Article
Chemistry, Analytical
Lin Sun, Lei Chen, Bingyu Zhu, Mi Gong, Hong Chen, Ziwei Tang, Xiayu Zhou, Jinquan Liu, Deshuai Zhen, Le Li
Summary: An ultra-sensitive method for detection of UO22+ was developed based on MoS2 nanosheet and the principle of entropy-driven amplification. This method has been successfully applied to the detection of UO22+ in water samples and has shown certain potential in the prevention and control of environmental pollution.
MICROCHEMICAL JOURNAL
(2022)
Article
Spectroscopy
Qinghua Hu, Wenfeng Zhang, Qiang Yin, Yuyuan Wang, Hongqing Wang
Summary: A conjugated fluorescent polymer sensor P2 based on amidoxime groups and polyfluorene was designed and prepared for trace uranyl ion detection in an aqueous medium. The sensor showed good selectivity and sensitivity, with significant application potential for environmental uranyl ion detection.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Analytical
Ming Zheng, Qiang Yin, Dongyuan Wang, Zixuan Zhao, Qinghua Hu, Hongqing Wang
Summary: A novel triphenylamine-based fluorescent sensor (USC-001) has been designed and prepared for the detection of uranyl ions in acidic and high water ratio environments, showing good selectivity and potential applications. The sensor has been successfully utilized for the detection of uranyl ions in actual water samples and biological cells.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Changming Cheng, Hao Yang, Ying Huang, Jun Wang, Mei Gu, Yi Liu, Ning Wang, Jing Wang, Sheng Hu, Ruijie Deng
Summary: In this study, a novel nanosystem based on DNAzyme and graphene oxide (GO) was proposed for sensitive detection of uranyl ion (UO22+) in environmental water. The nanosystem achieved turn-on fluorescent sensing of UO22+ by combining the selectivity of DNAzyme towards UO22+, the fluorescence quenching ability of GO, and the affinity of GO towards DNAs with different structures. The proposed nanosystem showed excellent analytical performance with a wide dynamic response range, low detection limit, and good selectivity, making it highly promising for environmental monitoring.
MICROCHEMICAL JOURNAL
(2022)
Article
Nanoscience & Nanotechnology
Xuemeng Yang, Shufang Lv, Tianci Li, Shuai Hao, Hongnan Zhu, Yan Cheng, Shuaijie Li, Hongzan Song
Summary: In this study, a stretchable, dual thermo-responsive and strain-responsive ionogel was synthesized using a one-step photopolymerization method. The resulting ionogel exhibited high stretchability, high ionic conductivity, and good temperature tolerance. It also showed a tunable phase-transition temperature and reversible color/transparency switching. The ionogel-based temperature monitors, smart windows, and strain sensors demonstrated excellent designability, programmability, temperature modulation ability, and thermal responsiveness. This approach holds great promise for the development of multifunctional stimuli-responsive materials.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Optics
Na Lin, Ran Tao, Zhijiang Chen, Qifa Pan, Zhihao Zhu, Bo Gao, Wensheng Ren
Summary: A new fluorescent film sensor has been designed and fabricated for the detection of UO22+, with a low detection limit of 32 nM. The sensor shows higher selectivity towards UO22+ compared to other metal ions, and can be used as a convenient tool for UO22+ detection.
JOURNAL OF LUMINESCENCE
(2022)
Article
Polymer Science
Mahuya Kar, Mahammad Anas, Arpana Singh, Ambuz Basak, Prosenjit Sen, Tarun K. Mandal
Summary: This manuscript describes the attachment of alkylvinylimidazolium-based poly(ionic liquid) (PIL) to the imide positions of perylene bisimide (PBI) to introduce stimuli-responsiveness and to make the conjugate soluble in water and water-based mixed solvents with the possibilities of using them as a probe for imaging and diagnostics in biomedical domain. The conjugate formed self-aggregates into vesicles in water and methanol/water mixture, and it responds to anions by forming insoluble spherical aggregates. The conjugate also exhibits upper critical solution temperature (UCST)-type phase transition and changes in UV-vis and fluorescence spectra upon heating or addition of anions.
