4.6 Editorial Material

The dilemma of controlling heavy metal accumulation in plants

Journal

NEW PHYTOLOGIST
Volume 181, Issue 1, Pages 3-5

Publisher

WILEY
DOI: 10.1111/j.1469-8137.2008.02699.x

Keywords

zinc; cadmium; heavy metal ATPase; CPx-ATPase; xylem loading; phytoremediation; biofortification; metal accumulation

Categories

Ask authors/readers for more resources

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.6
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Plant Sciences

Arabidopsis thaliana Zn2+-efflux ATPases HMA2 and HMA4 are required for resistance to the necrotrophic fungus Plectosphaerella cucumerina BMM

Viviana Escudero, Dario Ferreira Sanchez, Isidro Abreu, Sara Sopena-Torres, Natalia Makarovsky-Saavedra, Maria Bernal, Ute Kramer, Daniel Grolimund, Manuel Gonzalez-Guerrero, Lucia Jorda

Summary: Zinc plays a role in resistance to PcBMM infection in plants with ordinary zinc levels, and its accumulation is associated with up-regulation of HEAVY METAL ATPASE2 and HEAVY METAL ATPASE4 expression, enhancing resistance.

JOURNAL OF EXPERIMENTAL BOTANY (2022)

Review Biochemistry & Molecular Biology

Zinc in plants: Integrating homeostasis and biofortification

Camilla Stanton, Dale Sanders, Ute Kraemer, Dorina Podar

Summary: This article reviews the current understanding of zinc homeostasis in plants, focusing on the balance between zinc supply and nutritional requirements in soil, as well as the importance of zinc for plant and human health.

MOLECULAR PLANT (2022)

Article Plant Sciences

Constitutively enhanced genome integrity maintenance and direct stress mitigation characterize transcriptome of extreme stress-adapted Arabidopsis halleri

Gwonjin Lee, Hassan Ahmadi, Julia Quintana, Lara Syllwasschy, Nadezda Janina, Veronica Preite, Justin E. Anderson, Bjorn Pietzenuk, Ute Kramer

Summary: The study found that Arabidopsis halleri exhibits higher tolerance and regulation of cadmium accumulation in heavy metal-contaminated soils, with decreased transcriptomic response to cadmium. Plants from highly metalliferous soils show elevated AGO9 and HMA2 transcript levels, which may contribute to their adaptation to extreme abiotic stress.

PLANT JOURNAL (2021)

Article Plant Sciences

Root-to-shoot iron partitioning in Arabidopsis requires IRON-REGULATED TRANSPORTER1 (IRT1) protein but not its iron(II) transport function

Julia Quintana, Maria Bernal, Marleen Scholle, Heike Hollaender-Czytko, Nga T. Nguyen, Markus Piotrowski, David G. Mendoza-Cozatl, Michael J. Haydon, Ute Kraemer

Summary: The study reveals a second role of IRT1 in root-to-shoot partitioning of iron in Arabidopsis thaliana, in addition to its primary function in high-affinity iron uptake in roots. Mutations in IRT1 lead to iron overaccumulation in roots, highlighting a new aspect of IRT1's involvement in iron homeostasis. Furthermore, findings suggest a regulatory function for IRT1 in iron mobilization that is independent of its transport activity.

PLANT JOURNAL (2022)

Article Plant Sciences

Chloroplast Ribosomes Interact With the Insertase Alb3 in the Thylakoid Membrane

Bernd Ackermann, Beatrix Duenschede, Bjoern Pietzenuk, Bo Hojen Justesen, Ute Kraemer, Eckhard Hofmann, Thomas Guenther Pomorski, Danja Schuenemann

Summary: Members of the Oxa1/YidC/Alb3 protein family are involved in the insertion, folding, and assembly of membrane proteins in mitochondria, bacteria, and chloroplasts. The thylakoid membrane protein Alb3 interacts with ribosomes during posttranslational insertion of specific proteins, while Alb4, a homolog located in the same membrane, does not show ribosome binding. Alb3 contacts ribosomes via its C-terminal region and at least one additional binding site within its hydrophobic core.

FRONTIERS IN PLANT SCIENCE (2021)

Article Plant Sciences

Involvement of Arabidopsis Multi-Copper Oxidase-Encoding LACCASE12 in Root-to-Shoot Iron Partitioning: A Novel Example of Copper-Iron Crosstalk

Maria Bernal, Ute Kraemer

Summary: The text discusses the interaction between iron and copper in biological systems and their importance in biological processes. Studies have found an inter-dependence of iron and copper in certain eukaryotes, including green algae, yeast, and mammals. In Arabidopsis, copper deficiency can lead to secondary iron deficiency, affecting root-to-shoot iron translocation and ferroxidase activity.

FRONTIERS IN PLANT SCIENCE (2021)

Article Multidisciplinary Sciences

A two-step adaptive walk rewires nutrient transport in a challenging edaphic environment

Emmanuel Tergemina, Ahmed F. Elfarargi, Paulina Flis, Andrea Fulgione, Mehmet Goektay, Celia Neto, Marleen Scholle, Padraic J. Flood, Sophie-Asako Xerri, Johan Zicola, Nina Doering, Herculano Dinis, Ute Kraemer, David E. Salt, Angela M. Hancock

Summary: This study demonstrates a two-step evolutionary process in which nutrient homeostasis was rewired to adapt to extremely low soil manganese conditions. A variant disrupting the iron uptake transporter gene quickly became fixed in the population, increasing manganese but limiting iron in the leaves. Multiple independent gene duplications then compensated for the loss of the iron transporter gene, improving iron homeostasis. This research provides a clear example of a multilocus adaptive walk and sheds light on how genetic variants reshape phenotypes and spread over space and time.

