TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1

Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Repairs DNA Damage Induced by Topoisomerases I and II and Base Alkylation in Vertebrate Cells

(2012) Junko Murai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair

(2012) Jessica J.R. Hudson et al.   Nature Communications

Effects of DNA and protein size on substrate cleavage by human tyrosyl-DNA phosphodiesterase 1

(2011) Heidrun Interthal et al.   BIOCHEMICAL JOURNAL

The PML nuclear bodies-associated protein TTRAP regulates ribosome biogenesis in nucleolar cavities upon proteasome inhibition

(2011) S Vilotti et al.   CELL DEATH AND DIFFERENTIATION

To live or to die: a matter of processing damaged DNA termini in neurons

(2011) Sherif F. El-Khamisy   EMBO Molecular Medicine

TTRAP Is a Novel Component of the Non-Canonical TRAF6-TAK1 TGF-β Signaling Pathway

(2011) György Várady et al.   PLoS One

DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs

(2010) Yves Pommier et al.   CHEMISTRY & BIOLOGY

TDP2/TTRAP Is the Major 5′-Tyrosyl DNA Phosphodiesterase Activity in Vertebrate Cells and Is Critical for Cellular Resistance to Topoisomerase II-induced DNA Damage

(2010) Zhihong Zeng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin

(2009) Sherif F. El-Khamisy et al.   DNA REPAIR

Tyrosyl-DNA phosphodiesterase and the repair of 3′-phosphoglycolate-terminated DNA double-strand breaks

(2009) Tong Zhou et al.   DNA REPAIR

A human 5′-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage

(2009) Felipe Cortes Ledesma et al.   NATURE