4.4 Article

Maternal self-esteem, exposure to lead, and child neurodevelopment

Journal

NEUROTOXICOLOGY
Volume 29, Issue 2, Pages 278-285

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.neuro.2007.11.006

Keywords

child; cognition; lead; neurotoxicology; mother-child relations

Funding

  1. NIEHS NIH HHS [P42 ES005947, R01 ES014930, P30 ES000002, R01 ES007821-07, P01 ES012874, R01 ES013744-01A2, R01 ES007821, P01 ES012874-030001, 2P30 ES00002, P42-ES05947, R01 ES014930-01, P01ES012874, K23 ES000381, R01 ES013744, K23ES000381] Funding Source: Medline
  2. NIMH NIH HHS [5 T32 MH073122-04, T32 MH073122-04, T32 MH073122] Funding Source: Medline
  3. PHS HHS [R01-013744] Funding Source: Medline

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The notion that maternal personality characteristics influence cognitive development in their children has been grounded in stress moderation theory. Maternal personality traits, such as self-esteem, may buffer maternal stressors or lead to improved maternal-child interactions that directly impact neurodevelopment. This can be extended to suggest that maternal personality may serve to attenuate or exacerbate the effects of other neurotoxicants, although this has not been studied directly. We examined whether mothers' self-esteem had a direct or main effect on their children's cognitive outcomes. We also explored the modifying effects of maternal self-esteem on the association between exposure to lead and neurodevelopment in these children. Study participants included 379 mother-child pairs from Mexico City. Data included the Coopersmith Self-Esteem Scale in mothers, children's Bayley's Scale of Infant Development (BSID) scores, and sociodemographic information. Linear regression was used to model the relationship between maternal self-esteem and the Bayley's Mental Development Index (MDI) and Psychomotor Development Index (PDI) scores at age 24 months using models stratified by levels of maternal self-esteem. In adjusted models, each point increase in maternal self-esteem was associated with children having 0.2 higher score on the Bayley's MDI (p = 0.04). Similar results were observed using the PDI outcome. Moreover, there was evidence that maternal self-esteem attenuated the negative effects of lead exposure, although the interaction fell short of conventional levels of statistical significance. (C) 2007 Elsevier Inc. All rights reserved.

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