MAGUKs, Synaptic Development, and Synaptic Plasticity

The backbone of the post-synaptic density originated in a unicellular ancestor of choanoflagellates and metazoans

(2010) Alexandre Alié et al.   BMC EVOLUTIONARY BIOLOGY

Evolution of the MAGUK protein gene family in premetazoan lineages

(2010) Alex de Mendoza et al.   BMC EVOLUTIONARY BIOLOGY

Autophosphorylated CaMKIIα Acts as a Scaffold to Recruit Proteasomes to Dendritic Spines

(2010) Baris Bingol et al.   CELL

Beta-2 adrenergic receptor mediated ERK activation is regulated by interaction with MAGI-3

(2010) Xiaomei Yang et al.   FEBS LETTERS

TheDrosophilaLarval Neuromuscular Junction as a Model for Scaffold Complexes at Glutamatergic Synapses: Benefits and Limitations

(2010) Ulrich Thomas et al.   JOURNAL OF NEUROGENETICS

In Vivo Composition of NMDA Receptor Signaling Complexes Differs between Membrane Subdomains and Is Modulated by PSD-95 And PSD-93

(2010) I. Delint-Ramirez et al.   JOURNAL OF NEUROSCIENCE

Selected SALM (Synaptic Adhesion-Like Molecule) Family Proteins Regulate Synapse Formation

(2010) W. Mah et al.   JOURNAL OF NEUROSCIENCE

Synaptic Localization and Function of Sidekick Recognition Molecules Require MAGI Scaffolding Proteins

(2010) M. Yamagata et al.   JOURNAL OF NEUROSCIENCE

Postsynaptic Clustering and Activation of Pyk2 by PSD-95

(2010) J. A. Bartos et al.   JOURNAL OF NEUROSCIENCE

Autonomous CaMKII Can Promote either Long-Term Potentiation or Long-Term Depression, Depending on the State of T305/T306 Phosphorylation

(2010) H. J. Pi et al.   JOURNAL OF NEUROSCIENCE

SAP102 Is a Highly Mobile MAGUK in Spines

(2010) C. Y. Zheng et al.   JOURNAL OF NEUROSCIENCE

LRRTMs and Neuroligins Bind Neurexins with a Differential Code to Cooperate in Glutamate Synapse Development

(2010) T. J. Siddiqui et al.   JOURNAL OF NEUROSCIENCE

The Postsynaptic Adenomatous Polyposis Coli (APC) Multiprotein Complex Is Required for Localizing Neuroligin and Neurexin to Neuronal Nicotinic Synapses in Vivo

(2010) M. M. Rosenberg et al.   JOURNAL OF NEUROSCIENCE

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

CaMKII Triggers the Diffusional Trapping of Surface AMPARs through Phosphorylation of Stargazin

(2010) Patricio Opazo et al.   NEURON

Single-Molecule Discrimination of Discrete Perisynaptic and Distributed Sites of Actin Filament Assembly within Dendritic Spines

(2010) Nicholas A. Frost et al.   NEURON

TARP Phosphorylation Regulates Synaptic AMPA Receptors through Lipid Bilayers

(2010) Akio Sumioka et al.   NEURON

Organization of NMDA receptors at extrasynaptic locations

(2010) R.S. Petralia et al.   NEUROSCIENCE

The role of SAP97 in synaptic glutamate receptor dynamics

(2010) MacKenzie A. Howard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcium/calmodulin-dependent serine protein kinase and mental retardation

(2009) Yi-Ping Hsueh   ANNALS OF NEUROLOGY

Assembly of a β2-adrenergic receptor—GluR1 signalling complex for localized cAMP signalling

(2009) Mei-ling A Joiner et al.   EMBO JOURNAL

Ca2+/Calmodulin-dependent Protein Kinase II Binds to and Phosphorylates a Specific SAP97 Splice Variant to Disrupt Association with AKAP79/150 and Modulate α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid-type Glutamate Receptor (AMPAR) Activity

(2009) Yelyzaveta A. Nikandrova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PSD-95 Uncouples Dopamine-Glutamate Interaction in the D1/PSD-95/NMDA Receptor Complex

(2009) J. Zhang et al.   JOURNAL OF NEUROSCIENCE

Synaptic SAP97 Isoforms Regulate AMPA Receptor Dynamics and Access to Presynaptic Glutamate

(2009) C. L. Waites et al.   JOURNAL OF NEUROSCIENCE

A critical role for PSD-95/AKAP interactions in endocytosis of synaptic AMPA receptors

(2009) Samarjit Bhattacharyya et al.   NATURE NEUROSCIENCE

SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathway

(2009) Okunola Jeyifous et al.   NATURE NEUROSCIENCE

The origin and evolution of synapses

(2009) Tomás J. Ryan et al.   NATURE REVIEWS NEUROSCIENCE

Organization and dynamics of PDZ-domain-related supramodules in the postsynaptic density

(2009) Wei Feng et al.   NATURE REVIEWS NEUROSCIENCE

LRRTM2 Interacts with Neurexin1 and Regulates Excitatory Synapse Formation

(2009) Joris de Wit et al.   NEURON

LRRTM2 Functions as a Neurexin Ligand in Promoting Excitatory Synapse Formation

(2009) Jaewon Ko et al.   NEURON

CASK Functions as a Mg2+-Independent Neurexin Kinase

(2008) Konark Mukherjee et al.   CELL

PSD-95 promotes synaptogenesis and multiinnervated spine formation through nitric oxide signaling

(2008) Irina Nikonenko et al.   JOURNAL OF CELL BIOLOGY

Developmental roles for Homer: more than just a pretty scaffold

(2008) Lisa Foa et al.   JOURNAL OF NEUROCHEMISTRY

Cdk5 Regulates the Phosphorylation of Tyrosine 1472 NR2B and the Surface Expression of NMDA Receptors

(2008) S. Zhang et al.   JOURNAL OF NEUROSCIENCE

SynGAP Regulates Steady-State and Activity-Dependent Phosphorylation of Cofilin

(2008) H. J. Carlisle et al.   JOURNAL OF NEUROSCIENCE

Synaptic adhesion-like molecules (SALMs) promote neurite outgrowth

(2008) Philip Y. Wang et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Quiet as a mouse: dissecting the molecular and genetic basis of hearing

(2008) Steve D. M. Brown et al.   NATURE REVIEWS GENETICS

Destabilization of the Postsynaptic Density by PSD-95 Serine 73 Phosphorylation Inhibits Spine Growth and Synaptic Plasticity

(2008) Pascal Steiner et al.   NEURON

Post-synaptic density-93 mediates tyrosine-phosphorylation of the N-methyl-d-aspartate receptors

(2008) Y. Sato et al.   NEUROSCIENCE

Differential trafficking of AMPA and NMDA receptors by SAP102 and PSD-95 underlies synapse development

(2008) G. M. Elias et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural plasticity with preserved topology in the postsynaptic protein network

(2008) T. A. Blanpied et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

α-Isoform of calcium-calmodulin-dependent protein kinase II and postsynaptic density protein 95 differentially regulate synaptic expression of NR2A– and NR2B–containing N-methyl-d-aspartate receptors in hippocampus

(2007) C.S. Park et al.   NEUROSCIENCE