Article
Neurosciences
Logan T. Dowdle, Geoffrey Ghose, Kamil Ugurbil, Essa Yacoub, Luca Vizioli
Summary: By utilizing faces as a visual category, specific task manipulations, and ultra-high field fMRI, the study revealed the crucial role of the right inferior-temporal lobe in top-down modulations under challenging conditions, uniquely encoding trial-by-trial variability in face perception.
Article
Biology
Helen Blank, Arjen Alink, Christian Buechel
Summary: Perception is an active inference that combines prior expectations with sensory input. This study aimed to understand how the strength of prior expectations is represented in the human brain. The results showed that expectation strength is represented in higher-level face-sensitive regions, supporting hierarchical theories of predictive processing. These findings suggest that higher-level sensory regions represent weighted priors and that face expectations are represented in higher-level face-identity areas.
COMMUNICATIONS BIOLOGY
(2023)
Article
Behavioral Sciences
Maho Hashiguchi, Takahiko Koike, Tomoyo Morita, Tokiko Harada, Denis Le Bihan, Norihiro Sadato
Summary: The perception and cognitive interpretation of time duration is subjective and connected with arousal and interoceptive signals. This study found that the insula, a critical brain region for integrating information from the external world with the organism's inner state, plays a central role in the perception of time duration and contributes to its estimation accuracy. The results also showed that the right anterior insular cortex and inferior frontal gyrus are involved in the accurate perception of temporal duration.
Article
Psychology, Mathematical
Joost de Jong, Elkan G. Akyurek, Hedderik van Rijn
Summary: The estimation of time is influenced by global and local statistical context, with short durations being overestimated compared to the global distribution, and durations following long durations also being overestimated. Two models, the internal reference model and the Bayesian account of time estimation, were compared and tested, with results supporting the Bayesian perspective on time estimation.
PSYCHONOMIC BULLETIN & REVIEW
(2021)
Article
Mathematics
Yanhong Wei, Huili Tang
Summary: This paper investigates the effective utilization of video conferencing in an online learning environment. It presents a case study based on the principles of educational neuroscience and distance education to promote the usage of digital technologies in higher education.
JOURNAL OF MATHEMATICS
(2022)
Article
Neurosciences
Benjamin L. Deck, Apoorva Kelkar, Brian Erickson, Fareshte Erani, Eric Mcconathey, Daniela Sacchetti, Olufunsho Faseyitan, Roy Hamilton, John D. Medaglia
Summary: This study found that individual's cognitive control behaviors can be predicted by inter-network connectivity, and the LDMN plays a specific role in switching and inhibiting behaviors.
Article
Environmental Sciences
Pranietha Mudliar, Laura O'Brien
Summary: Polycentric governance is important in addressing complex environmental challenges through multiple decision centers, but interactions between these centers can lead to conflicts and power struggles. In Lake Victoria’s fisheries, overlaps between higher and lower-level authorities drive out lower-level involvement in management, despite challenges like resource scarcities and bureaucracy hindering information-sharing. Cooperative overlaps between higher-level authorities increase oversight over lower-level authorities, impacting policy development and implementation.
ENVIRONMENTAL SCIENCE & POLICY
(2021)
Article
Psychology
Martin Riemer, Paula Vieweg, Hedderik van Rijn, Thomas Wolbers
Summary: This study investigates the impact of chronometric counting on a two-interval duration discrimination task. The results show that modifying the task leads to a decrease in judgment precision, a shift of the point of subjective equality, and an increase in reaction times. Additionally, participants are less likely to engage in spontaneous counting in the modified task version.
