Handpicking epigenetic marks with PHD fingers

Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions

(2011) Alexander J. Ruthenburg et al.   CELL

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Plant Homeodomain (PHD) Fingers of CHD4 Are Histone H3-binding Modules with Preference for Unmodified H3K4 and Methylated H3K9

(2011) Robyn E. Mansfield et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome

(2011) Shigeki Iwase et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The PHD3 Domain of MLL Acts as a CYP33-Regulated Switch between MLL-Mediated Activation and Repression,

(2010) Sangho Park et al.   BIOCHEMISTRY

Pro Isomerization in MLL1 PHD3-Bromo Cassette Connects H3K4me Readout to CyP33 and HDAC-Mediated Repression

(2010) Zhanxin Wang et al.   CELL

Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans

(2010) Ying Yang et al.   CELL RESEARCH

Influence of Combinatorial Histone Modifications on Antibody and Effector Protein Recognition

(2010) Stephen M. Fuchs et al.   CURRENT BIOLOGY

Recognition of Histone H3K4 Trimethylation by the Plant Homeodomain of PHF2 Modulates Histone Demethylation

(2010) Hong Wen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Allosteric Remodelling of the Histone H3 Binding Pocket in the Pygo2 PHD Finger Triggered by Its Binding to the B9L/BCL9 Co-Factor

(2010) Thomas C.R. Miller et al.   JOURNAL OF MOLECULAR BIOLOGY

Binding of the MLL PHD3 Finger to Histone H3K4me3 Is Required for MLL-Dependent Gene Transcription

(2010) Pei-Yun Chang et al.   JOURNAL OF MOLECULAR BIOLOGY

Molecular Mechanism of MLL PHD3 and RNA Recognition by the Cyp33 RRM Domain

(2010) Robert A. Hom et al.   JOURNAL OF MOLECULAR BIOLOGY

PHD Fingers: Epigenetic Effectors and Potential Drug Targets

(2010) C. A. Musselman et al.   MOLECULAR INTERVENTIONS

Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development

(2010) Hank H. Qi et al.   NATURE

Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b

(2010) Lei Zeng et al.   NATURE

TRIM24 links a non-canonical histone signature to breast cancer

(2010) Wen-Wei Tsai et al.   NATURE

Combinatorial profiling of chromatin binding modules reveals multisite discrimination

(2010) Adam L Garske et al.   Nature Chemical Biology

PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation

(2010) Weijun Feng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications

(2009) Catherine A. Musselman et al.   BIOCHEMICAL JOURNAL

Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX–DNMT3–DNMT3L domain

(2009) Junji Otani et al.   EMBO REPORTS

ING4 Mediates Crosstalk between Histone H3 K4 Trimethylation and H3 Acetylation to Attenuate Cellular Transformation

(2009) Tiffany Hung et al.   MOLECULAR CELL

HBO1 HAT Complexes Target Chromatin throughout Gene Coding Regions via Multiple PHD Finger Interactions with Histone H3 Tail

(2009) Nehmé Saksouk et al.   MOLECULAR CELL

Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger

(2009) Gang G. Wang et al.   NATURE

Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases

(2009) John R Horton et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation

(2009) Francesca Chignola et al.   NUCLEIC ACIDS RESEARCH

Structure and Site-Specific Recognition of Histone H3 by the PHD Finger of Human Autoimmune Regulator

(2009) Suvobrata Chakravarty et al.   STRUCTURE

Histones: Annotating Chromatin

(2008) Eric I. Campos et al.   Annual Review of Genetics

Lid2 Is Required for Coordinating H3K4 and H3K9 Methylation of Heterochromatin and Euchromatin

(2008) Fei Li et al.   CELL

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

(2008) Tõnis Org et al.   EMBO REPORTS

Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex

(2008) M. Lange et al.   GENES & DEVELOPMENT

Molecular Basis of Histone H3K4me3 Recognition by ING4

(2008) Alicia Palacios et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone H3K4me3 Binding Is Required for the DNA Repair and Apoptotic Activities of ING1 Tumor Suppressor

(2008) P.V. Peña et al.   JOURNAL OF MOLECULAR BIOLOGY

Decoding of Methylated Histone H3 Tail by the Pygo-BCL9 Wnt Signaling Complex

(2008) Marc Fiedler et al.   MOLECULAR CELL

Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity

(2008) A. S. Koh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The crystal structure of the ING5 PHD finger in complex with an H3K4me3 histone peptide

(2008) Karen S. Champagne et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Structural Insight into the Recognition of the H3K4me3 Mark by the TFIID Subunit TAF3

(2008) Hugo van Ingen et al.   STRUCTURE