Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors  - and  -mediated transactivation

Epistatic Rescue of Nkx2.5 Adult Cardiac Conduction Disease Phenotypes by Prospero-Related Homeobox Protein 1 and HDAC3

(2012) Catherine A. Risebro et al.   CIRCULATION RESEARCH

Contribution of Common Genetic Variation to the Risk of Type 2 Diabetes in the Mexican Mestizo Population

(2012) M. A. Gamboa-Melendez et al.   DIABETES

Genetic and Molecular Insights Into the Role of PROX1 in Glucose Metabolism

(2012) S. Lecompte et al.   DIABETES

Small molecule inhibitors of RORγt: Targeting Th17 cells and other applications

(2012) Jun R. Huh et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Differential and day-time dependent expression of nuclear receptors RORα, RORβ, RORγ and RXRα in the rodent pancreas and islet

(2012) Eckhard Mühlbauer et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

(2012) Laura A. Solt et al.   NATURE

RORγ directly regulates the circadian expression of clock genes and downstream targets in vivo

(2012) Yukimasa Takeda et al.   NUCLEIC ACIDS RESEARCH

Th17-Related Genes and Celiac Disease Susceptibility

(2012) Luz María Medrano et al.   PLoS One

Genome-Wide Association Studies of Asthma in Population-Based Cohorts Confirm Known and Suggested Loci and Identify an Additional Association near HLA

(2012) Adaikalavan Ramasamy et al.   PLoS One

Crosstalk between Components of Circadian and Metabolic Cycles in Mammals

(2011) Gad Asher et al.   Cell Metabolism

Adipogenesis and insulin sensitivity in obesity are regulated by retinoid-related orphan receptor gamma

(2011) Bettina Meissburger et al.   EMBO Molecular Medicine

The REV-ERBs and RORs: molecular links between circadian rhythms and lipid homeostasis

(2011) Laura A Solt et al.   Future Medicinal Chemistry

PROX1 suppresses vitamin K-induced transcriptional activity of steroid and xenobiotic receptor

(2011) Kotaro Azuma et al.   GENES TO CELLS

Ursolic Acid Suppresses Interleukin-17 (IL-17) Production by Selectively Antagonizing the Function of RORγt Protein

(2011) Tao Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ets family members induce lymphangiogenesis through physical and functional interaction with Prox1

(2011) Y. Yoshimatsu et al.   JOURNAL OF CELL SCIENCE

Retinoid-related orphan receptor alpha and the regulation of lipid homeostasis

(2011) Rebecca L. Fitzsimmons et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

A helping hand against autoimmunity

(2011) Anton M. Jetten   NATURE

Retinoic acid-related orphan receptor γ directly regulates neuronal PAS domain protein 2 transcription in vivo

(2011) Yukimasa Takeda et al.   NUCLEIC ACIDS RESEARCH

The Retinoic Acid Receptor-Related Orphan Nuclear Receptor γ1 (RORγ1): A Novel Player Determinant of Insulin Sensitivity in Morbid Obesity

(2011) Francisco J. Tinahones et al.   Obesity

Transcriptional profiling reveals a role for RORα in regulating gene expression in obesity-associated inflammation and hepatic steatosis

(2011) Hong Soon Kang et al.   PHYSIOLOGICAL GENOMICS

The Transcriptional Control of Lymphatic Vascular Development

(2011) Mathias Francois et al.   PHYSIOLOGY

Association of New Loci Identified in European Genome-Wide Association Studies with Susceptibility to Type 2 Diabetes in the Japanese

(2011) Toshihiko Ohshige et al.   PLoS One

Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis

(2011) O. Karalay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic Convergence among ERRα, PROX1, and BMAL1 in the Control of Metabolic Clock Outputs

(2011) Catherine R. Dufour et al.   PLoS Genetics

Nuclear Receptors Linking Circadian Rhythms and Cardiometabolic Control

(2010) Hélène Duez et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Regulation of the lymphatic endothelial cell cycle by the PROX1 homeodomain protein

(2010) Shannon A. Baxter et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The homeobox protein Prox1 is a negative modulator of ERR /PGC-1  bioenergetic functions

(2010) A. Charest-Marcotte et al.   GENES & DEVELOPMENT

Characterization of the Core Mammalian Clock Component, NPAS2, as a REV-ERBα/RORα Target Gene

(2010) Christine Crumbley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

Circadian Integration of Metabolism and Energetics

(2010) J. Bass et al.   SCIENCE

Sumoylation of Prox1 controls its ability to induce VEGFR3 expression and lymphatic phenotypes in endothelial cells

(2009) M.-R. Pan et al.   JOURNAL OF CELL SCIENCE

The Benzenesulfoamide T0901317 [N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] Is a Novel Retinoic Acid Receptor-Related Orphan Receptor- /  Inverse Agonist

(2009) N. Kumar et al.   MOLECULAR PHARMACOLOGY

Convergent functional genomics of genome-wide association data for bipolar disorder: Comprehensive identification of candidate genes, pathways and mechanisms

(2008) H. Le-Niculescu et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Transcription Factor PROX1 Induces Colon Cancer Progression by Promoting the Transition from Benign to Highly Dysplastic Phenotype

(2008) Tatiana V. Petrova et al.   CANCER CELL

The Orphan Nuclear Receptor, RORα, Regulates Gene Expression That Controls Lipid Metabolism

(2008) Patrick Lau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY