The   isoform of topoisomerase II is required for hypercompaction of mitotic chromosomes in human cells

BAF complexes facilitate decatenation of DNA by topoisomerase IIα

(2013) Emily C. Dykhuizen et al.   NATURE

Lasonolide A, a potent and reversible inducer of chromosome condensation

(2012) Yong-Wei Zhang et al.   CELL CYCLE

Mitotic chromosome condensation in vertebrates

(2012) Paola Vagnarelli   EXPERIMENTAL CELL RESEARCH

Mitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIα

(2012) Kumiko Samejima et al.   JOURNAL OF CELL BIOLOGY

Contrasting roles of condensin I and condensin II in mitotic chromosome formation

(2012) L. C. Green et al.   JOURNAL OF CELL SCIENCE

The Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA Cleavage

(2012) Timothy J. Wendorff et al.   JOURNAL OF MOLECULAR BIOLOGY

Effects of conditional depletion of topoisomerase II on cell cycle progression in mammalian cells

(2011) Ruth E. Gonzalez et al.   CELL CYCLE

How to be a mitotic chromosome

(2011) Sandra C. Moser et al.   CHROMOSOME RESEARCH

PIASy-dependent SUMOylation regulates DNA topoisomerase IIα activity

(2010) Hyunju Ryu et al.   JOURNAL OF CELL BIOLOGY

Mitotic chromosomes are constrained by topoisomerase II–sensitive DNA entanglements

(2010) Ryo Kawamura et al.   JOURNAL OF CELL BIOLOGY

Replication Termination at Eukaryotic Chromosomes Is Mediated by Top2 and Occurs at Genomic Loci Containing Pausing Elements

(2010) Daniele Fachinetti et al.   MOLECULAR CELL

An auxin-based degron system for the rapid depletion of proteins in nonplant cells

(2009) Kohei Nishimura et al.   NATURE METHODS

Studying vertebrate topoisomerase 2 function using a conditional knockdown system in DT40 cells

(2009) M. Johnson et al.   NUCLEIC ACIDS RESEARCH

A topoisomerase II-dependent mechanism for resetting replicons at the S-M-phase transition

(2008) O. Cuvier et al.   GENES & DEVELOPMENT

Plk1-dependent Phosphorylation Regulates Functions of DNA Topoisomerase IIα in Cell Cycle Progression

(2008) Hongchang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Topoisomerase II Inactivation Prevents the Completion of DNA Replication in Budding Yeast

(2008) Jonathan Baxter et al.   MOLECULAR CELL

The SET and transposase domain protein Metnase enhances chromosome decatenation: regulation by automethylation

(2008) E. A. Williamson et al.   NUCLEIC ACIDS RESEARCH