Review
Food Science & Technology
Ilaria Maria Saracino, Enzo Spisni, Veronica Imbesi, Chiara Ricci, Nikolas Konstantine Dussias, Patrizia Alvisi, Paolo Gionchetti, Fernando Rizzello, Maria Chiara Valerii
Summary: Inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis, are chronic inflammatory disorders of the digestive tract that are influenced by environmental factors including nutrition. This article reviews the bidirectional link between nutritional factors and IBD, the dietary deficits observed in IBD patients, and the potential nutritional interventions.
Review
Nutrition & Dietetics
John K. DiBaise, James S. Scolapio
Summary: This article highlights the importance of home parenteral and enteral nutrition in clinical nutrition and the development of these therapies to support patients. It emphasizes the need for healthcare providers to understand all aspects of HPEN in order to provide safe, effective, and cost-effective support to patients.
Article
Medicine, General & Internal
Roma Herman, Paulina Dumnicka, Stanislaw Pieczarkowski, Krzysztof Fyderek
Summary: Mucosal healing is the main treatment goal of Crohn's disease, and the Mucosal Inflammation Noninvasive Index (MINI) shows promise in distinguishing mucosal healing from inflammation. This study evaluated MINI in monitoring remissions induced by exclusive enteral nutrition in pediatric CD patients, and found that MINI is superior to fecal calprotectin in predicting disease relapse.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Biochemistry & Molecular Biology
HyunTaek Jung, Jae Seok Kim, Keum Hwa Lee, Kalthoum Tizaoui, Salvatore Terrazzino, Sarah Cargnin, Lee Smith, Ai Koyanagi, Louis Jacob, Han Li, Sung Hwi Hong, Dong Keon Yon, Seung Won Lee, Min Seo Kim, Paul Wasuwanich, Wikrom Karnsakul, Jae Il Shin, Andreas Kronbichler
Summary: Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract that mainly affects young people. Recent studies have shown that microRNAs (miRNAs) play an important role in the pathogenesis, diagnosis, and treatment of IBD.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
(2021)
Article
Gastroenterology & Hepatology
R. Dawson, D. I. F. Wands, M. Logan, G. Bremner, S. Efklides, L. Benn, P. Henderson, H. Grant, J. Meredith, K. Armstrong, D. C. Wilson, K. Gerasimidis, G. Alex, R. K. Russell
Summary: This study compared the outcomes of two formulas and found that a generic oral nutritional supplement and a specialized formula have similar effectiveness in inducing remission in pediatric Crohn's disease. However, using a generic oral nutritional supplement can result in significant cost savings.
INFLAMMATORY BOWEL DISEASES
(2022)
Article
Gastroenterology & Hepatology
David I. F. Wands, Laura Gianolio, David C. Wilson, Richard Hansen, Iain Chalmers, Paul Henderson, Konstantinos Gerasimidis, Richard K. Russell
Summary: In pediatric patients with CD in Scotland, the usage rates of EEN have not changed over the past 7.5 years, except during the COVID-19 pandemic, despite an increase in biologic use. Combination induction has emerged as a new trend.
INFLAMMATORY BOWEL DISEASES
(2023)
Article
Nutrition & Dietetics
Erin E. Morris, Neely C. Miller, Nicholas A. Marka, Jennifer L. Super, Emily M. Nagel, Juan David Gonzalez, Ellen W. Demerath, Sara E. Ramel
Summary: Retrospective studies show that parenteral nutrition during the first week after birth, providing calories, proteins, and lipids, is associated with improved neurodevelopment. However, an enhanced parenteral nutrition protocol in the early stage did not lead to improved neurodevelopmental outcomes. Instead, higher enteral caloric and protein intake in the first week after birth were associated with improved processing speed.
Article
Gastroenterology & Hepatology
Hamed Khalili, Niclas Hakansson, Kevin Casey, Emily Lopes, Jonas F. Ludvigsson, Andrew T. Chan, Simon S. M. Chan, Ola Olen, Alicja Wolk
Summary: This study found that certain healthy eating patterns were associated with a lower risk of older-onset Crohn's disease, but not with the risk of ulcerative colitis.
