Article
Cardiac & Cardiovascular Systems
Jason Coult, Betty Y. Yang, Heemun Kwok, J. Nathan Kutz, Patrick M. Boyle, Jennifer Blackwood, Thomas D. Rea, Peter J. Kudenchuk
Summary: This study developed an ECG-based algorithm that can predict patients with refractory ventricular fibrillation (VF). The algorithm has shown high predictive accuracy, which can help rescuers take targeted interventions in advance and improve the resuscitation outcome.
Article
Critical Care Medicine
Tasuku Matsuyama, Kosuke Kiyohara, Tetsuhisa Kitamura, Chika Nishiyama, Takeyuki Kiguchi, Taku Iwami
Summary: This study aimed to investigate the impact of COVID-19 on public-access defibrillation (PAD) and outcomes of out-of-hospital cardiac arrests (OHCA). The results showed a decrease in the proportion of patients receiving PAD after the COVID-19 pandemic, while there was no significant reduction in favorable neurological outcomes.
Article
Cardiac & Cardiovascular Systems
Katarina Hogh Mottlau, Linn Charlotte Andelius, Rasmus Gregersen, Carolina Malta Hansen, Fredrik Folke
Summary: The study found that citizen responders were more likely to accept calls during the evening and weekends, with the highest proportion of responders arriving before the emergency medical services in the evening. However, there was no significant difference in the implementation of bystander cardiopulmonary resuscitation or early defibrillation among cases where citizen responders arrived before the emergency medical services.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Cardiac & Cardiovascular Systems
Francesca Romana Gentile, Lars Wik, Elisabete Aramendi, Enrico Baldi, Iraia Isasi, Jon Erik Steen-Hansen, Sara Compagnoni, Alessandro Fasolino, Enrico Contri, Alessandra Palo, Roberto Primi, Sara Bendotti, Alessia Currao, Simone Savastano
Summary: Antiarrhythmic drugs are recommended for shock-refractory ventricular fibrillation (VF) in out of hospital cardiac arrest (OHCA). Amplitude Spectral Area (AMSA) of VF is a predictor of shock efficacy and an emerging indicator to guide defibrillation and resuscitation efforts. However, it is unknown how AMSA might be influenced by amiodarone administration.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Sebastian Wolfrum, Kevin Roedl, Alexia Hanebutte, Rudiger Pfeifer, Volkhard Kurowski, Reimer Riessen, Anne Daubmann, Stephan Braune, Gerold Soffker, Eric Bibiza-Freiwald, Karl Wegscheider, Heribert Schunkert, Holger Thiele, Stefan Kluge
Summary: This study found that hypothermic temperature control after IHCA did not improve survival nor functional outcome. The study may have been underpowered to detect clinically important differences between hypothermic temperature control and normothermia.
Article
Critical Care Medicine
Laura Sarkisian, Hans Mickley, Henrik Schakow, Oke Gerke, Simon Michael Starck, Jonas Junghans Jensen, Jacob Eifer Moller, Gitte Jorgensen, Finn Lund Henriksen
Summary: The study evaluated and compared survival rates after OHCA in densely, moderately, and thinly populated areas where AEDs were used. It was found that the distance of AED retrieval was correlated with reduced survival rates, regardless of population density.
Article
Medicine, General & Internal
Francesca R. R. Gentile, Lars Wik, Iraia Isasi, Enrico Baldi, Elisabete Aramendi, Jon Erik Steen-Hansen, Alessandro Fasolino, Sara Compagnoni, Enrico Contri, Alessandra Palo, Roberto Primi, Sara Bendotti, Alessia Currao, Federico Quilico, Luca Vicini Scajola, Clara Lopiano, Simone Savastano
Summary: The optimal energy level for defibrillation in out-of-hospital cardiac arrest patients has not been determined. This study found that the amplitude spectral area (AMSA) of ventricular fibrillation (VF) can predict the success of low energy defibrillation. By retrospectively analyzing patient data, it was discovered that AMSA values are associated with the probability of low-energy shock success.