EUROPEAN POLYMER JOURNAL
(2022)
Article
Materials Science, Multidisciplinary
Min Shen, Tingting Pan, Juewei Ning, Jiayan Shi, Hongtian Liu, Yanqing Tian
Summary: A K+ fluorescent sensor P2 was fabricated based on thermoresponsive poly(N-isopropylacrylamide) and small molecule K+ fluorescent sensor KS, showing high selectivity and sensitivity to K+. P2 changed its size at a specific temperature range and responded to K+, suitable for extracellular K+ analysis.
MATERIALS TODAY COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Yufei Lei, Yujie Li, Chen Liu, Liqiong He, Qian Li, Lifu Liao, Xilin Xiao
Summary: This study proposes a convenient and portable smartphone-assisted method for the colorimetric detection of uranyl ions in aqueous solutions. The method utilizes rifampicin and Br-PADAP as chromogenic agents, which undergo color changes upon reaction with UO22+. Digital images captured by a smartphone are analyzed using the built-in application Detect to estimate the concentration of uranyl ions. UV-vis spectroscopy is also employed for more precise laboratory-level detection. The method has been successfully used to analyze real samples including soil around uranium mines.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Tiantian Feng, Yihui Yuan, Shilei Zhao, Lijuan Feng, Bingjie Yan, Meng Cao, Jiacheng Zhang, Wenyan Sun, Ke Lin, Ning Wang
Summary: The detection of environmental uranyl is a topic of increasing interest. This study presents a detection strategy based on the unique uranyl-triggered photocleavage property, using fluorescent-molecule-labelled protein fragments to achieve high selectivity and a low detection limit of 24 pM for uranyl detection. The method shows high reliability and stability, making it promising for practical applications in diverse environments.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Review
Chemistry, Inorganic & Nuclear
Min Qiao, Liping Ding, Fengting Lv
Summary: This paper introduces the development of fluorescent sensors for metal ions based on fluorescent ensembles, particularly focusing on the strategies for obtaining these sensors and methods for adjusting their sensing behaviors.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Spectroscopy
Mioara Murariu, Lenuta Stroea
Summary: New fluorescent polymeric sensors containing in situ photogenerated gold nanoparticles (Au NPs) and fluorescein-based copolymers are reported. They are tested as efficient fluorescent chemosensors for the sensitive detection of toxic divalent metal ions. The best results are recorded for uranyl (4 x 10-6 M) and copper ions (16 x 10-6 M), respectively. The investigated hybrid materials have lower detection limits and the fluorescence quenching mainly occurs by a dynamic process.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Spectroscopy
Lianshun Zhang, Mengqing Jia, Xi Wang, Lei Gao, Bo Zhang, Lei Wang, Jinming Kong, Lianzhi Li
Summary: The sensitive and selective detection of uranyl ion (UO22+) is crucial for environmental and biological samples due to its high health risks. Researchers have developed a novel fluorescence sensor, D-P5, which exhibits high selectivity and sensitivity to UO22+ over 27 different metal ions.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Biophysics
Jie Chi, Yanyan Song, Liang Feng
Summary: Ratiometric fluorescent sensors with built-in self-calibration characteristics can suppress interference and exhibit higher sensitivity and more obvious visual detection in qualitative and quantitative analysis. In this study, a ratiometric fluorescence probe based on fluorescent/colorimetric dual-mode method was constructed for the accurate determination of arginine. The practicality of the sensor was successfully validated by quantitative detection of arginine in human serum. Furthermore, paper-based sensors were developed for arginine detection, providing a convenient and efficient method for on-site detection.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Physical
Jundan Tang, Lihua Shen, Kunpeng Zhao, Jiaming Peng, Qili Chen, Chunxia Yu, Yuangang Li, Azhar Abbas, Shan Wang, Zhifang Liu
Summary: A nanocomposite-based sensor using Ag@sulfur nanosheets has been developed for ultrasensitive detection of NH3 in gas at room temperature. By introducing Ag nanoparticles, the sensor shows a high response rate and linear response to NH3 in the range of 3-70 ppt, with fast response and recovery time.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).