Article
Environmental Sciences
Amy E. Margolis, David Pagliaccio, Bruce Ramphal, Sarah Banker, Lauren Thomas, Morgan Robinson, Masato Honda, Tamara Sussman, Jonathan Posner, Kurunthachalam Kannan, Julie Herbstman, Virginia Rauh, Rachel Marsh
Summary: Prenatal exposure to environmental tobacco smoke may have detrimental effects on children's brain structure and function, affecting cognitive control and attention. The study results show that children exposed to ETS had smaller thalamic and inferior frontal gyrus volumes, and exhibited increased brain activation during cognitive conflict resolution.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Environmental Sciences
Xin-Chen Liu, Esben Strodl, Chuan-An Wu, Li-Hua Huang, Xiao-Na Yin, Guo-Min Wen, Deng-Li Sun, Dan-Xia Xian, Wei-Qing Chen
Summary: Maternal exposure to environmental tobacco smoke (ETS) during pregnancy significantly increases the risk of preterm birth, with the highest risk observed when exposed in the first trimester.
ENVIRONMENTAL RESEARCH
(2022)
Article
Cell Biology
Ronghua Huang, Bingbiao Lin, Hongyan Tian, Qichen Luo, Yalan Li
Summary: This study investigated the effect of prenatal exposure to esketamine on neuronal development in offspring rats using a rat model. The results showed that esketamine exposure resulted in impaired neuronal development, including shorter axon length, fewer dendrite branches, decreased proliferative capacity, and impaired neurogenesis and neuron maturity. These deficits led to compromised hippocampal function and deficits in neuronal cognition, memory, and emotion. The findings suggest that the neurobehavioral deficits due to prenatal esketamine exposure may be related to abnormalities in CREB phosphorylation and NMDA receptor subunits.
CELLULAR AND MOLECULAR NEUROBIOLOGY
(2023)
Article
Environmental Sciences
Mariah DeSerisy, Jacob W. Cohen, Jordan D. Dworkin, Jeanette A. Stingone, Bruce Ramphal, Julie B. Herbstman, David Pagliaccio, Amy E. Margolis
Summary: This study found that prenatal secondhand smoke exposure combined with early life stress could lead to increased internalizing symptoms in children during the preschool period and slower reduction of these symptoms over time. Maternal stress levels explained this association and provide guidance for personalized prevention measures.
ENVIRONMENTAL HEALTH
(2023)
Article
Neurosciences
L. N. Jenna Sprowles, L. C. Kelsey Dzwilewski, M. Francheska Merced-Nieves, M. A. Salma Musaad, L. Susan Schantz, D. Sarah Geiger
Summary: This study explored the relationship between prenatal exposure to phthalates and infant neurodevelopment, highlighting the sex- and age-specific associations between different phthalates and infant neurobehavior.
NEUROTOXICOLOGY AND TERATOLOGY
(2022)
Article
Environmental Sciences
Nadya Y. Rivera Rivera, Marcela Tamayo-Ortiz, Adriana Mercado Garcia, Allan C. Just, Itai Kloog, Martha Maria Tellez-Rojo, Robert O. Wright, Rosalind J. Wright, Maria Jose Rosa
Summary: Exposure to prenatal ETS modified the association between prenatal and early life PM2.5 exposure and respiratory outcomes at age 6-8 years, suggesting the importance of considering concurrent chemical exposures to more comprehensively characterize children's environmental risk. Interventions aimed at decreasing passive smoking might mitigate the effects of ambient air pollution.
ENVIRONMENTAL RESEARCH
(2021)
Article
Environmental Sciences
Victoria Fruh, Sheryl L. Rifas-Shiman, Brent A. Coull, Katrina L. Devick, Chitra Amarasiriwardena, Andres Cardenas, David C. Bellinger, Lauren A. Wise, Roberta F. White, Robert O. Wright, Emily Oken, Birgit Claus Henn
Summary: The study found associations between prenatal exposure to lead and selenium with increased neurobehavioral ratings in children, without evidence of interactions between other elements. Although the associations were small, there may be dose-dependent impacts observed with limited exposure levels within the population.