SCIENCE ADVANCES (2022)

Article Biochemistry & Molecular Biology

Energy status-promoted growth and development of Arabidopsis require copper deficiency response transcriptional regulator SPL7

Anna Schulten, Bjoern Pietzenuk, Julia Quintana, Marleen Scholle, Regina Feil, Marcus Krause, Maida Romera-Branchat, Vanessa Wahl, Edouard Severing, George Coupland, Ute Kraemer

Summary: Copper is crucial for energy production and carbon fixation in Arabidopsis, and SPL7 is a transcription factor involved in the response to copper deficiency. In this study, it was found that SPL7 mutants are unable to translate sugar levels into growth and development under copper-deficient conditions, and therefore cannot be stimulated by exogenous sugar supplementation.

PLANT CELL (2022)

Article Biochemical Research Methods

Effects of 4-Br-A23187 on Bacillus subtilis cells and unilamellar vesicles reveal it to be a potent copper ionophore

Christoph H. R. Senges, Helen L. Warmuth, Melissa Vazquez-Hernandez, Huriye Deniz Uzun, Leonie Sagurna, Pascal Dietze, Claudia Schmidt, Brix Muecher, Stefan Herlitze, Ute Kraemer, Ingo Ott, Thomas Gunther Pomorski, Julia E. Bandow

Summary: Ionophores are small molecules or peptides that transport metal ions across biological membranes. In this study, the effects of the semisynthetic polyether ionophore 4-Br-A23187 on the model organism Bacillus subtilis were investigated. The treatment led to an increase in intracellular copper levels and a decrease in intracellular manganese and magnesium, which resulted in oxidative stress and disturbance of proteostasis. A liposome model confirmed the ionophore's role as a copper transporter in vitro.

PROTEOMICS (2022)

Article Multidisciplinary Sciences

Translational fidelity and growth of Arabidopsis require stress-sensitive diphthamide biosynthesis

Hongliang Zhang, Julia Quintana, Koray Uetkuer, Lorenz Adrian, Harmen Hawer, Klaus Mayer, Xiaodi Gong, Leonardo Castanedo, Anna Schulten, Nadezda Janina, Marcus Peters, Markus Wirtz, Ulrich Brinkmann, Raffael Schaffrath, Ute Kraemer

Summary: Diphthamide, a post-translational modification of eukaryotic translation elongation factor 2, is conserved in Arabidopsis thaliana and contributes to translational fidelity and growth by regulating cell proliferation. Diphthamide modification depends on specific proteins and its unmodification leads to increased ribosomal frameshifting-errors and decreased cell formation. Under abiotic stress, unmodified eEF2 accumulates in wild-type seedlings, suggesting its conservation across species.

NATURE COMMUNICATIONS (2022)

Article Environmental Sciences

Elemental bioimaging of Zn and Cd in leaves of hyperaccumulator Arabidopsis halleri using laser ablation-inductively coupled plasma-mass spectrometry and referencing strategies

Maximilian von Bremen-Kuehne, Hassan Ahmadi, Michael Sperling, Ute Kraemer, Uwe Karst

Summary: The spatial distribution of Zn and Cd in leaves of Arabidopsis halleri was determined using LA-ICP-MS. Referencing to internal standard elements was used to compensate for experimental issues. C-13 was found to be the most suitable element for referencing, stabilizing the distribution of Zn and Cd even in samples affected by experimental issues.

CHEMOSPHERE (2022)

Article Biochemistry & Molecular Biology

Effects of metal amendment and metalloid supplementation on foliar defences are plant accession-specific in the hyperaccumulator Arabidopsis halleri

Rocky Putra, Max Toelle, Ute Kraemer, Caroline Mueller

Summary: Soil pollution by metals and metalloids due to industrialization has a detrimental effect on ecosystems. Certain plant species called hyperaccumulators can accumulate high concentrations of these metals and metalloids in their aboveground tissues, acting as a defense against various antagonists. This study investigates the effects of metal(loid)s on defense traits in the hyperaccumulator plant species Arabidopsis halleri by artificially amending the soil with cadmium and zinc, and supplementing with silicon. The results show significant effects of metal amendment and silicon supplementation on foliar concentrations of certain elements, as well as on organic and mechanical defenses.

BIOMETALS (2023)

Article Plant Sciences

BRUTUS-LIKE (BTSL) E3 ligase-mediated fine-tuning of Fe regulation negatively affects Zn tolerance of Arabidopsis

Camilla Stanton, Jorge Rodriguez-Celma, Ute Kramer, Dale Sanders, Janneke Balk

Summary: Mutation of two E3 ligases that suppress iron uptake in roots also confers tolerance to zinc toxicity, identifying a regulatory point of interaction between iron and zinc homeostasis. Loss of function of BTSL1 and BTSL2, which encode E3 ubiquitin ligases, leads to Arabidopsis thaliana having tolerance to excess zinc. These mutants have similar zinc accumulation as the wild type, but lower iron accumulation in roots.

JOURNAL OF EXPERIMENTAL BOTANY (2023)

No Data Available