Effect of base sequence on the DNA cross-linking properties of pyrrolobenzodiazepine (PBD) dimers

Pyrrolo[2,1-c][1,4]benzodiazepine as a Scaffold for the Design and Synthesis of Anti- Tumour Drugs

(2012) Laura Cipolla et al.   Anti-Cancer Agents in Medicinal Chemistry

Phase I Pharmacokinetic and Pharmacodynamic Study of SJG-136, a Novel DNA Sequence Selective Minor Groove Cross-linking Agent, in Advanced Solid Tumors

(2011) I. Puzanov et al.   CLINICAL CANCER RESEARCH

Histone  H2AX and Poly(ADP-Ribose) as Clinical Pharmacodynamic Biomarkers

(2010) C. E. Redon et al.   CLINICAL CANCER RESEARCH

DNA Sequence Preference and Adduct Orientation of Pyrrolo[2,1-c][1,4]benzodiazepine Antitumor Agents

(2010) Khondaker M. Rahman et al.   ACS Medicinal Chemistry Letters

A phase I trial of SJG-136 (NSC#694501) in advanced solid tumors

(2009) Yelena Y. Janjigian et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Phase I Study of Sequence-Selective Minor Groove DNA Binding Agent SJG-136 in Patients with Advanced Solid Tumors

(2009) D. Hochhauser et al.   CLINICAL CANCER RESEARCH

The Pyrrolobenzodiazepine Dimer SJG-136 Forms Sequence-Dependent Intrastrand DNA Cross-Links and Monoalkylated Adducts in Addition to Interstrand Cross-Links

(2009) Khondaker M. Rahman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Observation of a dynamic equilibrium between DNA hairpin and duplex forms of covalent adducts of a minor groove binding agent

(2008) Khondaker M. Rahman et al.   CHEMICAL COMMUNICATIONS

An assay combining high-performance liquid chromatography and mass spectrometry to measure DNA interstrand cross-linking efficiency in oligonucleotides of varying sequences

(2007) Mathangi Narayanaswamy et al.   ANALYTICAL BIOCHEMISTRY