UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation

Uracil-DNA Glycosylase in Base Excision Repair and Adaptive Immunity

(2011) Berit Doseth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Incorporation of 5-Fluorouracil into RNA Affects the Ribonucleolytic Activity of the Exosome Subunit Rrp6

(2011) R. A. Silverstein et al.   MOLECULAR CANCER RESEARCH

Effect of the Thymidylate Synthase Inhibitors on dUTP and TTP Pool Levels and the Activities of DNA Repair Glycosylases on Uracil and 5-Fluorouracil in DNA

(2010) Breeana C. Grogan et al.   BIOCHEMISTRY

Defective Mismatch Repair As a Predictive Marker for Lack of Efficacy of Fluorouracil-Based Adjuvant Therapy in Colon Cancer

(2010) Daniel J. Sargent et al.   JOURNAL OF CLINICAL ONCOLOGY

Impairment of APE1 Function Enhances Cellular Sensitivity to Clinically Relevant Alkylators and Antimetabolites

(2009) D. R. McNeill et al.   MOLECULAR CANCER RESEARCH

Base Excision by Thymine DNA Glycosylase Mediates DNA-Directed Cytotoxicity of 5-Fluorouracil

(2009) Christophe Kunz et al.   PLOS BIOLOGY

Participation of DNA repair in the response to 5-fluorouracil

(2008) M. D. Wyatt et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The rate of base excision repair of uracil is controlled by the initiating glycosylase

(2008) Torkild Visnes et al.   DNA REPAIR

The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine

(2008) Angen Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Evidence that tRNA modifying enzymes are important in vivo targets for 5-fluorouracil in yeast

(2008) M. Gustavsson et al.   RNA

Uracil incorporation into genomic DNA does not predict toxicity caused by chemotherapeutic inhibition of thymidylate synthase

(2007) Yuhong Luo et al.   DNA REPAIR