4.2 Article

Feasibility of the Cut-and-Push Method for Removing Large-Caliber Soft Percutaneous Endoscopic Gastrostomy Devices

Journal

NUTRITION IN CLINICAL PRACTICE
Volume 28, Issue 4, Pages 490-492

Publisher

WILEY
DOI: 10.1177/0884533613486933

Keywords

enteral nutrition; gastrostomy

Ask authors/readers for more resources

Introduction: Percutaneous endoscopic gastrostomy (PEG) is the method of choice for long-term nutrition in patients with longstanding eating difficulties due to pathological entities that impair swallowing. The feeding catheters are designed to be removed by external traction or by endoscopy. Aim: To evaluate the feasibility of the cut-and-push method as a possible safe alternative to the pullout method for removal of soft PEG devices with a large caliber. Methods: Patients with 20 French (Fr) or larger soft PEG system were enrolled for PEG removal by the cut-and-push technique. The replacement catheters were 2 Fr larger than the original ones. Patients were observed at 24 and 72 hours via home nursing care and then weekly for 1 month for signs of intestinal obstruction, tube leakage, or blockage. Results: Seventy-nine patients (52 men; mean age 67 years) underwent the procedure: 42 due to leakage and 37 due to blockage. Mean time before tube removal was 4.8 months (range, 3-8). PEG devices were 20 Fr and 24 Fr in 57 (72.2%) and 22 (27.8%) cases, respectively. Collection of the inner component from stool was reported within 48 hours in 63 cases (80%). No cases of intestinal obstruction or other severe adverse events due to the inner component being eliminated throughout the intestine were observed in any patient during the study. Conclusions: The cut-and-push method employed for removal of a soft PEG tube with a large caliber seems to be safe and can be performed when removal by external traction may determine the occurrence of peristomal complications or jeopardize PEG replacement.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.2
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Gastroenterology & Hepatology

Epidemiological trends and trajectories of MAFLD-associated hepatocellular carcinoma 2002-2033: the ITA.LI.CA database

Alessandro Vitale, Gianluca Svegliati-Baroni, Alessio Ortolani, Monica Cucco, Giulio Dalla Riva, Edoardo G. Giannini, Fabio Piscaglia, Gianludovico Rapaccini, Mariella Di Marco, Eugenio Caturelli, Marco Zoli, Rodolfo Sacco, Giuseppe Cabibbo, Fabio Marra, Andrea Mega, Filomena Morisco, Antonio Gasbarrini, Francesco Giuseppe Foschi, Gabriele Missale, Alberto Masotto, Gerardo Nardone, Giovanni Raimondo, Francesco Azzaroli, Gianpaolo Vidili, Filippo Oliveri, Filippo Pelizzaro, Rafael Ramirez Morales, Umberto Cillo, Franco Trevisani, Luca Miele, Giulio Marchesini, Fabio Farinati

Summary: This study compared patients with MAFLD and non-MAFLD who had hepatocellular carcinoma (HCC) in Italy. It found that the proportion of MAFLD in HCC patients was increasing over time and is expected to surpass non-MAFLD in the future. Despite a later cancer stage at diagnosis, MAFLD HCC patients had a lower risk of HCC-related death, suggesting reduced cancer aggressiveness.
Article Medicine, General & Internal

The role of antiplatelet therapies on incidence and mortality of hepatocellular carcinoma

Quirino Lai, Nicoletta De Matthaeis, Michele Finotti, Giovanni Galati, Giuseppe Marrone, Fabio Melandro, Filomena Morisco, Daniele Nicolini, Riccardo Pravisani, Edoardo G. Giannini

Summary: This study evaluates the impact of antiplatelet therapy on the incidence and mortality of hepatocellular carcinoma. The results suggest that antiplatelet therapy is associated with a reduced risk of HCC incidence and post-treatment mortality.

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2023)

Review Gastroenterology & Hepatology

Immune checkpoint inhibitors in malignancies after liver transplantation: A systematic review and pooled analysis

Stefano Kayali, Andrea Pasta, Maria Corina Plaz Torres, Ariel Jaffe, Mario Strazzabosco, Simona Marenco, Edoardo G. Giannini

Summary: This systematic review with pooled analysis assessed the safety and efficacy of immune checkpoint inhibitor (ICI) therapy in liver transplant recipients. The results showed that ICI treatment in these patients is associated with a risk of graft rejection and mortality, but some patients had disease control and longer overall survival. More prospective studies are needed to provide accurate data on the safety and efficacy of ICI treatment in this population.

