Heparanase released from mesenchymal stem cells activates integrin beta1/HIF-2alpha/Flk-1 signaling and promotes endothelial cell migration and angiogenesis

Heparanase induces inflammatory cell recruitment in vivo by promoting adhesion to vascular endothelium

(2014) Rebecca Lever et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The potential of heparanase as a therapeutic target in cancer

(2014) Claudio Pisano et al.   BIOCHEMICAL PHARMACOLOGY

Sphingosine kinase 1 expressed by endothelial colony-forming cells has a critical role in their revascularization activity

(2014) Stéphane Poitevin et al.   CARDIOVASCULAR RESEARCH

Activated PAR-2 Regulates Pancreatic Cancer Progression through ILK/HIF-α–Induced TGF-α Expression and MEK/VEGF-A–Mediated Angiogenesis

(2013) Li-Hsun Chang et al.   AMERICAN JOURNAL OF PATHOLOGY

CXXC5 is a transcriptional activator of Flk-1 and mediates bone morphogenic protein-induced endothelial cell differentiation and vessel formation

(2013) Hyun-Yi Kim et al.   FASEB JOURNAL

The Role of Prolyl Hydroxylase Domain Protein (PHD) during Rosiglitazone-induced Adipocyte Differentiation

(2013) Juyoung Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of ARNT severely compromises endothelial cell viability and function in response to moderate hypoxia

(2012) Yu Han et al.   ANGIOGENESIS

Glioblastoma-derived Tumor Cells Induce Vasculogenic Mimicry through Flk-1 Protein Activation

(2012) Ralph Francescone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heparanase-Induced GEF-H1 Signaling Regulates the Cytoskeletal Dynamics of Brain Metastatic Breast Cancer Cells

(2012) Lon D. Ridgway et al.   MOLECULAR CANCER RESEARCH

Therapeutic potential for mesenchymal stem cell transplantation in critical limb ischemia

(2012) Aaron Liew et al.   Stem Cell Research & Therapy

Increased expression of pigment epithelium-derived factor in aged mesenchymal stem cells impairs their therapeutic efficacy for attenuating myocardial infarction injury‡

(2011) Hongliang Liang et al.   EUROPEAN HEART JOURNAL

Heparanase-mediated Loss of Nuclear Syndecan-1 Enhances Histone Acetyltransferase (HAT) Activity to Promote Expression of Genes That Drive an Aggressive Tumor Phenotype

(2011) Anurag Purushothaman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immunohistochemical study of the growth factors, aFGF, bFGF, PDGF-AB, VEGF-A and its receptor (Flk-1) during arteriogenesis

(2010) Song Wu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

VEGF receptor trafficking in angiogenesis: Figure 1

(2009) Alice Scott et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia

(2009) H.-Y. Fang et al.   BLOOD

Cell surface heparan sulfate released by heparanase promotes melanoma cell migration and angiogenesis

(2009) Madhuchhanda Roy et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia

(2009) Anne Limbourg et al.   Nature Protocols

Anthracycline chemotherapy inhibits HIF-1 transcriptional activity and tumor-induced mobilization of circulating angiogenic cells

(2009) K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heparanase: busy at the cell surface

(2009) Liat Fux et al.   TRENDS IN BIOCHEMICAL SCIENCES

Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase

(2008) Ian M. Evans et al.   CELLULAR SIGNALLING

Selective induction of integrin β1 by hypoxia-inducible factor: implications for wound healing

(2008) Simon Keely et al.   FASEB JOURNAL

Sildenafil-mediated neovascularization and protection against myocardial ischaemia reperfusion injury in rats: role of VEGF/angiopoietin-1

(2008) Srikanth Koneru et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis

(2008) Xinyang Hu et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Constitutive Expression of HIF-1α and HIF-2α in Bone Marrow Stromal Cells Differentially Promotes Their Proangiogenic Properties

(2008) Jeremy Ben-Shoshan et al.   STEM CELLS

Protein kinase C   promotes angiogenic activity of human endothelial cells via induction of vascular endothelial growth factor

(2007) H. Xu et al.   CARDIOVASCULAR RESEARCH