Efficient, Scalable Syntheses of Linker Molecules for Metal-Organic Frameworks

Efficient synthesis protocols for five linkers of immediate interest for use in metal-organic frameworks (MOFs) are presented. The importance of scalable, cost-effective, high-yield processes with simple purifications and few steps is emphasized. The protocols allow for the efficient synthesis of biphenyl-, terphenyl-, and quaterphenyl-based linkers. Four of the linkers have been structurally characterized.