Article
Multidisciplinary Sciences
Gergely Imre, Verena Kraehling, Madeleine Eichler, Sandra Trautmann, Nerea Ferreiros, M. Javad Aman, Fatah Kashanchi, Krishnaraj Rajalingam, Stefan Poehlmann, Stephan Becker, Dagmar Meyer zu Heringdorf, Josef Pfeilschifter
Summary: Research shows that activation of Sphingosine kinase 1 (SphK1) can effectively inhibit Ebola virus entry into cells and reduce viral production.
Article
Business
Shengming Liu, Ning Li, Mingya Xu
Summary: This research challenges the prevailing assumption that self-sacrificing leadership is always beneficial and demonstrates its dual effects on team prosocial and change-oriented behaviors. The study provides a nuanced model that examines the indirect positive effect of self-sacrificial leadership on team helping and the indirect negative effect on team change-oriented behaviors through unique mechanisms.
JOURNAL OF MANAGEMENT
(2022)
Article
Multidisciplinary Sciences
Luis J. Perez-Valencia, Kevin M. Vannella, Marcos J. Ramos-Benitez, Junfeng Sun, Mones Abu-Asab, David W. Dorward, Keytam S. Awad, Andrew Platt, Eliana Jacobson, Jason Kindrachuk, Daniel S. Chertow
Summary: Lymphocyte depletion is a key feature of Ebola virus disease, and shed GP, the ectodomain of EBOV glycoprotein, can induce death of B, NK, and T cells. B and NK cells are more susceptible, and the cytotoxic effect starts within 4-5 hours. Shed GP-induced lymphocyte death can occur through caspase-dependent and caspase-independent mechanisms.
Article
Green & Sustainable Science & Technology
Teresa Sanz, Beatriz Rodriguez-Labajos
Summary: This paper analyzes the impact of creative actions on the relational values in the socio-spatial restoration of Quintero and Puchuncavi communities in Chile, revealing the significance of art in interpersonal relations and socio-spatial transformations.
SUSTAINABILITY SCIENCE
(2023)
Article
Cell Biology
Jun Liu, John C. Trefry, April M. Babka, Christopher W. Schellhase, Kayla M. Coffin, Janice A. Williams, Jo Lynne W. Raymond, Paul R. Facemire, Taylor B. Chance, Neil M. Davis, Jennifer L. Scruggs, Franco D. Rossi, Andrew D. Haddow, Justine M. Zelko, Sandra L. Bixler, Ian Crozier, Patrick L. Iversen, Margaret L. Pitt, Jens H. Kuhn, Gustavo Palacios, Xiankun Zeng
Summary: Persistent Ebola virus infection in the brain ventricular system can occur in macaque survivors after therapeutic treatment, leading to severe tissue damage and inflammation.
SCIENCE TRANSLATIONAL MEDICINE
(2022)
Article
Gerontology
Miranda Corpora
Summary: All individuals should have an equitable opportunity to achieve a good death, but access to end-of-life care is often unequal based on social identities. Understanding how marginalized individuals face different access and taking steps towards equity is crucial.
Article
Geriatrics & Gerontology
Md Razib Mamun, Yoshihisa Hirakawa, K. M. Saif-Ur-Rahman, Young Jae Hong, Zean Song, Yuko Yoshida, Hiroshi Yatsuya
Summary: This study explores the perception of multiple stakeholders on a good death for people living with dementia. The findings reveal that a good death is viewed as a process rather than a single event, involving painless death, dying in a preferred environment, family's coping with loss, maintaining regular life, living with respect, and preparation for death.
Review
Neurosciences
Krishnan Ganapathy
Summary: This communication reviews the literature on good death and discusses how changes in approaches to good death in the COVID-19 era may impact neurological practice. The author's experience in neurological practice leads them to conclude that ensuring a good death should also be part of neurologic practice.
Review
Medicine, General & Internal
Jinnan Xiao, Jinfeng Ding, Chongmei Huang
Summary: This study aims to explore the views of cancer patients on a good death and identify their common values and preferences at the end of life. The findings have the potential to inform clinical care guidelines and shared decision-making in palliative care practice.
