Journal
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
Volume 29, Issue 2, Pages 123-131Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/15257771003597766
Keywords
Error-correction coding; convolutional code; similarities; dissimilarities analysis
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Funding
- Colleges and Universities' Research Foundation for Ph.D. Program of China [20050611022]
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Based on the convolutional code model of error-correction coding theory, we propose an approach to characterize and compare DNA sequences with consideration of the effect of codon context. We construct an 8-component vector whose components are the normalized leading eigenvalues of the L/L and M/M matrices associated with the original DNA sequences and the transformed sequences. The utility of our approach is illustrated by the examination of the similarities/dissimilarities among the coding sequences of the first exon of -globin gene of 11 species, and the efficiency of error-correction coding theory in analysis of similarity/dissimilarity of DNA sequences is represented.
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