3,4-Dihydroxyphenylethanol Attenuates Spatio-Cognitive Deficits in an Alzheimer’s Disease Mouse Model: Modulation of the Molecular Signals in Neuronal Survival-Apoptotic Programs

Hydroxytyrosol ameliorates oxidative stress and mitochondrial dysfunction in doxorubicin-induced cardiotoxicity in rats with breast cancer

(2014) Sergio Granados-Principal et al.   BIOCHEMICAL PHARMACOLOGY

Regulation of the biogenesis of OXPHOS complexes in cell transition from replicating to quiescent state

(2014) Anna Signorile et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Hydroxytyrosol, a natural molecule from olive oil, suppresses the growth of human hepatocellular carcinoma cells via inactivating AKT and nuclear factor-kappa B pathways

(2014) Baolei Zhao et al.   CANCER LETTERS

Signaling pathway cross talk in Alzheimer’s disease

(2014) Juan A Godoy et al.   Cell Communication and Signaling

Neuroglobin and neuronal cell survival

(2013) Marco Fiocchetti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Toxicological evaluation of pure hydroxytyrosol

(2013) David Auñon-Calles et al.   FOOD AND CHEMICAL TOXICOLOGY

Hydroxytyrosol prevents diet-induced metabolic syndrome and attenuates mitochondrial abnormalities in obese mice

(2013) Ke Cao et al.   FREE RADICAL BIOLOGY AND MEDICINE

 -Amyloid Disrupts Activity-Dependent Gene Transcription Required for Memory through the CREB Coactivator CRTC1

(2013) J. Espana et al.   JOURNAL OF NEUROSCIENCE

Protective effects of hydroxytyrosol on liver ischemia/reperfusion injury in mice

(2013) Shangha Pan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Amyloid-β1–42 oligomer accelerates senescence in adult hippocampal neural stem/progenitor cells via formylpeptide receptor 2

(2013) N He et al.   Cell Death & Disease

Increasing levels of wild-type CREB up-regulates several activity-regulated inhibitor of death (AID) genes and promotes neuronal survival

(2012) Yan-Wei Tan et al.   BMC NEUROSCIENCE

Hydroxytyrosol Attenuates Peripheral Neuropathy in Streptozotocin-Induced Diabetes in Rats

(2012) Giuseppe Ristagno et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Cognitive Enhancement with Rosiglitazone Links the Hippocampal PPAR  and ERK MAPK Signaling Pathways

(2012) L. A. Denner et al.   JOURNAL OF NEUROSCIENCE

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

Akebia saponin D attenuates ibotenic acid-induced cognitive deficits and pro-apoptotic response in rats: Involvement of MAPK signal pathway

(2012) Xing Yu et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

A Diet Rich in Olive Oil Phenolics Reduces Oxidative Stress in the Heart of SAMP8 Mice by Induction of Nrf2-Dependent Gene Expression

(2012) Banu Bayram et al.   REJUVENATION RESEARCH

Tyrosol and Hydroxytyrosol Two Main Components of Olive Oil, Protect N2a Cells Against Amyloid-β-Induced Toxicity. Involvement of the NF-κB Signaling

(2011) C. St-Laurent-Thibault et al.   Current Alzheimer Research

Olive polyphenol hydroxytyrosol prevents bone loss

(2011) Keitaro Hagiwara et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Enhancement of nose-to-brain delivery of basic fibroblast growth factor for improving rat memory impairments induced by co-injection of β-amyloid and ibotenic acid into the bilateral hippocampus

(2011) Chengcheng Feng et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

In Vivo Prevention of Bladder Urotoxicity

(2011) Kamel Rouissi et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

c-Jun N-terminal Kinase Regulates Soluble Aβ Oligomers and Cognitive Impairment in AD Mouse Model

(2011) Alessandra Sclip et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Huperzine a alleviates synaptic deficits and modulates amyloidogenic and nonamyloidogenic pathways in APPswe/PS1dE9 transgenic mice

(2011) Ying Wang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Oleuropein and derivatives from olives as Tau aggregation inhibitors

(2011) Anthony Daccache et al.   NEUROCHEMISTRY INTERNATIONAL

Soluble amyloid  -protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

(2011) M. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Hydroxytyrosol protects against oxidative damage by simultaneous activation of mitochondrial biogenesis and phase II detoxifying enzyme systems in retinal pigment epithelial cells

(2010) Lu Zhu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

A novel pathway regulates memory and plasticity via SIRT1 and miR-134

(2010) Jun Gao et al.   NATURE

 -Amyloid Oligomers Induce Phosphorylation of Tau and Inactivation of Insulin Receptor Substrate via c-Jun N-Terminal Kinase Signaling: Suppression by Omega-3 Fatty Acids and Curcumin

(2009) Q.-L. Ma et al.   JOURNAL OF NEUROSCIENCE

Insulin Signaling in Sporadic Alzheimer's Disease

(2009) F.-F. Liao et al.   Science Signaling

Modulatory effect of acetyl-l-carnitine on amyloid precursor protein metabolism in hippocampal neurons

(2008) Roberta Epis et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Amyloid-β causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons

(2008) T Chiba et al.   MOLECULAR PSYCHIATRY

Neuroprotective effect of hydroxytyrosol and hydroxytyrosol acetate in rat brain slices subjected to hypoxia–reoxygenation

(2008) José Antonio González-Correa et al.   NEUROSCIENCE LETTERS