Article
Education, Scientific Disciplines
Pauline Catherine Gillan, Sarah Jeong, Pamela van der Riet
Summary: This study explores undergraduate nursing students' personal and professional experiences with death and dying in clinical practice, revealing that students' experiences are shaped by others, especially experienced nurses. Good death experiences are often influenced by nurses who guide students, while bad death experiences are influenced by undignified care and environmental factors.
NURSE EDUCATION TODAY
(2021)
Article
Multidisciplinary Sciences
Pawapol Keratichewanun, Nisachol Dejkriengkraikul, Chaisiri Angkurawaranon, Kanokporn Pinyopornpanish, Lalita Chutarattanakul, Nopakoon Nantsupawat, Nutchar Wiwatkunupakarn, Wichuda Jiraporncharoen
Summary: A 'good death' is subjective and can vary among individuals. From the perspectives of patients, caregivers, and healthcare providers, a good death is characterized by peaceful progression, symptom control, acceptance, dignity, social support, and faith. To achieve a good death, supportive care, effective communication, and honoring the patient's wishes are essential.
Correction
Medicine, General & Internal
P. Mbala-Kingebeni
Summary: This article highlights that a misspelled surname of one of the authors has affected the content about Ebola virus transmission.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Medicine, General & Internal
Placide Mbala-Kingebeni, Catherine Pratt, Mbusa Mutafali-Ruffin, Matthias G. Pauthner, Faustin Bile, Antoine Nkuba-Ndaye, Allison Black, Eddy Kinganda-Lusamaki, Martin Faye, Amuri Aziza, Moussa M. Diagne, Daniel Mukadi, Bailey White, James Hadfield, Karthik Gangavarapu, Nella Bisento, Donatien Kazadi, Bibiche Nsunda, Marceline Akonga, Olivier Tshiani, John Misasi, Aurelie Ploquin, Victor Epaso, Emilia Sana-Paka, Yannick Tutu Tshia N'kasar, Fabrice Mambu, Francois Edidi, Meris Matondo, Junior Bula Bula, Boubacar Diallo, Mory Keita, Marie R. D. Belizaire, Ibrahima S. Fall, Abdoulaye Yam, Sabue Mulangu, Anne W. Rimion, Elias Salfati, Ali Torkamani, Marc A. Suchard, Ian Crozier, Lisa Hensley, Andrew Rambaut, Ousmane Faye, Amadou Sall, Nancy J. Sullivan, Trevor Bedford, Kristian G. Andersen, Michael R. Wiley, Steve Ahuka-Mundeke, Jean-Jacques Muyembe Tamfum
Summary: During the Ebola virus disease outbreak in the Democratic Republic of Congo, a young man developed EVD, recovered after receiving monoclonal antibody treatment, but later experienced a relapse, transmitted the virus, and ultimately died.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Immunology
Chengjing Zhou, Ting Jiang, Yajie Xiao, Qiaoxuan Wang, Zhifan Zeng, Peiqiang Cai, Yongtian Zhao, Zhikun Zhao, Dongfang Wu, Hanqing Lin, Chao Sun, Rong Zhang, Weiwei Xiao, Yuanhong Gao
Summary: The study demonstrated the efficacy and safety of chemoradioimmunotherapy with PD-1 inhibitors in advanced dMMR/MSI-H CRC patients, showing that this treatment approach is effective and safe for the patients. Further research is needed to explore the potential role and mechanism of this therapy in this population.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Geography
Emma Roe, Beth Greenhough
Summary: Laboratory animal science involves deliberate and inadvertent harming and killing of animals, which has raised ethical concerns and regulation in the UK. This paper discusses the care work in laboratory animal research, including the required skills and sensitivities, the role of previous experiences, the influence of institutional and affective environments, and experiences of killing. The authors argue for a greater articulation of the coexistence of care and harms in debates about care and human-animal relations in geography.
SOCIAL & CULTURAL GEOGRAPHY
(2023)
