Article
Public, Environmental & Occupational Health
Bretton Gilmore, Kelly Reveles, Christopher R. Frei
Summary: Vaping among adolescents is a growing concern that requires further research to evaluate its risks and understand the motivations behind it. This knowledge can then be used to develop effective educational and public health programs to prevent and reduce vaping among youths.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Psychology, Biological
Prashant Loyalka, Ou Lydia Liu, Guirong Li, Elena Kardanova, Igor Chirikov, Shangfeng Hu, Ningning Yu, Liping Ma, Fei Guo, Tara Beteille, Namrata Tognatta, Lin Gu, Guangming Ling, Denis Federiakin, Huan Wang, Saurabh Khanna, Ashutosh Bhuradia, Zhaolei Shi, Yanyan Li
Summary: This large-scale study reveals significant differences in skill levels and gains among university students in China, India, Russia and the United States, particularly in the STEM fields. Despite substantial investments in STEM education in these countries, students show varying levels of critical thinking and academic skill development.
NATURE HUMAN BEHAVIOUR
(2021)
Article
Obstetrics & Gynecology
Jeremy D. Lai, Richard J. Fantus, Andrew J. Cohen, Vivian Wan, Matthew T. Hudnall, Minh Pham, Robert E. Brannigan, Joshua A. Halpern
Summary: The study examined infertility-related fund-raising campaigns on a popular crowdfunding website and compared campaign characteristics across states with and without legislative mandates for insurance coverage for infertility-related care. Results showed a substantial unmet financial burden for infertility care, with states with insurance mandates having fewer crowdfunding campaigns per capita. This data can inform future health policy legislation to assist with the financial burden of infertility.
FERTILITY AND STERILITY
(2021)
Article
Obstetrics & Gynecology
Emily R. Smith, William M. Curtin, Kevin P. Yeagle, Nurgul Carcacki-Salli, Serdar H. Ural
Summary: This study aimed to determine the feasibility of identifying and quantifying mesenchymal stem cells (MSCs) from umbilical cord blood (UCB) after delayed cord clamping in preterm and term births. The results showed that MSCs were successfully identified in UCB samples obtained after delayed cord clamping in both preterm and term births, with no significant difference in MSC numbers between the two groups.
REPRODUCTIVE SCIENCES
(2023)
Review
Public, Environmental & Occupational Health
Dara D. Mendez, Jewel Scott, Linda Adodoadji, Christina Toval, Monica McNeil, Mahima Sindhu
Summary: Racism in the United States is considered a key driver of racial health inequities, with many policies naming racism as critical in addressing racial inequities in health, but with limited details on specific actions, funding, or resources.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Immunology
Cong Zeng, Yan Chen, Juan Hua, Yi Liu, Ting-ting Cheng, Xia Ma, Xu Chen, Shi-yu Wang, Ya-jing Xu
Summary: This retrospective study analyzed the outcomes of 80 patients with hematologic malignancies who received haploidentical peripheral blood stem cell transplantation (haplo-PBSCT) combined with unrelated cord blood (UCB). Satisfactory results were obtained with high engraftment rates and relatively low rates of transplant-related complications.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Ines Serrenho, Miguel Rosado, Alexandra Dinis, Carla M. Cardoso, Mario Graos, Bruno Manadas, Graca Baltazar
Summary: Neonatal hypoxic-ischemic encephalopathy is a significant cause of mortality and morbidity in the perinatal period, and therapeutic hypothermia is the standard care; however, stem cell therapy shows potential to become the next therapeutic approach, with preclinical studies reporting significant improvement in cognitive function and brain damage in HIE patients. Further research is needed to explore the combination of therapeutic hypothermia and stem cell therapy for HIE.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Cell & Tissue Engineering
Lindsay Zhou, Courtney McDonald, Tamara Yawno, Graham Jenkin, Suzanne Miller, Atul Malhotra
Summary: Cell therapies using umbilical cord blood and cord tissue have emerged as a promising approach for preventing and treating neonatal morbidities. Published clinical studies mainly focus on safety and feasibility, with limited assessment of efficacy. There are ongoing trials investigating the potential of these therapies in neonates.
STEM CELLS TRANSLATIONAL MEDICINE
(2022)
Review
Cell & Tissue Engineering
Gabriela Sanchez-Petitto, Katayoun Rezvani, May Daher, Hind Rafei, Partow Kebriaei, Elizabeth J. Shpall, Amanda Olson
Summary: Umbilical cord blood transplantation is an attractive alternative source of hematopoietic stem cells, with unique immune tolerance and engraftment kinetics. It has a lower risk of GvHD and comparable clinical outcomes to bone marrow transplantation. However, limitations in cell numbers and delayed engraftment pose challenges for its wider application. Research is being conducted to address these limitations and explore the potential of cord blood in treating various disorders.
STEM CELLS TRANSLATIONAL MEDICINE
(2023)
Article
Cell & Tissue Engineering
Huangfan Xie, Zhongjie Sun, Xiong Xiao, Defang Liu, Hailong Qi, Guoxiong Tian, Miao Chen, Ligong Chen, Xuncheng Su
Summary: Transient inhibition of the JNK pathway can increase the frequency of HSCs in cord blood and promote their quiescence, leading to the enhancement of HSC number and engraftment potential. These findings have the potential to improve HSC collection and transplantation.