INTERNAL AND EMERGENCY MEDICINE
(2023)
Article
Emergency Medicine
Kwok Fung Sun, Kin Ming Poon, Chun Tat Lui, Kwok Leung Tsui
Summary: A clinical prediction rule of termination of resuscitation for out-of-hospital cardiac arrest patients with pre-hospital defibrillation was derived from a retrospective multicenter cohort study. The rule includes EMS call to ED time and ETCO2 level as independent predictors for predicting death before ED arrival. When both criteria are met, there is a high specificity and positive predictive value for predicting death before ED arrival in OHCA patients with pre-hospital defibrillation.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Medicine, General & Internal
Anton Frueh, Andrea Bileck, Besnik Muqaku, Raphael Wurm, Benjamin Neuditschko, Henrike Arfsten, Lukas Galli, Lukas Kriechbaumer, Pia Hubner, Georg Goliasch, Gottfried Heinz, Michael Holzer, Fritz Sterz, Christopher Adlbrecht, Christopher Gerner, Klaus Distelmaier
Summary: This study aimed to analyze the predictive value of the antioxidant enzyme catalase for mortality in out-of-hospital cardiac arrest survivors. It was found that high plasma levels of catalase were significantly associated with increased 30-day mortality, suggesting that ROS-dependent tissue damage plays a crucial role in fatal outcomes of post-cardiac syndrome patients.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Christian Gantzel Nielsen, Fredrik Folke, Linn Andelius, Carolina Malta Hansen, Ulla Vaeggemose, Erika Frischknecht Christensen, Christian Torp-Pedersen, Annette Kjaer Ersboll, Mads Christian Tofte Gregers
Summary: The aim of this study was to investigate the association between alarm acceptance by volunteer responders, bystander intervention, and survival in out-of-hospital cardiac arrest. The study found that when volunteer responders accepted the alarm and arrived before EMS, there was a significant increase in bystander CPR and defibrillation. This finding is important for improving the survival of out-of-hospital cardiac arrest patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Critical Care Medicine
Jonathan C. Elmer, Michael C. J. Kurz, Patrick J. Coppler, Alexis Steinberg, Stephanie DeMasi, Maria De-Arteaga, Noah I. Simon, Vladimir I. L. Zadorozhny, Katharyn L. W. Flickinger, Clifton W. Callaway
Summary: Withdrawal of life-sustaining therapies for perceived poor neurologic prognosis (WLST-N) is common after resuscitation from cardiac arrest and may bias outcome estimates from models trained using observational data. This study compares different approaches to outcome prediction with the goal of identifying strategies to quantify and reduce this bias.
CRITICAL CARE MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Ryo Emoto, Mitsuaki Nishikimi, Muhammad Shoaib, Kei Hayashida, Kazuki Nishida, Kazuya Kikutani, Shinichiro Ohshimo, Shigeyuki Matsui, Nobuaki Shime, Taku Iwami
Summary: This study aimed to predict spontaneous rhythm change before hospital arrival in patients with out-of-hospital cardiac arrest. Seven factors were identified as predictors and a scoring system was developed and validated.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Cardiac & Cardiovascular Systems
Jens Agerstrom, Magnus Carlsson, Anders Bremer, Johan Herlitz, Johan Israelsson, Kristofer Arestedt
Summary: This study revealed clear socioeconomic status differences in treatment and survival following in-hospital cardiac arrest, with higher SES patients being more likely to receive and survive emergency measures. This suggests that patients with low SES might be subject to discrimination.
EUROPEAN HEART JOURNAL
(2021)
Article
Critical Care Medicine
Johannes Grand, Christian Hassager, Henrik Schmidt, Simon Molstrom, Benjamin Nyholm, Henrik Frederiksen Hoigaard, Jordi S. Dahl, Martin Meyer, Rasmus P. Beske, Laust Obling, Jesper Kjaergaard, Jacob E. Moller
Summary: This study assessed the association between cardiac index (CI) and mixed venous oxygen saturation (SvO2) with outcomes in comatose patients resuscitated from out-of-hospital cardiac arrest (OHCA). The results showed that lower SvO2 and a combination of lower CI and lower SvO2 were associated with increased risk of mortality and renal failure.
Article
Critical Care Medicine
Sang-Beom Jeon, Hyunjo Lee, Bobin Park, Soh Hyun Choi, Yoon-Hee Hong, Won Young Kim, Sang-Bum Hong, Young-Hak Kim
Summary: Among patients with IHCA, awakening and neurological recovery were remarkable throughout the first week. Survival and good neurological status were substantial at 12 months after IHCA.