Designing Clinical Trials for Dystonia

The focal dystonias: Current views and challenges for future research

(2013) H. A. Jinnah et al.   MOVEMENT DISORDERS

AFQ056 in Parkinson patients with levodopa-induced dyskinesia: 13-week, randomized, dose-finding study

(2013) Fabrizio Stocchi et al.   MOVEMENT DISORDERS

Dystonia rating scales: Critique and recommendations

(2013) Alberto Albanese et al.   MOVEMENT DISORDERS

Phenomenology and classification of dystonia: A consensus update

(2013) Alberto Albanese et al.   MOVEMENT DISORDERS

Assessment of patients with isolated or combined dystonia: An update on dystonia syndromes

(2013) Victor S. C. Fung et al.   MOVEMENT DISORDERS

Raising Orphans: How Clinical Development Programs of Drugs for Rare and Common Diseases Are Different

(2012) M Orfali et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Overview, hurdles, and future work in adaptive designs: perspectives from a National Institutes of Health-funded workshop

(2012) Christopher S Coffey et al.   Clinical Trials

Deep brain stimulation for dystonia

(2012) M. Vidailhet et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Pallidal deep brain stimulation in patients with primary generalised or segmental dystonia: 5-year follow-up of a randomised trial

(2012) Jens Volkmann et al.   LANCET NEUROLOGY

Age at onset and symptom spread in primary adult-onset blepharospasm and cervical dystonia

(2012) Davide Martino et al.   MOVEMENT DISORDERS

Adaptive trial designs: a review of barriers and opportunities

(2012) John A Kairalla et al.   Trials

The non-motor syndrome of primary dystonia: clinical and pathophysiological implications

(2011) M. Stamelou et al.   BRAIN

Statistical aspects of the TNK-S2B trial of tenecteplase versus alteplase in acute ischemic stroke: an efficient, dose-adaptive, seamless phase II/III design

(2011) Bruce Levin et al.   Clinical Trials

Nonmotor manifestations of dystonia: A systematic review

(2011) Daniel J. Kuyper et al.   MOVEMENT DISORDERS

Efficiency Perspectives on Adaptive Designs in Stroke Clinical Trials

(2011) Ken Cheung et al.   STROKE

Satisfaction with botulinum toxin treatment: a cross-sectional survey of patients with cervical dystonia

(2011) Kapil D. Sethi et al.   JOURNAL OF MEDICAL ECONOMICS

Chemical enhancement of torsinA function in cell and animal models of torsion dystonia

(2010) S. Cao et al.   Disease Models & Mechanisms

A futility study of minocycline in Huntington's disease

(2010) Merit Cudkowicz   MOVEMENT DISORDERS

Molecular pathways in dystonia

(2010) D. Cristopher Bragg et al.   NEUROBIOLOGY OF DISEASE

Pivotal studies of orphan drugs approved for neurological diseases

(2009) Jun Mitsumoto et al.   ANNALS OF NEUROLOGY

Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III

(2009) Petra Kaufmann et al.   ANNALS OF NEUROLOGY

Treatment of hyperkinetic movement disorders

(2009) Joseph Jankovic   LANCET NEUROLOGY

Clinical research for rare disease: Opportunities, challenges, and solutions

(2008) Robert C. Griggs et al.   MOLECULAR GENETICS AND METABOLISM

Relationship between various clinical outcome assessments in patients with blepharospasm

(2008) Joseph Jankovic et al.   MOVEMENT DISORDERS

Experimental therapeutics for dystonia

(2008) H. A. Jinnah et al.   Neurotherapeutics

Adaptive Clinical Trials

(2008) Christopher S Coffey et al.   Drugs in research & development