NetwoRx: connecting drugs to networks and phenotypes in Saccharomyces cerevisiae

Network-based characterization of drug-regulated genes, drug targets, and toxicity

(2012) Max Kotlyar et al.   METHODS

Mitochondrial Electron Transport Is the Cellular Target of the Oncology Drug Elesclomol

(2012) Ronald K. Blackman et al.   PLoS One

Integrative computational biology for cancer research

(2011) Kristen Fortney et al.   HUMAN GENETICS

Bugs, drugs and chemical genomics

(2011) Terry Roemer et al.   Nature Chemical Biology

STITCH 3: zooming in on protein-chemical interactions

(2011) M. Kuhn et al.   NUCLEIC ACIDS RESEARCH

The Gene Ontology: enhancements for 2011

(2011)   NUCLEIC ACIDS RESEARCH

SuperTarget goes quantitative: update on drug-target interactions

(2011) N. Hecker et al.   NUCLEIC ACIDS RESEARCH

Saccharomyces Genome Database: the genomics resource of budding yeast

(2011) J. M. Cherry et al.   NUCLEIC ACIDS RESEARCH

KEGG for integration and interpretation of large-scale molecular data sets

(2011) M. Kanehisa et al.   NUCLEIC ACIDS RESEARCH

A Genome-wide Camptothecin Sensitivity Screen Identifies a Mammalian MMS22L-NFKBIL2 Complex Required for Genomic Stability

(2010) Brenda C. O'Connell et al.   MOLECULAR CELL

Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action

(2010) Laura Kapitzky et al.   Molecular Systems Biology

The Comparative Toxicogenomics Database: update 2011

(2010) A. P. Davis et al.   NUCLEIC ACIDS RESEARCH

YEASTRACT: providing a programmatic access to curated transcriptional regulatory associations in Saccharomyces cerevisiae through a web services interface

(2010) D. Abdulrehman et al.   NUCLEIC ACIDS RESEARCH

DrugBank 3.0: a comprehensive resource for 'Omics' research on drugs

(2010) C. Knox et al.   NUCLEIC ACIDS RESEARCH

A survey of yeast genomic assays for drug and target discovery

(2010) Andrew M. Smith et al.   PHARMACOLOGY & THERAPEUTICS

Discovery of drug mode of action and drug repositioning from transcriptional responses

(2010) F. Iorio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Curcumin Extends Life Span, Improves Health Span, and Modulates the Expression of Age-Associated Aging Genes in Drosophila melanogaster

(2010) Kyu-Sun Lee et al.   REJUVENATION RESEARCH

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

Genome-Wide Screen in Saccharomyces cerevisiae Identifies Vacuolar Protein Sorting, Autophagy, Biosynthetic, and tRNA Methylation Genes Involved in Life Span Regulation

(2010) Paola Fabrizio et al.   PLoS Genetics

A Microarray-Based Genetic Screen for Yeast Chronological Aging Factors

(2010) Mirela Matecic et al.   PLoS Genetics

Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action

(2010) Maureen E Hillenmeyer et al.   GENOME BIOLOGY

NAViGaTOR: Network Analysis, Visualization and Graphing Toronto

(2009) Kevin R. Brown et al.   BIOINFORMATICS

Meta-analysis of age-related gene expression profiles identifies common signatures of aging

(2009) João Pedro de Magalhães et al.   BIOINFORMATICS

Saccharomyces Genome Database provides mutant phenotype data

(2009) S. R. Engel et al.   NUCLEIC ACIDS RESEARCH

Pharmacological Inhibition of Phosphoinositide 3 and TOR Kinases Improves Survival of Drosophila melanogaster

(2009) A.A. Moskalev et al.   REJUVENATION RESEARCH

Systems medicine: the future of medical genomics and healthcare

(2009) Charles Auffray et al.   Genome Medicine

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Data completeness—the Achilles heel of drug-target networks

(2008) Jordi Mestres et al.   NATURE BIOTECHNOLOGY

The Chemical Genomic Portrait of Yeast: Uncovering a Phenotype for All Genes

(2008) M. E. Hillenmeyer et al.   SCIENCE

Cancer Proliferation Gene Discovery Through Functional Genomics

(2008) M. R. Schlabach et al.   SCIENCE

Off-Target Effects of Psychoactive Drugs Revealed by Genome-Wide Assays in Yeast

(2008) Elke Ericson et al.   PLoS Genetics