LIVER INTERNATIONAL (2023)

Article Oncology

Role of Etiology in Hepatocellular Carcinoma Patients Treated with Lenvatinib: A Counterfactual Event-Based Mediation Analysis

Rodolfo Sacco, Daryl Ramai, Raffaella Tortora, Giovan Giuseppe di Costanzo, Michela Emma Burlone, Mario Pirisi, Piera Federico, Bruno Daniele, Marianna Silletta, Paolo Gallo, Caterina Cocuzza, Maurizio Russello, Giuseppe Cabibbo, Gabriele Rancatore, Silvia Cesario, Gianluca Masi, Luca Marzi, Andrea Mega, Alessandro Granito, Giulia Pieri, Edoardo G. G. Giannini, Rosa Paolillo, Gennaro Gadaleta-Caldarola, Vincenzo Dadduzio, Guido Giordano, Luca Giacomelli, Simonetta Papa, Matteo Renzulli, Marcello Maida, Michele Ghidini, Mauro Borzio, Antonio Facciorusso

Summary: Hepatocellular carcinoma is the fifth most common cancer worldwide. Lenvatinib has proven to be an effective option for treating advanced diseases. Our study showed that patients with nonviral etiologies have longer survival than those with viral etiology, which is important for clinical decision-making.

CANCERS (2023)

Review Gastroenterology & Hepatology

Safety and efficacy of venous thromboembolism prophylaxis in patients with cirrhosis: A systematic review and meta-analysis

Andrea Pasta, Francesco Calabrese, Sara Labanca, Simona Marenco, Giulia Pieri, Maria Corina Plaz Torres, Nicolas M. Intagliata, Stephen H. Caldwell, Edoardo G. Giannini

Summary: This study aimed to assess the safety and efficacy of venous thromboembolism (VTE) prophylaxis in patients with cirrhosis. The results suggested that the current evidence is insufficient to advise for or against the use of VTE prophylaxis, mainly due to lack of quality and homogeneity of available data. However, the prophylaxis does not appear to be associated with a significant bleeding risk.

LIVER INTERNATIONAL (2023)

Letter Gastroenterology & Hepatology

Letter to the Editor: Objective evaluation of liver steatosis in donor organs-Potential usefulness of noninvasive assessment

Edoardo G. Giannini, Giacomo Borgonovo, Simona Marenco, Manuela Cesaretti

LIVER TRANSPLANTATION (2023)

Letter Hematology

Assessing the Short-Term Prognosis of Patients with Cirrhosis Using the DIC Scores

Andrea Pasta, Francesco Calabrese, Edoardo G. Giannini

THROMBOSIS AND HAEMOSTASIS (2023)

Article Oncology

Can High-Frequency Intraoral Ultrasound Predict Histological Risk Factors in Oral Squamous Cell Carcinoma? A Preliminary Experience

Simone Caprioli, Giorgio-Gregory Giordano, Alessia Pennacchi, Valentina Campagnari, Andrea Iandelli, Giampiero Parrinello, Cristina Conforti, Riccardo Gili, Edoardo Giannini, Elisa Marabotto, Stefano Kayali, Bernardo Bianchi, Giorgio Peretti, Giuseppe Cittadini, Filippo Marchi

Summary: This study evaluates the potential of high-frequency intraoral ultrasonography (IOUS) in predicting histological risk factors in oral cavity squamous cell carcinoma (OSCC). The results show excellent agreement between ultrasonographic and pathological measurements of depth of invasion (DOI), and a significant association between ultrasonographic morphology and adverse histopathological factors. IOUS demonstrates high sensitivity and specificity in predicting Brandwein-Gensler score.

CANCERS (2023)

Editorial Material Oncology

Gastrointestinal Tract Cancers, an Increasing Burden of the Modern Era: Epidemiology and Prevention

Stefano Kayali, Elisa Marabotto, Edoardo Giannini

CANCERS (2023)

Review Pharmacology & Pharmacy

Personalized and Precision Medicine in Asthma and Eosinophilic Esophagitis: The Role of T2 Target Therapy

Diego Bagnasco, Edoardo Vincenzo Savarino, Mona-Rita Yacoub, Fulvio Braido, Maria Giulia Candeliere, Edoardo Giannini, Giovanni Passalacqua, Elisa Marabotto

Summary: Type 2 inflammation plays a crucial role in various diseases, and drugs originally developed for severe asthma have shown potential in treating eosinophilic esophagitis. Promising results from clinical trials suggest that these drugs may also be used in gastroenterology in the future.