JOURNAL OF CROHNS & COLITIS
(2023)
Review
Nutrition & Dietetics
Katarzyna Ferenc, Sara Jarmakiewicz-Czaja, Rafal Filip
Summary: Inflammatory bowel disease (IBD) is a chronic disease that involves periods of exacerbation and remission. Among various factors, a low-fiber diet may contribute to the development of IBD. Dietary fiber plays an essential role in influencing the composition of the intestinal microbiota, which is associated with intestinal dysbiosis and chronic inflammation in IBD. Different components of dietary fiber, such as beta-glucan, pectin, starch, inulin, fructooligosaccharides, and hemicellulose, can significantly impact IBD prevention by modifying the composition of the intestinal microbiota or enhancing intestinal barrier function. This review aims to provide insights into the effects of individual fiber components in the diet on the risk of IBD, including alterations in the intestinal microbiota.
Review
Immunology
Susanna Esposito, Giulia Antoniol, Marialuisa Labate, Lucrezia Passadore, Patrizia Alvisi, Valeria Dacco, Chiara Ghizzi, Carla Colombo, Nicola Principi
Summary: The incidence of inflammatory bowel diseases (IBDs) is rising globally, leading to a higher risk of infections in children with dysfunctional immune systems. Vaccines are essential for preventing these infections, and should be administered according to specific immunization guidelines for IBD patients. Compliance with vaccination recommendations is generally low, highlighting the need for multidisciplinary educational programs to improve vaccination coverage and protect children with IBD from vaccine-preventable diseases.
Article
Nutrition & Dietetics
Juan Carlos Lopez-Delgado, Teodoro Grau-Carmona, Esther Mor-Marco, Maria Luisa Bordeje-Laguna, Esther Portugal-Rodriguez, Carol Lorencio-Cardenas, Paula Vera-Artazcoz, Laura Macaya-Redin, Beatriz Llorente-Ruiz, Rayden Iglesias-Rodriguez, Diana Monge-Donaire, Juan Francisco Martinez-Carmona, Laura Sanchez-Ales, Angel Sanchez-Miralles, Monica Crespo-Gomez, Cristina Leon-Cinto, Jose Luis Flordelis-Lasierra, Lluis Servia-Goixart
Summary: This study evaluated the use, complications, and nutrition delivery associated with parenteral nutrition (PN) in adult critically ill patients, especially when used early and as the initial route. The results showed that early PN administration was safe and provided adequate nutrition delivery. Additional enteral nutrition (EN), when possible, may optimize protein requirements for patients who received initial PN.
Review
Nutrition & Dietetics
Srishti Saha, Neha Patel
Summary: Inflammatory bowel disease (IBD) is a chronic disorder caused by enteric inflammation in a genetically susceptible host. Diet is widely accepted as an important factor in the pathogenesis of IBD, and various dietary components have been studied for their roles in causing enteric inflammation. Different diets, such as exclusive enteral nutrition, specific carbohydrate diet, and low FODMAPs diet, have also been explored for their effects on IBD patients. This review summarizes the current evidence on the relationship between dietary components and IBD, and provides guidance for dietary modifications in managing IBD.
Article
Nutrition & Dietetics
Darja Urlep, Rok Orel, Patricija Kunstek, Evgen Benedik
Summary: This study evaluated the clinical and endoscopic rates of remission in children with active Crohn's disease (CD) treated with partial enteral nutrition (PEN) combined with a modified Crohn's disease exclusion diet (mCDED). The study found that PEN + mCDED could potentially induce clinical and endoscopic remission in pediatric CD patients. The results provide evidence for the use of PEN + mCDED in the treatment of pediatric CD.
Review
Biochemistry & Molecular Biology
Tyler Atagozli, David E. Elliott, Mirac Nedim Ince
Summary: Helminths are multicellular invertebrates that live in the gut of vertebrate animals, including humans. They can cause pathology and require treatment, but can also have commensal or symbiotic relationships with their hosts. Epidemiological data suggests that helminth exposure may provide protection against immune disorders, such as allergies and autoimmune illnesses.
Review
Nutrition & Dietetics
Yan Jiang, Karolin Jarr, Cosima Layton, Christopher D. Gardner, Judith E. Ashouri, Maria T. Abreu, Sidhartha R. Sinha
Summary: Despite being an important issue for patients, the impact of diet on adult inflammatory bowel disease (IBD) is not well explored, with limited guidance. Current evidence on various diets used in the treatment of IBD is summarized, with potential applications of dietary data from related immune-mediated inflammatory diseases (IMIDs) to inform providers. Multiple diets, including Mediterranean, vegetarian/vegan, and reduced-calorie/fasting diets, have shown positive results in other inflammatory diseases, suggesting potential applicability to IBD, but further well-designed clinical trials are needed for guidance.