ATTENTION PERCEPTION & PSYCHOPHYSICS
(2022)
Article
Neurosciences
Harrison Ritz, Conor J. Wild, Ingrid S. Johnsrude
Summary: This study used functional magnetic resonance imaging to assess the processing of spoken sentences under distraction, and found that more cognitive effort is required when dealing with degraded speech. Moreover, the study showed that attention-related regions are affected when speech quality declines during processing of clear speech.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Green & Sustainable Science & Technology
Trinh Manh Hung, Hieu K. T. Ngo, Ly M. T. Luong, Hong H. T. C. Le, Dung Phung, Pham Minh Chinh, Son Nghiem, Nguyen T. Hue, Phong K. Thai
Summary: This study investigates the association between higher fuel prices and PM2.5 concentrations in Vietnam. The results show that an increase in diesel prices can significantly decrease PM2.5 levels in Ho Chi Minh City and Hanoi, while there is no significant association between gasoline prices and PM2.5. These findings provide valuable insights for formulating environmental policies regarding different fuel excises.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Multidisciplinary Sciences
Silvia Polver, Gabor P. Haden, Hermann Bulf, Istvan Winkler, Brigitta Toth
Summary: The ability to process sound duration is crucial in early age for auditory perception functions. This study reconstructs the sources of ERP waveforms sensitive to sound duration in infants using anatomical templates and confirms developmental changes between 4 and 9 months in auditory and language-related areas. The results demonstrate the feasibility of using anatomical templates in developmental populations.
SCIENTIFIC REPORTS
(2023)
Editorial Material
Biology
Polytimi Frangou, William T. Clarke
Summary: By combining methods that monitor blood oxygenation and biochemicals, researchers have discovered how the brain processes both perceived and unperceived stimuli.
Article
Environmental Sciences
Hang Liu, Liqin Su, Xi Chen, Sisi Wang, Yibin Cheng, Shaobin Lin, Liang Ding, Jingyi Liu, Chen Chen, Frederick W. Unverzagt, Ann M. Hake, Yinlong Jin, Sujuan Gao
Summary: This study found that higher cadmium exposure is associated with greater cognitive decline in older Chinese adults, as evidenced by lower scores in various cognitive tests and significant association with cognitive decline over a 3-year period.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Psychology, Multidisciplinary
Xuejun Liu, Xianjun Sun, Qin Hao
Summary: This study explores the influence mechanism of discrimination perception on higher vocational students' career exploration. The results indicate that discrimination perception is significantly negatively correlated with core self-evaluation, psychological flexibility, and career exploration. It is found that core self-evaluation and psychological flexibility mediate the effect between discrimination perception and career exploration. Therefore, it is suggested to pay attention to the cultivation of core self-evaluation and psychological flexibility among higher vocational students, strengthen the teaching quality, and improve the image of vocational colleges.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Endocrinology & Metabolism
Zheng Chen, Lan-Ping Wu, Tuo-Chao Peng
Summary: This study investigated the association between prediabetes and serum neurofilament light chain (sNfL) levels in adolescents. The results showed that adolescents with prediabetes undergoing elective orthopedic surgery had higher sNfL levels.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Substance Abuse
Jonatan Ottino-Gonzalez, Hugh Garavan, Matthew D. Albaugh, Zhipeng Cao, Renata B. Cupertino, Nathan Schwab, Philip A. Spechler, Nicholas Allen, Eric Artiges, Tobias Banaschewski, Arun L. W. Bokde, Erin Burke Quinlan, Ruediger Bruehl, Catherine Orr, Janna Cousijn, Sylvane Desrivieres, Herta Flor, John J. Foxe, Juliane H. Froehner, Anna E. Goudriaan, Penny Gowland, Antoine Grigis, Andreas Heinz, Robert Hester, Kent Hutchison, Chiang-Shan R. Li, Edythe D. London, Valentina Lorenzetti, Maartje Luijten, Frauke Nees, Rocio Martin-Santos, Jean-Luc Martinot, Sabina Millenet, Reza Momenan, Marie-Laure Paillere Martinot, Dimitri Papadopoulos Orfanos, Martin P. Paulus, Luise Poustka, Lianne Schmaal, Gunter Schumann, Rajita Sinha, Michael N. Smolka, Nadia Solowij, Dan J. Stein, Elliot A. Stein, Anne Uhlmann, Ruth J. Holst, Dick J. Veltman, Henrik Walter, Robert Whelan, Reinout W. Wiers, Murat Yucel, Sheng Zhang, Neda Jahanshad, Paul M. Thompson, Patricia Conrod, Scott Mackey
Summary: Graph theoretic analysis of structural covariance networks provides insights into brain organization in alcohol dependence. This study found that a specific structural covariance network profile can serve as an early marker for alcohol dependence in adults, and may also be a pre-existing risk factor for problematic drinking.
