A Synaptic Function Approach to Investigating Complex Psychiatric Diseases

Derepression of a Neuronal Inhibitor due to miRNA Dysregulation in a Schizophrenia-Related Microdeletion

(2013) Bin Xu et al.   CELL

Imaging Patients with Psychosis and a Mouse Model Establishes a Spreading Pattern of Hippocampal Dysfunction and Implicates Glutamate as a Driver

(2013) Scott A. Schobel et al.   NEURON

Age-Dependent MicroRNA Control of Synaptic Plasticity in 22q11 Deletion Syndrome and Schizophrenia

(2012) L. R. Earls et al.   JOURNAL OF NEUROSCIENCE

Loss of microRNAs in pyramidal neurons leads to specific changes in inhibitory synaptic transmission in the prefrontal cortex

(2012) Ruby Hsu et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Cognitive, Behavioural and Psychiatric Phenotype in 22q11.2 Deletion Syndrome

(2011) Nicole Philip et al.   BEHAVIOR GENETICS

Mice lacking Ran binding protein 1 are viable and show male infertility

(2011) Masahiro Nagai et al.   FEBS LETTERS

Evidence for altered hippocampal function in a mouse model of the human 22q11.2 microdeletion

(2011) Liam J. Drew et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Genetic inactivation of GSK3α rescues spine deficits in Disc1-L100P mutant mice

(2011) Frankie H.F. Lee et al.   SCHIZOPHRENIA RESEARCH

A Thalamo-Hippocampal-Ventral Tegmental Area Loop May Produce the Positive Feedback that Underlies the Psychotic Break in Schizophrenia

(2010) John E. Lisman et al.   BIOLOGICAL PSYCHIATRY

Serine racemase deletion disrupts memory for order and alters cortical dendritic morphology

(2010) L. M. DeVito et al.   GENES BRAIN AND BEHAVIOR

Dysregulation of Presynaptic Calcium and Synaptic Plasticity in a Mouse Model of 22q11 Deletion Syndrome

(2010) L. R. Earls et al.   JOURNAL OF NEUROSCIENCE

Impaired hippocampal–prefrontal synchrony in a genetic mouse model of schizophrenia

(2010) Torfi Sigurdsson et al.   NATURE

Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

(2010) Akiko Hayashi-Takagi et al.   NATURE NEUROSCIENCE

Refining the 22q11.2 deletion breakpoints in DiGeorge syndrome by aCGH

(2009) D.C. Bittel et al.   CYTOGENETIC AND GENOME RESEARCH

Connectivity Patterns Revealed by Mapping of Active Inputs on Dendrites of Thalamorecipient Neurons in the Auditory Cortex

(2009) R. J. Richardson et al.   JOURNAL OF NEUROSCIENCE

Psychiatric Disorders and Intellectual Functioning Throughout Development in Velocardiofacial (22q11.2 Deletion) Syndrome

(2009) Tamar Green et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Spine Modifications Associated with Long-Term Potentiation

(2009) Yunlei Yang et al.   NEUROSCIENTIST

Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system

(2009) C. S. Barros et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model

(2008) Kimberly L Stark et al.   NATURE GENETICS

Palmitoylation-dependent neurodevelopmental deficits in a mouse model of 22q11 microdeletion

(2008) Jun Mukai et al.   NATURE NEUROSCIENCE

Silent synapses and the emergence of a postsynaptic mechanism for LTP

(2008) Geoffrey A. Kerchner et al.   NATURE REVIEWS NEUROSCIENCE

Dissecting the Components of Long-Term Potentiation

(2008) Jay A. Blundon et al.   NEUROSCIENTIST

A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition

(2008) M. Kvajo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA