Article
Clinical Neurology
Luca Jacopo Pavan, Danoob Dalili, Aldo Eros De Vivo, Arthur Hamel-Senecal, Federico Torre, Alexandre Rudel, Luigi Manfre, Nicolas Amoretti
Summary: The study evaluated the clinical and radiological outcomes of patients with lumbar spinal stenosis treated with a removable percutaneous interspinous process spacer device, demonstrating significant pain reduction, functional improvement, and increased neural foramina area at 3-month follow-up with favorable safety profile.
Article
Clinical Neurology
Steven M. Falowski, Louis J. Raso, Vipul Mangal, Ali Nairizi, Denis G. Patterson, Michael Danko, Rafael Justiz, Rainer S. Vogel, Sebastian Koga, Yousseff Josephson, Jason E. Pope, Oluwatodimu Richard Raji
Summary: The study investigates the efficacy of minimally invasive treatments for low back pain in the early period after treatment and their importance for long-term success. The results show significant clinical improvement in pain for most patients at 6 months post-op, with minimal procedure-related adverse events.
JOURNAL OF PAIN RESEARCH
(2023)
Review
Medicine, Research & Experimental
Alan D. Kaye, Amber N. Edinoff, Shavonne N. Temple, Aaron J. Kaye, Azem A. Chami, Rutvij J. Shah, Bruce M. Dixon, Michael A. Alvarado, Elyse M. Cornett, Omar Viswanath, Ivan Urits, Aaron K. Calodney
Summary: Spinal stenosis is the narrowing of the spinal canal, causing compression of nerve roots. Treatment options include implants and surgical interventions, with newer procedures showing promise in safety and efficacy.
ADVANCES IN THERAPY
(2021)
Article
Medicine, Research & Experimental
Peter G. Whang, Oth Tran, Howard L. Rosner
Summary: This study compared the postoperative outcomes and rates of subsequent interventions between lumbar spinal stenosis (LSS) patients treated with an interspinous spacer device (ISD) and those with open decompression or fusion. The results showed that compared to ISD patients, those who received open surgery were more likely to require subsequent fusion or other lumbar spine surgeries, and were also more likely to experience short-term life-threatening events and long-term complications. Additionally, ISD patients had lower costs.
ADVANCES IN THERAPY
(2023)
Article
Clinical Neurology
Steven M. Falowski, Louis J. Raso, Vip Mangal, Ali Narizi, Denis G. Patterson, Michael D. Danko, Rafael Justiz, Rainer S. Vogel, Sebastian Koga, Yousseff Josephson, Jason E. Pope
Summary: This study investigates the efficacy and safety of interspinous fixation as a treatment for lumbar degenerative disc disease. The results of the interim analysis suggest that this approach can provide pain relief and improve functionality.
Review
Clinical Neurology
Steven M. Falowski, Vipul Mangal, Jason Pope, Anish Patel, Mark Coleman, Dan Kendall, Richard Brouillette, Michael A. Fishman
Summary: This retrospective analysis evaluated the use of ISF for patients with lumbar degenerative disc disease and spinal stenosis. The results showed a 0% adverse event rate, significant pain reduction, and successful outcomes, indicating the safety and efficacy of ISF performed by interventional pain physicians.
JOURNAL OF PAIN RESEARCH
(2021)
Article
Anesthesiology
Ahmed J. Awad, Braden Jex, Gwynne Kirchen, Stacy Peterson, Sarah A. Endrizzi, Peter A. Pahapill
Summary: The study demonstrates the favorable long-term efficacy of SCS in treating neurogenic claudication, especially for patients without prior surgical decompression. Despite its retrospective nature and single-center design, the results suggest that SCS can be considered as part of conservative treatment to help patients alleviate spine-related pain.
Article
Surgery
T. J. Florence, Irene Say, Kunal S. Patel, Ansley Unterberger, Azim Laiwalla, Andrew C. Vivas, Daniel C. Lu
Summary: IPD placement carries procedural risk and requires careful pre-operative evaluation. Neurosurgical consultation and supervision are recommended for higher-risk IPD cases.