STEM CELLS TRANSLATIONAL MEDICINE
(2022)
Article
Psychology, Developmental
Beidi Dong, David B. Wilson
Summary: This study examines the association between state firearm legislation and youth/young adult handgun carrying in the United States and identifies policy priority areas for intervention. The findings suggest that states with a greater number of gun policies have lower rates of handgun carrying among youth and young adults. Regulations on gun purchasing, concealed carrying permitting, and domestic violence-related laws are particularly effective in reducing gun-carrying behavior. Moreover, these associations vary by gender and race/ethnicity.
JOURNAL OF ADOLESCENT HEALTH
(2022)
Article
Chemistry, Multidisciplinary
Yong Xie, Yi Sun, Yudong Liu, Jinyun Zhao, Quanbo Liu, Jiaqi Xu, Yiming Qin, Rundong He, Feifei Yuan, Tianding Wu, Chunyue Duan, Liyuan Jiang, Hongbin Lu, Jianzhong Hu
Summary: This study explores a specific targeted treatment approach for spinal cord injury by identifying stable subpopulations of exosomes that can improve blood-spinal cord barrier integrity and promote neural function recovery.
Article
Social Sciences, Interdisciplinary
Ted Peterson, Zachary Bair
Summary: American politicians aim to expand the economy and provide opportunities for citizens through creating economic activities. This research examines the impacts of tax and other economic variables on economic wellbeing, providing a timely update on contributing factors to economic growth. The study finds that increases in the highest statutory corporate and personal income tax rates reduce real GDP per capita, while growth in net exports of goods and services, M2 money supply, multifactor productivity and cost increase real GDP per capita.
Article
Cell & Tissue Engineering
Monique Joris, Katie Paulson, Lesa Foley, Merry Duffy, Sergio Querol, Susana Gomez, Etienne Baudoux
Summary: The survey indicates that the majority of public cord blood banks worldwide are up to standard in terms of technical procedures. There is a need for improvement in accreditation, standardization of testing, and setting of thresholds for accepting CBUs.
STEM CELLS TRANSLATIONAL MEDICINE
(2021)
Article
Environmental Studies
Yiran Bai, Shichao Tang, Chunxian Lu, Beier Chen, Minghui Yan
Summary: In households with high uncertainty, consumption is likely to be reduced, credit access is available more easily, and equity market investments are less likely to be made. Economic policy uncertainty for natural resource policy is largely ignored in the existing literature. This paper explores the impacts of economic policy uncertainty on natural resources considering the roles of financial development, inflation, and economic growth in the United States from 1985 to 2020. Our result suggests that natural resource development is discouraged by economic policy uncertainty.
Article
Engineering, Biomedical
Hyunjun Choi, Bongseo Choi, Bo Yu, Weiguo Li, Monica M. Matsumoto, Kathleen R. Harris, Robert J. Lewandowski, Andrew C. Larson, Samdeep K. Mouli, Dong-Hyun Kim
Summary: The study introduces degradable and MRI-visible microspheres for embolotherapy, demonstrating their responsive on-demand degradation properties in vitro and in vivo. Successful embolization of hepatic arteries with these microspheres under DSA guidance was confirmed with images and contrast-enhanced MRI. The T2 MRI visibility of these microspheres allowed for monitoring their distribution during intra-arterial infusion.
Article
Medicine, General & Internal
Khalid A. Kheirallah, Fayez Abdulrazeq, Abdallah Alzoubi, Jomana W. Alsulaiman, Nasr Alrabadi, Mahmoud A. Alfaqih, Mazhar S. Al Zoubi, Monica M. Matsumoto
Summary: This study reveals that physicians in Jordan have a low/moderate level of overall stem cell knowledge, but their attitudes towards stem cell research and therapies are positive. Male physicians reported significantly more knowledge than females. There is a need for more stem cell-related information to be included in medical curricula in Jordan.
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
(2021)
Article
Cell & Tissue Engineering
Zubin Master, Kirstin R. W. Matthews, Mohamed Abou-el-Enein
Summary: The unproven stem cell intervention industry is a global health issue that requires a coordinated global approach through the establishment of a World Health Organization Expert Advisory Committee on Regenerative Medicine to address regulations, regulatory approaches, and education campaigns. Fostering international dialogues and developing recommendations that can be adopted by member states would effectively tackle the global market of unproven SCIs.
Article
Radiology, Nuclear Medicine & Medical Imaging
I. M. Gonzalez Moreno, J. Trejo-Falcon, M. M. Matsumoto, M. Huertas Moreno, M. Martinez Galvez, G. R. Farfan Quispe, F. Y. Chavez Pareja, D. J. Mollura, E. Pollackd, J. R. Scheeld, J. M. Garcia Santos
Summary: Breast cancer is the second most common cancer in Peruvian women. Due to limitations in national breast cancer screening programs, especially in rural areas, more than 50% of cases are diagnosed in advanced stages. RAD-AID International collaborates with a local non-governmental organization to establish a sustainable diagnostic structure and improve breast cancer screening in Cuzco. With the support of local, national, and international partners, they have trained local clinic staff and provided additional training for radiology residents through international collaboration.
