Cell cycle stage-specific roles of Rad18 in tolerance and repair of oxidative DNA damage

c-Jun N-terminal kinase–mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forks

(2012) Laura R. Barkley et al.   MOLECULAR BIOLOGY OF THE CELL

Replication licensing promotes cyclin D1 expression and G1progression in untransformed human cells

(2011) Peijun Liu et al.   CELL CYCLE

TopBP1 and DNA polymerase alpha-mediated recruitment of the 9-1-1 complex to stalled replication forks: Implications for a replication restart-based mechanism for ATR checkpoint activation

(2011) Shan Yan et al.   CELL CYCLE

ATM activation in the presence of oxidative stress 

(2011) Zhi Guo et al.   CELL CYCLE

Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition

(2011) Komaraiah Palle et al.   CELL CYCLE

The hMsh2-hMsh6 Complex Acts in Concert with Monoubiquitinated PCNA and Pol η in Response to Oxidative DNA Damage in Human Cells

(2011) Anastasia Zlatanou et al.   MOLECULAR CELL

NBS1 Recruits RAD18 via a RAD6-like Domain and Regulates Pol η-Dependent Translesion DNA Synthesis

(2011) Hiromi Yanagihara et al.   MOLECULAR CELL

DNA damage bypass operates in the S and G2 phases of the cell cycle and exhibits differential mutagenicity

(2011) Noam Diamant et al.   NUCLEIC ACIDS RESEARCH

The RAD6 DNA Damage Tolerance Pathway Operates Uncoupled from the Replication Fork and Is Functional Beyond S Phase

(2010) Georgios I. Karras et al.   CELL

DNA damage induced Pol η recruitment takes place independently of the cell cycle phase

(2010) Gaston Soria et al.   CELL CYCLE

Phosphorylated Rad18 directs DNA Polymerase η to sites of stalled replication

(2010) Tovah A. Day et al.   JOURNAL OF CELL BIOLOGY

Three DNA Polymerases, Recruited by Different Mechanisms, Carry Out NER Repair Synthesis in Human Cells

(2010) Tomoo Ogi et al.   MOLECULAR CELL

Ubiquitin-dependent DNA damage bypass is separable from genome replication

(2010) Yasukazu Daigaku et al.   NATURE

Postreplication gaps at UV lesions are signals for checkpoint activation

(2010) A. J. Callegari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

(2010) A. Alexander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATM Activation by Oxidative Stress

(2010) Z. Guo et al.   SCIENCE

Ku Regulates the Non-Homologous End Joining Pathway Choice of DNA Double-Strand Break Repair in Human Somatic Cells

(2010) Farjana Fattah et al.   PLoS Genetics

RAD18 transmits DNA damage signalling to elicit homologous recombination repair

(2009) Jun Huang et al.   NATURE CELL BIOLOGY

The efficiency and fidelity of 8-oxo-guanine bypass by DNA polymerases   and  

(2009) S. D. McCulloch et al.   NUCLEIC ACIDS RESEARCH

Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks

(2008) Yuri Tsuji et al.   GENES TO CELLS

Rad18 is required for long-term maintenance of spermatogenesis in mouse testes

(2008) Jinghua Sun et al.   MECHANISMS OF DEVELOPMENT

Activation of Ubiquitin-Dependent DNA Damage Bypass Is Mediated by Replication Protein A

(2008) Adelina A. Davies et al.   MOLECULAR CELL

PCNA Ubiquitination and REV1 Define Temporally Distinct Mechanisms for Controlling Translesion Synthesis in the Avian Cell Line DT40

(2008) Charlotte E. Edmunds et al.   MOLECULAR CELL