PocketQuery: protein-protein interaction inhibitor starting points from protein-protein interaction structure

Small-molecule inhibitor starting points learned from protein–protein interaction inhibitor structure

(2012) David Ryan Koes et al.   BIOINFORMATICS

The Structure-Based Design of Mdm2/Mdmx-p53 Inhibitors Gets Serious

(2011) Grzegorz M. Popowicz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

KFC2: A knowledge-based hot spot prediction method based on interface solvation, atomic density, and plasticity features

(2011) Xiaolei Zhu et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication

(2010) Frauke Christ et al.   Nature Chemical Biology

ANCHOR: a web server and database for analysis of protein-protein interaction binding pockets for drug discovery

(2010) L. M. C. Meireles et al.   NUCLEIC ACIDS RESEARCH

Identification of computational hot spots in protein interfaces: combining solvent accessibility and inter-residue potentials improves the accuracy

(2009) Nurcan Tuncbag et al.   BIOINFORMATICS

Prediction of hot spot residues at protein-protein interfaces by combining machine learning and energy-based methods

(2009) Stefano Lise et al.   BMC BIOINFORMATICS

A survey of available tools and web servers for analysis of protein-protein interactions and interfaces

(2009) N. Tuncbag et al.   BRIEFINGS IN BIOINFORMATICS

Rationalizing the chemical space of protein–protein interaction inhibitors

(2009) Olivier Sperandio et al.   DRUG DISCOVERY TODAY

A feature-based approach to modeling protein–protein interaction hot spots

(2009) Kyu-il Cho et al.   NUCLEIC ACIDS RESEARCH

Comprehensive in silico mutagenesis highlights functionally important residues in proteins

(2008) Y. Bromberg et al.   BIOINFORMATICS

Small molecular weight protein–protein interaction antagonists—an insurmountable challenge?

(2008) Alexander Dömling   CURRENT OPINION IN CHEMICAL BIOLOGY