PHARMACEUTICS (2023)

Article Gastroenterology & Hepatology

Integrated phenotyping of the anti-cancer immune response in HIV-associated hepatocellular carcinoma

David J. Pinato, Takahiro Kaneko, Antonio D'Alessio, Alejandro Forner, Petros Fessas, Beatriz Minguez, Edoardo G. Giannini, Federica Grillo, Alba Diaz, Francesco A. Mauri, Claudia A. M. Fulgenzi, Alessia Dalla Pria, Robert D. Goldin, Giulia Pieri, Pierluigi Toniutto, Claudio Avellini, Maria Corina Plaz Torres, Ayse U. Akarca, Teresa Marafioti, Sherrie Bhoori, Jose Maria Miro, Mark Bower, Norbert Brau, Vincenzo Mazzaferro

Summary: The aim of this study was to evaluate the impact of HIV infection on the functional characteristics of T cell infiltrate in hepatocellular carcinoma (HCC). Results showed that HIV infection was associated with increased immune exhaustion and higher expression of PD-L1 in tumor tissue. Therefore, prospective testing of immunotherapy in HIV-associated HCC is warranted.

JHEP REPORTS (2023)

Article Rheumatology

Association between esophageal motor disorders and pulmonary involvement in patients affected by systemic sclerosis: a retrospective study

Ylenia Marten Canavesio, Andrea Pasta, Francesco Calabrese, Elisa Alessandri, Maurizio Cutolo, Sabrina Paolino, Carmen Pizzorni, Alberto Sulli, Vincenzo Savarino, Edoardo Giovanni Giannini, Patrizia Zentilin, Giorgia Bodini, Manuele Furnari, Edoardo Savarino, Elisa Marabotto

Summary: This study aims to evaluate the association and prognostic implication between motor esophageal disorders and pulmonary involvement in SSc patients. The study found that the severity of motor esophageal disorders is positively correlated with the severity of pulmonary disease.

RHEUMATOLOGY INTERNATIONAL (2023)

Article Medicine, General & Internal

Looking Beyond What You See: A Rare Cause of Dysphagia

Arshad M. Muhammad, Mohammed F. Farooqi, Mohamed M. Bashir, Aysha S. Aldhaheri, Adnan Agha

Summary: Hypothyroidism is a common endocrine condition with a wide range of symptoms, including dysphagia. The underlying mechanism of dysphagia in hypothyroidism is still unknown, but it is believed to be related to hormonal effects on esophageal and gastric motility. It is important for practitioners to consider hypothyroidism as a possible cause of dysphagia after ruling out other obstructive pathologies.

CUREUS JOURNAL OF MEDICAL SCIENCE (2023)

Letter Medicine, General & Internal

Institution of an interdisciplinary IBD centre is associated with improved healthcare utilisation

Edoardo G. Giannini, Tommaso Testa, Federica Grillo, Luca Mastracci, Serena Arrigo, Piero Cai, Sabrina Paolino, Martina Burlando, Livia Pisciotta, Elena Formisano, Giuseppe Cittadini, Francesco Copello, Sabrina Tuo, Giorgia Bodini

Summary: The establishment of an interdisciplinary IBD center is associated with improved healthcare utilization, including a decrease in hospitalizations per patient/year, a decrease in length of hospitalization, and an increase in patients on biologics.

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2023)

Article Gastroenterology & Hepatology

Response to COVID-19 Vaccination in Patients with Inflammatory Bowel Disease on Biological Treatment

Giorgia Bodini, Elisabetta Giuliana, Irene Giberti, Giulia Guarona, Federica Benvenuto, Elisa Ferretti, Maria Giulia Demarzo, Giorgio Da Rin, Giancarlo Icardi, Edoardo G. Giannini

Summary: The antibody response to COVID-19 vaccination in patients with inflammatory bowel disease (IBD) on biological drugs is optimal, regardless of the mechanism of action. Patients treated with anti-TNF seem to have an earlier response to vaccination, while concomitant low-dose corticosteroids and disease activity do not appear to affect the response.

GASTROINTESTINAL DISORDERS (2022)

No Data Available