FRONTIERS IN SURGERY
(2022)
Review
Pharmacology & Pharmacy
Y-X Hu, Y-F Wang, J. Han, S-M Liu, H. Wang
Summary: With the advancement of minimally invasive techniques, percutaneously placed interspinous stabilization devices have been gradually recognized by doctors and patients as the future direction in this field. This paper reviews the current clinical research progress in this area and emphasizes the importance of conducting more clinical studies with long-term follow-up.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2022)
Article
Oncology
Ryosuke Fujinaka, Shohei Komatsu, Kazuki Terashima, Yusuke Demizu, Satoshi Omiya, Masahiro Kido, Hirochika Toyama, Sunao Tokumaru, Tomoaki Okimoto, Takumi Fukumoto
Summary: Spacer placement surgery using an ePTFE spacer for abdominopelvic malignant tumors is technically feasible and acceptable for subsequent PT. However, severe spacer-related late complications were observed in some patients, highlighting the importance of careful long-term follow-up and prompt therapeutic intervention.
RADIATION ONCOLOGY
(2023)
Article
Engineering, Chemical
Jiazhou He, Tsai-Hsuan Chen, Kui Yang, Liang Luo, Chia-Hung Hou, Jinxing Ma
Summary: Brackish water desalination is an important opportunity to meet the increasing global demand for clean water. Capacitive deionization (CDI) is an attractive electrochemical separation technology for treating water salinity, and the innovative stop-flow (SF) discharge operation has shown high efficiency in minimizing brine volume. This study compared the desalination performance of CDI with single-pass and SF discharge operation modes, revealing the trade-off between water recovery and CDI performance deterioration caused by higher feed concentrations. The study also provides valuable insights into the scaling mechanism during SF discharge operation, which is crucial for CDI material design and operating protocol optimization in brackish water desalination.
Article
Engineering, Biomedical
Hangkai Shen, Guy R. Fogel, Jia Zhu, Zhenhua Liao, Weiqiang Liu
Summary: LFPI reduced motion and intradiscal pressure at the transition segment under static loading, but induced higher motion and pressure at the adjacent segment. After surgery, vibration amplitudes of the L3-4 intradiscal pressure and L4-5 facet joint force decreased significantly. The DIAM system showed the most comparable biomechanics to the intact model and reduced dynamic responses under WBV.
INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING
(2021)
Article
Multidisciplinary Sciences
Minhyeok Heo, Jihwan Yun, Hanjong Kim, Sang-Soo Lee, Seonghun Park
Summary: This study aimed to optimize a lumbar interspinous fixation device (LIFD) using a finite element model, allowing for minimally invasive surgery without compromising the normal behavior of the lumbar spine. The optimum number of spring turns and spring wire diameter were determined based on the dynamic range of motion (ROM) perspective. The optimized device was found to enhance stability and reduce the risk of degenerative diseases in adjacent lumbar segments.
Article
Engineering, Biomedical
Gaiping Zhao, Xiaoyu Wang, Tielong Liu, Lianfeng Dong
Summary: This study introduces a lumbar customized posterior fixation system that provides better mobility restriction and lower stress at the surgical level, with a more pronounced reduction in stress on the intervertebral discs.
MEDICAL ENGINEERING & PHYSICS
(2022)
Review
Integrative & Complementary Medicine
Ya-nan Sun, Yi An, Yan-Ji Zhou, Xi-You Wang, Chang-He Yu
Summary: The study aimed to evaluate the effectiveness of Non-Pharmaceutical Chinese Medical (NPCM) therapy for the treatment of Degenerative Lumbar Spinal Stenosis (DLSS). A comprehensive search of randomized controlled trials was conducted, and the results showed that acupuncture was superior to sham acupuncture in alleviating back pain and improving lumbar function. However, insufficient evidence was available to assess the efficacy of other NPCM therapies.
COMPLEMENTARY THERAPIES IN MEDICINE
(2023)