The molecular biology of WHO Grade II gliomas

Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma

(2011) Genevieve Schindler et al.   ACTA NEUROPATHOLOGICA

A Tale of Two Subunits: How the Neomorphic R132H IDH1 Mutation Enhances Production of αHG

(2011) Beth Pietrak et al.   BIOCHEMISTRY

Isocitrate dehydrogenase mutations may be a protective mechanism in glioma patients

(2011) Jian Zhu et al.   MEDICAL HYPOTHESES

BRAF V600E Mutations Are Common in Pleomorphic Xanthoastrocytoma: Diagnostic and Therapeutic Implications

(2011) Dora Dias-Santagata et al.   PLoS One

Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis

(2010) Philippe Metellus et al.   ACTA NEUROPATHOLOGICA

Molecular Classification of Low-Grade Diffuse Gliomas

(2010) Young-Ho Kim et al.   AMERICAN JOURNAL OF PATHOLOGY

IDH1 mutant structures reveal a mechanism of dominant inhibition

(2010) Shimin Zhao et al.   CELL RESEARCH

Molecular mechanisms of “off-on switch” of activities of human IDH1 by tumor-associated mutation R132H

(2010) Bei Yang et al.   CELL RESEARCH

Segregation of non-p.R132H mutations inIDH1in distinct molecular subtypes of glioma

(2010) Lonneke A.M. Gravendeel et al.   HUMAN MUTATION

The Imprinted GenePEG3Inhibits Wnt Signaling and Regulates Glioma Growth

(2010) Xiuli Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Temporal lobe pleomorphic xanthoastrocytoma and acquired BRAF mutation in an adolescent with the constitutional 22q11.2 deletion syndrome

(2010) Jeffrey C. Murray et al.   JOURNAL OF NEURO-ONCOLOGY

Cytogenetic analysis of paediatric astrocytoma using comparative genomic hybridisation and fluorescence in-situ hybridisation

(2010) Samantha J. Ward et al.   JOURNAL OF NEURO-ONCOLOGY

OLIG2 is differentially expressed in pediatric astrocytic and in ependymal neoplasms

(2010) José Javier Otero et al.   JOURNAL OF NEURO-ONCOLOGY

Distinct patterns of 1p and 19q alterations identify subtypes of human gliomas that have different prognoses†

(2010) Artemis P. Vogazianou et al.   NEURO-ONCOLOGY

Activation of the Hedgehog pathway in pilocytic astrocytomas

(2010) Sarah Z. Rush et al.   NEURO-ONCOLOGY

Anaplastic Pleomorphic Xanthoastrocytoma With a Component of Anaplastic Astrocytoma Presenting as Skull Base Tumor Followed by Downward Extracranial Extension

(2010) Satoshi TSUTSUMI et al.   NEUROLOGIA MEDICO-CHIRURGICA

All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2

(2010) M. Labussiere et al.   NEUROLOGY

Single-Copy Gain of Chromosome 1q Is a Negative Prognostic Marker in Pediatric Nonependymal, Nonpilocytic Gliomas

(2010) Tomoru. Miwa et al.   NEUROSURGERY

Pleomorphic xanthoastrocytoma in children and adolescents

(2010) Amulya A. Nageswara Rao et al.   PEDIATRIC BLOOD & CANCER

The Proneural Molecular Signature Is Enriched in Oligodendrogliomas and Predicts Improved Survival among Diffuse Gliomas

(2010) Lee A. D. Cooper et al.   PLoS One

Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma

(2009) Andrey Korshunov et al.   ACTA NEUROPATHOLOGICA

IDH1 Mutations Are Early Events in the Development of Astrocytomas and Oligodendrogliomas

(2009) Takuya Watanabe et al.   AMERICAN JOURNAL OF PATHOLOGY

Prevalence of mutated TP53 on cDNA (but not on DNA template) in pleomorphic xanthoastrocytoma with positive TP53 immunohistochemistry

(2009) Magdalena Zakrzewska et al.   CANCER GENETICS AND CYTOGENETICS

Genetic alterations and signaling pathways in the evolution of gliomas

(2009) Hiroko Ohgaki et al.   CANCER SCIENCE

Integrated molecular analysis suggests a three-class model for low-grade gliomas: A proof-of-concept study

(2009) Nicholas F. Marko et al.   GENOMICS

Isocitrate Dehydrogenase 1 Codon 132 Mutation Is an Important Prognostic Biomarker in Gliomas

(2009) Marc Sanson et al.   JOURNAL OF CLINICAL ONCOLOGY

Detection of human herpesvirus-6 variants in pediatric brain tumors: Association of viral antigen in low grade gliomas

(2009) John R. Crawford et al.   JOURNAL OF CLINICAL VIROLOGY

IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas

(2009) Koichi Ichimura et al.   NEURO-ONCOLOGY

IDH1andIDH2Mutations in Gliomas

(2009) Hai Yan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinicopathological and immunohistochemical features of three pilomyxoid astrocytomas: Comparative study with 11 pilocytic astrocytomas

(2009) Vishwa J. Amatya et al.   PATHOLOGY INTERNATIONAL

PDGF-C Induces Maturation of Blood Vessels in a Model of Glioblastoma and Attenuates the Response to Anti-VEGF Treatment

(2009) Emmanuelle di Tomaso et al.   PLoS One

Glioma-Derived Mutations in IDH1 Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1 

(2009) S. Zhao et al.   SCIENCE

Analysis of the IDH1 codon 132 mutation in brain tumors

(2008) Jörg Balss et al.   ACTA NEUROPATHOLOGICA

Genomic expression patterns distinguish long-term from short-term glioblastoma survivors: A preliminary feasibility study

(2008) Nicholas F. Marko et al.   GENOMICS

Subtelomeric analysis of pediatric astrocytoma: subchromosomal instability is a distinctive feature of pleomorphic xanthoastrocytoma

(2008) Elena Grau et al.   JOURNAL OF NEURO-ONCOLOGY

Tumor antigen precursor protein profiles of adult and pediatric brain tumors identify potential targets for immunotherapy

(2008) Jian Gang Zhang et al.   JOURNAL OF NEURO-ONCOLOGY

Gene Expression Profiling of NF-1-Associated and Sporadic Pilocytic Astrocytoma Identifies Aldehyde Dehydrogenase 1 Family Member L1 (ALDH1L1) as an Underexpressed Candidate Biomarker in Aggressive Subtypes

(2008) Fausto J. Rodriguez et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Clinicopathological features and global genomic copy number alterations of pilomyxoid astrocytoma in the hypothalamus/optic pathway: comparative analysis with pilocytic astrocytoma using array-based comparative genomic hybridization

(2008) Yoon-Kyung Jeon et al.   MODERN PATHOLOGY

Correlation of chromosomes 1p and 19q status and expressions of O6-methylguanine DNA methyltransferase (MGMT), p53 and Ki-67 in diffuse gliomas of World Health Organization (WHO) grades II and III: a clinicopathological study

(2008) L. Huang et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE

Gene expression analyses of grade II gliomas and identification of rPTPβ/ζ as a candidate oligodendroglioma marker

(2007) Daniel Hägerstrand et al.   NEURO-ONCOLOGY