Journal
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT
Volume 628, Issue 1, Pages 419-422Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.nima.2010.07.015
Keywords
Silicon microstrip detector; Synchrotron radiation; Mammography; Breast compuled tomography
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The SYRMEP (Synchrotron Radiation for Medical Physics) collaboration has performed, for the first time in the world, a clinical program of mammography with synchrotron radiation. This program provided excellent results, although utilizing a commercial screen-film system as a detector. The PICASSO (Phase Imaging for Clinical Application with Silicon detector and Synchrotron radiation) project has developed a detector prototype capable of fully exploiting the peculiar characteristics of the synchrotron source, utilizing silicon microstrip sensors illuminated in the edge-on geometry and operated in single-photon counting. In this paper the potential of the PICASSO detector in breast computed tomography was evaluated by means of custom phantoms. Very encouraging results have been obtained with severe dose constrains as far as both spatial and contrast resolution are concerned. Moreover, the capability of detecting phase contrast effects was demonstrated, albeit with a higher delivered dose. (C) 2010 Elsevier B.V. All rights reserved.
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