly related to hearing loss in pilots.
Article
Environmental Sciences
Rocio de la Iglesia, Angela Garcia-Gonzalez, Maria Achon, Gregorio Varela-Moreiras, Elena Alonso Aperte
Summary: The study analyzed purchase data of fish, seafood, and fish products during the lockdown in Spain and found a 45% increase in the purchase of all types of these products, with retirees showing the highest increment.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
