Thermodynamic stability and Watson–Crick base pairing in the seed duplex are major determinants of the efficiency of the siRNA-based off-target effect

Title
Thermodynamic stability and Watson–Crick base pairing in the seed duplex are major determinants of the efficiency of the siRNA-based off-target effect
Authors
Keywords
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Journal
NUCLEIC ACIDS RESEARCH
Volume 36, Issue 22, Pages 7100-7109
Publisher
Oxford University Press (OUP)
Online
2008-11-07
DOI
10.1093/nar/gkn902

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