Interactions between the non-seed region of siRNA and RNA-binding RLC/RISC proteins, Ago and TRBP, in mammalian cells

Substrate-specific structural rearrangements of human Dicer

(2013) David W Taylor et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dicer-independent processing of short hairpin RNAs

(2013) Y. P. Liu et al.   NUCLEIC ACIDS RESEARCH

Distinguishable In Vitro Binding Mode of Monomeric TRBP and Dimeric PACT with siRNA

(2013) Tomoko Takahashi et al.   PLoS One

Multiple sensors ensure guide strand selection in human RNAi pathways

(2013) C. L. Noland et al.   RNA

Precursor MicroRNA-Programmed Silencing Complex Assembly Pathways in Mammals

(2012) Xuhang Liu et al.   MOLECULAR CELL

The N domain of Argonaute drives duplex unwinding during RISC assembly

(2012) Pieter Bas Kwak et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

siRNA Repositioning for Guide Strand Selection by Human Dicer Complexes

(2011) Cameron L. Noland et al.   MOLECULAR CELL

Structure of C3PO and mechanism of human RISC activation

(2011) Xuecheng Ye et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Interactions between the double-stranded RNA-binding proteins TRBP and PACT define the Medipal domain that mediates protein-protein interactions

(2011) Ghislaine Laraki et al.   RNA Biology

Dicer is dispensable for asymmetric RISC loading in mammals

(2011) J. G. Betancur et al.   RNA

Substrate-Specific Kinetics of Dicer-Catalyzed RNA Processing

(2010) Srinivas Chakravarthy et al.   JOURNAL OF MOLECULAR BIOLOGY

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis

(2010) Sihem Cheloufi et al.   NATURE

Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis

(2010) J.-S. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of the first and second double-stranded RNA-binding domains of human TAR RNA-binding protein

(2010) Seisuke Yamashita et al.   PROTEIN SCIENCE

A Novel miRNA Processing Pathway Independent of Dicer Requires Argonaute2 Catalytic Activity

(2010) D. Cifuentes et al.   SCIENCE

Structure of Arabidopsis HYPONASTIC LEAVES1 and Its Molecular Implications for miRNA Processing

(2010) Seong Wook Yang et al.   STRUCTURE

siDirect 2.0: updated software for designing functional siRNA with reduced seed-dependent off-target effect

(2009) Yuki Naito et al.   BMC BIOINFORMATICS

Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect

(2008) Kumiko Ui-Tei et al.   NUCLEIC ACIDS RESEARCH