Article
Psychology, Developmental
Di Chen, Tianye Jia, Wei Cheng, Miao Cao, Tobias Banaschewski, Gareth J. Barker, Arun L. W. Bokde, Uli Bromberg, Christian Buchel, Sylvane Desrivieres, Herta Flor, Antoine Grigis, Hugh Garavan, Penny A. Gowland, Andreas Heinz, Bernd Ittermann, Jean-Luc Martinot, Marie-Laure Paillere Martinot, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomas Paus, Luise Poustka, Juliane H. Frohner, Michael N. Smolka, Henrik Walter, Robert Whelan, T. W. Robbins, Barbara J. Sahakian, Gunter Schumann, Jianfeng Feng
Summary: Using neuroimaging data, this study identified reduced activations in the medial frontal cortex and the thalamus during reward anticipation as neural biomarkers for persistent attention-deficit/hyperactivity disorder (ADHD) symptoms.
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2022)
Article
Psychology, Developmental
Lisa J. Pijnenburg, Anais Kaplun, Lieuwe de Haan, Magdalena Janecka, Lauren Smith, Abraham Reichenberg, Tobias Banaschewski, Arun L. W. Bokde, Erin Burke Quinlan, Sylvane Desrivieres, Antoine Grigis, Hugh Garavan, Penny Gowland, Andreas Heinz, Bernd Ittermann, Jean-Luc Martinot, Marie-Laure Paillere Martinot, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomas Paus, Luise Poustka, Sarah Hohmann, Sabina Millenet, Juliane H. Froehner, Michael N. Smolka, Henrik Walter, Robert Whelan, Gunter Schumann, Eva Velthorst
Summary: This study suggests that autistic traits are associated with less frequent and lower quantity of alcohol use during adolescence. Adolescents with higher levels of autistic traits, including social impairment, detail orientation, and anxiety, were found to consume less alcohol and engage in less binge drinking.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Neurosciences
Yan Sun, Tianye Jia, Edward D. Barker, Di Chen, Zuo Zhang, Jiayuan Xu, Suhua Chang, Guangdong Zhou, Yun Liu, Nicole Tay, Qiang Luo, Xiao Chang, Tobias Banaschewski, Arun L. W. Bokde, Herta Flor, Antoine Grigis, Hugh Garavan, Andreas Heinz, Jean-Luc Martinot, Marie-Laure Paillere Martinot, Eric Artiges, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomas Paus, Luise Poustka, Sarah Hohmann, Sabina Millenet, Juliane H. Froehner, Michael N. Smolka, Henrik Walter, Robert Whelan, Lin Lu, Jie Shi, Gunter Schumann, Sylvane Desrivieres
Summary: Negative life events (NLEs) increase the risk for externalizing behaviors (EBs) and internalizing behaviors (IBs). DNA methylation associated with behavioral problems may reflect this risk and long-lasting effects of NLEs.
BIOLOGICAL PSYCHIATRY
(2023)
Article
Psychology, Developmental
Helene Vulser, Herve S. Lemaitre, Stella Guldner, Pauline Bezivin-Frere, Martin Loffler, Anna S. Sarvasmaa, Jessica Massicotte-Marquez, Eric Artiges, Marie-Laure Paillere Martinot, Irina Filippi, Ruben Miranda, Argyris Stringaris, Betteke Maria van Noort, Jani Penttila, Yvonne Grimmer, Andreas Becker, Tobias Banaschewski, Arun L. W. Bokde, Sylvane Desrivieres, Juliane H. Frohner, Hugh Garavan, Antoine Grigis, Penny A. Gowland, Andreas Heinz, Dimitri Papadopoulos Orfanos, Luise Poustka, Michael N. Smolka, Philip A. Spechler, Henrik Walter, Robert Whelan, Gunter Schumann, Herta Flor, Jean-Luc Martinot, Frauke Nees
Summary: Adolescence is a critical period for circadian rhythm, with a shift toward eveningness. Eveningness in adolescence predicts later onset of depressive symptoms. This study investigates the structural variations associated with chronotype in early adolescence and its contribution to the development of depressive symptoms.
