Functional screening for miRNAs targeting Smad4 identified miR-199a as a negative regulator of TGF-β signalling pathway

Altered microRNA Expression Patterns in Hepatoblastoma Patients

(2014) Armando Magrelli et al.   Translational Oncology

MiRNA-335 suppresses neuroblastoma cell invasiveness by direct targeting of multiple genes from the non-canonical TGF-β signalling pathway

(2012) Jennifer Lynch et al.   CARCINOGENESIS

Smad4-mediated TGF-β signaling in tumorigenesis

(2012) Guan Yang et al.   International Journal of Biological Sciences

MicroRNA-130a-mediated down-regulation of Smad4 contributes to reduced sensitivity to TGF- 1 stimulation in granulocytic precursors

(2011) M. Hager et al.   BLOOD

Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice

(2011) Jian Wang et al.   CELL RESEARCH

MiR-199a attenuates endometrial stromal cell invasiveness through suppression of the IKK /NF- B pathway and reduced interleukin-8 expression

(2011) L. Dai et al.   MOLECULAR HUMAN REPRODUCTION

SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression

(2011) Zhihu Ding et al.   NATURE

Methylation of an intronic region regulates miR-199a in testicular tumor malignancy

(2011) H-H Cheung et al.   ONCOGENE

MicroRNA miR-146b-5p regulates signal transduction of TGF-β by repressing SMAD4 in thyroid cancer

(2011) M V Geraldo et al.   ONCOGENE

Cytoscape 2.8: new features for data integration and network visualization

(2010) M. E. Smoot et al.   BIOINFORMATICS

miR-199a Regulates the Tumor Suppressor Mitogen-Activated Protein Kinase Kinase Kinase 11 in Gastric Cancer

(2010) Guang Song et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Targeting Smad4 links microRNA-146a to the TGF-β pathway during retinoid acid induction in acute promyelocytic leukemia cell line

(2010) Hua Zhong et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

MicroRNA-26a is a novel regulator of vascular smooth muscle cell function

(2010) Nicholas J. Leeper et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion

(2010) Qingli Shen et al.   Molecular Cancer

The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-β Pathway in Neuroblastoma

(2010) Pieter Mestdagh et al.   MOLECULAR CELL

MicroRNA-224 Is Involved in Transforming Growth Factor-β-Mediated Mouse Granulosa Cell Proliferation and Granulosa Cell Function by Targeting Smad4

(2010) Guidong Yao et al.   MOLECULAR ENDOCRINOLOGY

Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3′ untranslated region

(2010) S Wu et al.   ONCOGENE

DIANA-mirPath: Integrating human and mouse microRNAs in pathways

(2009) G. L. Papadopoulos et al.   BIOINFORMATICS

Breast Cancer Metastasis Suppressor 1 Up-regulates miR-146, Which Suppresses Breast Cancer Metastasis

(2009) Douglas R. Hurst et al.   CANCER RESEARCH

FAM/USP9x, a Deubiquitinating Enzyme Essential for TGFβ Signaling, Controls Smad4 Monoubiquitination

(2009) Sirio Dupont et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

miR-210 promotes osteoblastic differentiation through inhibition ofAcvR1b

(2009) Yosuke Mizuno et al.   FEBS LETTERS

MicroRNA-23b cluster microRNAs regulate transforming growth factor-beta/bone morphogenetic protein signaling and liver stem cell differentiation by targeting Smads

(2009) Charles E. Rogler et al.   HEPATOLOGY

miR-199a*, a Bone Morphogenic Protein 2-responsive MicroRNA, Regulates Chondrogenesis via Direct Targeting to Smad1

(2009) Edward A. Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis

(2009) Tetsuya Ueda et al.   LANCET ONCOLOGY

Disruption of Smad4 in Odontoblasts Causes Multiple Keratocystic Odontogenic Tumors and Tooth Malformation in Mice

(2009) Y. Gao et al.   MOLECULAR AND CELLULAR BIOLOGY

TGF-β activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN

(2009) Mitsuo Kato et al.   NATURE CELL BIOLOGY

Synergistic action of Smad4 and Pten in suppressing pancreatic ductal adenocarcinoma formation in mice

(2009) X Xu et al.   ONCOGENE

MicroRNA-21 Targets a Network of Key Tumor-Suppressive Pathways in Glioblastoma Cells

(2008) T. Papagiannakopoulos et al.   CANCER RESEARCH

A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis

(2008) Jie Shen et al.   CARCINOGENESIS

TGFβ in Cancer

(2008) Joan Massagué   CELL

Altered MicroRNA Expression in Cervical Carcinomas

(2008) J.-W. Lee et al.   CLINICAL CANCER RESEARCH

MicroRNA-155 Is Regulated by the Transforming Growth Factor  /Smad Pathway and Contributes to Epithelial Cell Plasticity by Targeting RhoA

(2008) W. Kong et al.   MOLECULAR AND CELLULAR BIOLOGY

SMAD proteins control DROSHA-mediated microRNA maturation

(2008) Brandi N. Davis et al.   NATURE

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis

(2008) Qihong Huang et al.   NATURE CELL BIOLOGY

Transforming growth factor- -regulated miR-24 promotes skeletal muscle differentiation

(2008) Q. Sun et al.   NUCLEIC ACIDS RESEARCH

Regulation of IKKβ by miR-199a affects NF-κB activity in ovarian cancer cells

(2008) R Chen et al.   ONCOGENE

Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system

(2008) B. Schmierer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct microRNA expression profiles in acute myeloid leukemia with common translocations

(2008) Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin

(2008) R. Garzon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA miR-24 inhibits erythropoiesis by targeting activin type I receptor ALK4

(2007) Q. Wang et al.   BLOOD