FRET analysis reveals distinct conformations of IN tetramers in the presence of viral DNA or LEDGF/p75

Dithiothreitol Causes HIV-1 Integrase Dimer Dissociation While Agents Interacting With the Integrase Dimer Interface Promote Dimer Formation

(2011) Manuel Tsiang et al.   BIOCHEMISTRY

Structural Properties of HIV Integrase·Lens Epithelium-derived Growth Factor Oligomers

(2010) Kushol Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleoprotein Intermediates in HIV-1 DNA Integration Visualized by Atomic Force Microscopy

(2010) Svetlana Kotova et al.   JOURNAL OF MOLECULAR BIOLOGY

Retroviral intasome assembly and inhibition of DNA strand transfer

(2010) Stephen Hare et al.   NATURE

Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication

(2010) Frauke Christ et al.   Nature Chemical Biology

Structure-based modeling of the functional HIV-1 intasome and its inhibition

(2010) L. Krishnan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Time-Resolved Fluorescence Resonance Energy Transfer Study Shows a Compact Denatured State of the B Domain of Protein A†

(2009) F. Huang et al.   BIOCHEMISTRY

Structural basis for HIV-1 DNA integration in the human genome, role of the LEDGF/P75 cofactor

(2009) Fabrice Michel et al.   EMBO JOURNAL

Affinities between the Binding Partners of the HIV-1 Integrase Dimer-Lens Epithelium-derived Growth Factor (IN Dimer-LEDGF) Complex

(2009) Manuel Tsiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleoprotein complex intermediates in HIV-1 integration

(2009) Min Li et al.   METHODS

An Allosteric Mechanism for Inhibiting HIV-1 Integrase with a Small Molecule

(2009) J. J. Kessl et al.   MOLECULAR PHARMACOLOGY

HIV-1 Integrase-DNA Recognition Mechanisms

(2009) Jacques Kessl et al.   Viruses-Basel

A Novel Co-Crystal Structure Affords the Design of Gain-of-Function Lentiviral Integrase Mutants in the Presence of Modified PSIP1/LEDGF/p75

(2009) Stephen Hare et al.   PLoS Pathogens

Structural Basis for Functional Tetramerization of Lentiviral Integrase

(2009) Stephen Hare et al.   PLoS Pathogens

Dynamic Modulation of HIV-1 Integrase Structure and Function by Cellular Lens Epithelium-derived Growth Factor (LEDGF) Protein

(2008) Christopher J. McKee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Lentiviral Integrase Binding Protein LEDGF/p75 and HIV-1 Replication

(2008) Alan Engelman et al.   PLoS Pathogens