Early steps of active DNA demethylation initiated by ROS1 glycosylase require three putative helix-invading residues

Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutM

(2013) Rou-Jia Sung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The DNA Repair Protein XRCC1 Functions in the Plant DNA Demethylation Pathway by Stimulating Cytosine Methylation (5-meC) Excision, Gap Tailoring, and DNA Ligation

(2013) María Isabel Martínez-Macías et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recent advances in the structural mechanisms of DNA glycosylases

(2012) Sonja C. Brooks et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Reprogramming of DNA Methylation in Pollen Guides Epigenetic Inheritance via Small RNA

(2012) Joseph P. Calarco et al.   CELL

A DNA 3′ Phosphatase Functions in Active DNA Demethylation in Arabidopsis

(2012) María Isabel Martínez-Macías et al.   MOLECULAR CELL

Demethylation initiated by ROS1 glycosylase involves random sliding along DNA

(2012) María Isabel Ponferrada-Marín et al.   NUCLEIC ACIDS RESEARCH

The recognition domain of the methyl-specific endonuclease McrBC flips out 5-methylcytosine

(2012) Rasa Sukackaite et al.   NUCLEIC ACIDS RESEARCH

Strandwise translocation of a DNA glycosylase on undamaged DNA

(2012) Y. Qi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Active DNA Demethylation in Plant Companion Cells Reinforces Transposon Methylation in Gametes

(2012) C. A. Ibarra et al.   SCIENCE

DNA Demethylation Dynamics

(2011) Nidhi Bhutani et al.   CELL

Active DNA demethylation by oxidation and repair

(2011) Zhizhong Gong et al.   CELL RESEARCH

A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo

(2011) E. Rajakumara et al.   GENES & DEVELOPMENT

Single Qdot-labeled glycosylase molecules use a wedge amino acid to probe for lesions while scanning along DNA

(2011) Andrew R. Dunn et al.   NUCLEIC ACIDS RESEARCH

Separation-of-Function Mutants Unravel the Dual-Reaction Mode of Human 8-Oxoguanine DNA Glycosylase

(2011) Bjørn Dalhus et al.   STRUCTURE

Methylation-independent DNA Binding Modulates Specificity of Repressor of Silencing 1 (ROS1) and Facilitates Demethylation in Long Substrates

(2010) María Isabel Ponferrada-Marín et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Active DNA demethylation: many roads lead to Rome

(2010) Susan C. Wu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A discontinuous DNA glycosylase domain in a family of enzymes that excise 5-methylcytosine

(2010) María Isabel Ponferrada-Marín et al.   NUCLEIC ACIDS RESEARCH

Active DNA Demethylation Mediated by DNA Glycosylases

(2009) Jian-Kang Zhu   Annual Review of Genetics

Role of Two Strictly Conserved Residues in Nucleotide Flipping andN-Glycosylic Bond Cleavage by Human Thymine DNA Glycosylase

(2009) Atanu Maiti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Entrapment and Structure of an Extrahelical Guanine Attempting to Enter the Active Site of a Bacterial DNA Glycosylase, MutM

(2009) Yan Qi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme

(2009) Yan Qi et al.   NATURE

ROS1 5-methylcytosine DNA glycosylase is a slow-turnover catalyst that initiates DNA demethylation in a distributive fashion

(2009) María Isabel Ponferrada-Marín et al.   NUCLEIC ACIDS RESEARCH

The evolving functions of DNA methylation

(2008) Daniel Zilberman   CURRENT OPINION IN PLANT BIOLOGY

The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix

(2008) Hideharu Hashimoto et al.   NATURE

Arabidopsis DEMETER-LIKE proteins DML2 and DML3 are required for appropriate distribution of DNA methylation marks

(2008) Ana Pilar Ortega-Galisteo et al.   PLANT MOLECULAR BIOLOGY