Letter
Radiology, Nuclear Medicine & Medical Imaging
Monica M. Matsumoto, Robert Dixon, Kevin Anton, Stephen J. Hunt, Andrew Kesselman
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Monica M. Matsumoto, Shilpa N. Reddy, Gregory J. Nadolski, Susan Shamimi-Noori, Scott O. Trerotola, S. William Stavropoulos
Summary: The purpose of this study was to evaluate differences in arteriographic findings and outcomes after embolization among patients with a suspected iatrogenic renal arterial injury (IRAI). The results showed that arteriographic findings and outcomes were similar among patients who underwent partial nephrectomy, biopsy, or percutaneous access. Prearteriographic imaging can help identify IRAIs, but clinical judgment regarding embolization indication is still necessary. IRAIs can occur acutely or after a long interval, with biopsy patients presenting earlier and requiring more blood transfusions. IRAIs can be treated with embolization without permanent deleterious effects on renal function.
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Monica M. Matsumoto, S. William Stavropoulos, Scott O. Trerotola
Summary: This study evaluated the use of the grasp-and-fold technique for complex forceps retrieval of inferior vena cava (IVC) filters. Retrospective study of 14 patients with deeply tip-embedded or severely distorted IVC filters was performed, and the grasp-and-fold technique successfully removed all filters with mild to moderate adverse events occurring.
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Monica M. Matsumoto, Susan Shamimi-Noori, Terence P. Gade, Jason C. Hoffmann, Gregory J. Nadolski, Daniel M. DePietro
Summary: This study characterizes the experiences of matched applicants and program directors in the 2022 interventional radiology residency match and compares the data with that of 2017. The results show similar demographic traits among participants and overall satisfaction with the match outcomes. Compared to 2017, applicants applied to more programs and prioritized research and publications more than program directors. Virtual interviews were convenient and accessible but also led to overinterviewing.
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Damien Medrano, Monica M. Matsumoto, Efren Flores, Farouk Dako
Summary: Although seen as a social construct, race is still considered a genetic marker in the medical field, influencing the interpretation of test results and leading to inequitable care. This false premise is also present in radiology, impacting the entire practice. This review explores historical perspectives, implicated scenarios, and mitigation strategies.
JOURNAL OF THE AMERICAN COLLEGE OF RADIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Monica M. Matsumoto, Daniel Picus, Scott O. Trerotola
Summary: This study provides practical and technical tips for adrenal vein sampling (AVS) in the presence of left renal vein (LRV) variants. The authors identify different LVR variants and their impact on AVS, and suggest specific approaches for catheterization in each variant.
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Letter
Radiology, Nuclear Medicine & Medical Imaging
Monica M. Matsumoto, Gregory J. Nadolski
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Review
Cell & Tissue Engineering
Ana S. Iltis, Grace Koster, Emily Reeves, Kirstin R. W. Matthews
Summary: Recent advances in pluripotent stem cell culture have led to the development of entities, known as embryoids, which closely resemble advanced stages of early embryo development. A systematic review of literature from 2016 to 2022 identified four categories of ethical, legal, regulatory, and policy considerations in human embryoid research: research justifications/benefits, ethical significance or moral status, permissible use, and regulatory and oversight challenges. Analyzing these issues is crucial for advancing ethical and regulatory frameworks in this emerging field.
STEM CELL RESEARCH & THERAPY
(2023)
Article
Ethics
Kirstin R. W. Matthews, Daniel Morali
Summary: Recent technological advances have improved the understanding of early human development, but conflicts arise with national and state policies in the USA. Federal and state laws impact human embryo and embryoid research, creating a complex landscape. Additional national guidance is needed to navigate the controversial areas of research.
JOURNAL OF LAW AND THE BIOSCIENCES
(2022)
Review
International Relations
Ana S. Iltis, Sarah Hoover, Kirstin R. W. Matthews
Summary: As scientific research continues to push boundaries, new discoveries and technologies bring about ethical and social questions, sparking varying public responses. The use of precise gene editing tools on human embryos, like CRISPR-Cas9, raises substantial disagreement due to deeply rooted ethical concerns tied to moral and religious beliefs. Scientists and policymakers are increasingly calling for public engagement in developing guidelines and policies for governing scientific practice.
FRONTIERS IN POLITICAL SCIENCE
(2021)
Article
Ethics
Kirstin R. W. Matthews, Ana S. Iltis, Nuria Gallego Marquez, Daniel S. Wagner, Jason Scott Robert, Inmaculada de Melo-Martin, Marieke Bigg, Sarah Franklin, Soren Holm, Ingrid Metzler, Matteo A. Mole, Jochen Taupitz, Giuseppe Testa, Jeremy Sugarman
Summary: With new technology, it is now possible to extend the culture time of human embryos beyond the previous fourteen-day limit, prompting the need for a deliberative process involving stakeholders and public outreach to reassess this carefully established restriction.
HASTINGS CENTER REPORT
(2021)