ENVIRONMENTAL RESEARCH
(2021)
Article
Obstetrics & Gynecology
K. K. Venkatesh, A. Leviton, R. N. Fichorova, R. M. Joseph, L. M. Douglass, J. A. Frazier, K. C. K. Kuban, H. P. Santos, R. C. Fry, T. M. O'Shea
Summary: Prenatal tobacco smoke exposure was associated with an increased risk of epilepsy at 10 years of age among children born extremely preterm, but not with other neurological impairments.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2021)
Article
Environmental Sciences
Zhenzhen Xie, Jing Tan, Guanghong Fang, Honglei Ji, Maohua Miao, Yuan Tian, Hui Hu, Wencheng Cao, Hong Liang, Wei Yuan
Summary: Findings from this study suggest that prenatal exposure to multiple PFASs may have some effects on neurobehavioral development in children, but there is no clear evidence of negative effects. However, the modest associations found still suggest the potential developmental neurotoxicity of prenatal PFAS exposure.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Environmental Sciences
Xianghua Bao, Amin Asgari, Moslem Lari Najafi, Adel Mokammel, Mohammad Ahmadi, Sajjad Akbari, Mohammad Miri
Summary: The study found that physical activity and healthy diet are associated with lower blood heavy metal concentrations in WP smokers, but further research is needed to confirm this finding.
ENVIRONMENTAL RESEARCH
(2021)
Article
Medicine, General & Internal
Li-Zi Lin, Shu-Li Xu, Qi-Zhen Wu, Yang Zhou, Hui-Min Ma, Duo-Hong Chen, Gong-Bo Chen, Hong-Yao Yu, Bo-Yi Yang, Xiao-Wen Zeng, Li-Wen Hu, Guang-Hui Dong
Summary: The study found that children exposed to secondhand smoke from pregnancy to childhood are more likely to experience attention-deficit/hyperactivity disorder, especially when exposed during the prenatal and early postnatal periods. This highlights the importance of reducing secondhand smoke exposure in order to alleviate the health and economic burden on individuals with ADHD.
Article
Pediatrics
Bernard F. Fuemmeler, Trevin E. Glasgow, Julia C. Schechter, Rachel Maguire, Yaou Sheng, Tatyana Bidopia, D. Jeremy Barsell, Albert Ksinan, Junfeng Zhang, Yan Lin, Cathrine Hoyo, Susan Murphy, Jian Qin, Xiangtian Wang, Scott Kollins
Summary: This study examines the relationship between prenatal and childhood smoke exposure and neurodevelopmental and behavioral problems in early childhood. The results show that childhood smoke exposure is associated with poorer cognitive performance, language development, and attention regulation. However, the association between childhood smoke exposure and attention problems becomes nonsignificant after adjusting for confounders. There was no significant association found for maternal smoke exposure, but an interaction was detected between prenatal and childhood smoke exposure on language development.
JOURNAL OF PEDIATRICS
(2023)
Article
Environmental Sciences
Marta Szukalska, Thurman Allen Merritt, Wiktor Lorenc, Katarzyna Sroczynska, Izabela Miechowicz, Izabela Komorowicz, Jan Mazela, Danuta Baralkiewicz, Ewa Florek
Summary: The study compared the levels of essential and toxic metals in breast milk of smoking women, women exposed to second-hand smoke, and non-smoking women. Exposure to tobacco smoke was found to increase concentrations of heavy metals, potentially disrupting the growth and development of newborns and infants. These findings highlight the importance of educating lactating women about the risks of tobacco smoke exposure.
ENVIRONMENTAL RESEARCH
(2021)
Review
Neurosciences
Andrea L. Glenn, Leah K. Ragno, Jianghong Liu
Summary: This systematic review explores the association between postnatal ETS exposure and child conduct problems in studies that control for prenatal ETS exposure. Of the thirteen studies identified, nine reported a significant positive association of postnatal ETS exposure and child conduct-related behavior problems when controlling for prenatal ETS exposure. Results from tests of dose-response relationships were mixed. These findings highlight the significance of postnatal ETS exposure in conferring risk for conduct problems over and above prenatal ETS, and thus provide important information for guiding public health recommendations.
Article
Environmental Sciences
Amy E. Margolis, Sang Han Lee, Ran Liu, Lindsay Goolsby, Frances Champagne, Julie Herbstman, Beatrice Beebe
Summary: This study aimed to determine the influence of prenatal second hand smoke exposure on infant self-regulation. Using video recordings of 99 mothers and their 4-month-old infants, it was found that prenatal second hand smoke exposure was associated with decreased self-regulation in infants. These findings are crucial for child development.
ENVIRONMENTAL RESEARCH
(2023)