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Comprehensive computational design of mCreI homing endonuclease cleavage specificity for genome engineering

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

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Mechanism of DNA Recognition by the Restriction Enzyme EcoRV

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Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus

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MolProbity: all-atom structure validation for macromolecular crystallography

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Homing endonucleases: from basics to therapeutic applications

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Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease

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Recent advances in the study of nucleic acid flexibility by molecular dynamics

(2008) Modesto Orozco et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Molecular dynamics simulations of nucleic acid–protein complexes

(2008) Alexander D MacKerell et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases

(2008) Pilar Redondo et al.   NATURE

Displacement of protein-bound aptamers with small molecules screened by fluorescence polarization

(2008) Markus Hafner et al.   Nature Protocols

3DNA: a versatile, integrated software system for the analysis, rebuilding and visualization of three-dimensional nucleic-acid structures

(2008) Xiang-Jun Lu et al.   Nature Protocols

Crystal structure of I-DmoI in complex with its target DNA provides new insights into meganuclease engineering

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