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2023)
Article
Environmental Sciences
Oksana Senyk, Volodymyr Abramov, Viktoriia Bedan, Alina Bunas, Marharyta Hrechkosii, Olena Lutsenko, Tetiana Mandzyk, Marc Wittmann
Summary: This study assessed the time orientations of Ukrainian students living in different regions before and during the crises in 2014-2016. The findings revealed that residents in the region far from the war zone had an increased future time orientation, while residents in the regions close to the war zone had a decreased future time orientation. This suggests that time perspectives are influenced by specific social, economic, and political factors and evaluations, and can adapt to extreme life circumstances.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Biology
Damisela Linares Gutierrez, Stefan Schmidt, Karin Meissner, Marc Wittmann
Summary: This study is the first to demonstrate the relative decrease in self-awareness and time perception during meditation through the measurement of heart rate, breathing rate, and the performance of a metronome task. Compared to a control condition of reading, meditation exhibited a mixed pattern of increased and decreased bodily activity in terms of heart rate and breathing rate. Meditators subjectively perceived their body boundaries less strongly, paid less attention to time, and felt time pass more quickly during meditation. However, no significant differences were observed between conditions in the metronome task.
Article
Physics, Multidisciplinary
David Lopez Perez, Arun L. W. Bokde, Christian M. Kerskens
Summary: Aging affects brain structure and cognitive capabilities, but current magnetic resonance imaging (MRI) methods are unable to accurately reflect cognitive decline. However, MRI signals may contain information about brain activity beyond commonly used signals. A study using a zero-spin echo (ZSE) weighted MRI sequence found that signals evoked by heartbeats (HES) have properties similar to electrophysiology. Comparing different age groups, the complexity of HES was found to decrease with age, and stability and chaoticity were particularly sensitive to age. Complexity measures were related to cognitive performance, indicating the potential use of HES for understanding brain dynamics.
EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS
(2023)
Article
Biochemistry & Molecular Biology
Zhipeng Cao, Renata B. Cupertino, Jonatan Ottino-Gonzalez, Alistair Murphy, Devarshi Pancholi, Anthony Juliano, Bader Chaarani, Matthew Albaugh, Dekang Yuan, Nathan Schwab, James Stafford, Anna E. Goudriaan, Kent Hutchison, Chiang-Shan R. Li, Maartje Luijten, Martine Groefsema, Reza Momenan, Lianne Schmaal, Rajita Sinha, Ruth J. van Holst, Dick J. Veltman, Reinout W. Wiers, Bernice Porjesz, Tristram Lett, Tobias Banaschewski, Arun L. W. Bokde, Sylvane Desrivieres, Herta Flor, Antoine Grigis, Penny Gowland, Andreas Heinz, Rudiger Bruehl, Jean-Luc Martinot, Marie-Laure Paillere Martinot, Eric Artiges, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomas Paus, Luise Poustka, Sarah Hohmann, Sabina Millenet, Juliane H. Froehner, Lauren Robinson, Michael N. Smolka, Henrik Walter, Jeanne Winterer, Gunter Schumann, Robert Whelan, Ravi R. Bhatt, Alyssa Zhu, Patricia Conrod, Neda Jahanshad, Paul M. Thompson, Scott Mackey, Hugh Garavan
Summary: In this study, researchers identified a shared spatial pattern of cortical thickness (CT) in normative development and several psychiatric and neurological disorders. Further analysis revealed significant spatial correspondences between this pattern and widespread lower CT observed in psychiatric disorders, as well as the spatial pattern of normative maturation and aging. Transcriptional analysis also identified a set of genes closely related to this pattern, indicating disrupted neurodevelopment in the pathogenesis of psychiatric diseases emerging during adolescence.
MOLECULAR PSYCHIATRY
(2023)
Article
Biochemistry & Molecular Biology
Alice Chavanne, Marie Laure Paillere Martinot, Jani Penttilae, Yvonne Grimmer, Patricia Conrod, Argyris Stringaris, Betteke van Noort, Corinna Isensee, Andreas Becker, Tobias Banaschewski, Arun L. W. Bokde, Sylvane Desrivieres, Herta Flor, Antoine Grigis, Hugh Garavan, Penny Gowland, Andreas Heinz, Ruediger Bruehl, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomas Paus, Luise Poustka, Sarah S. Hohmann, Sabina Millenet, Juliane Froehner, Michael Smolka, Henrik Walter, Robert Whelan, Gunter Schumann, Jean-Luc Martinot, Eric Artiges
Summary: Recent studies have found MRI correlates of prospective anxiety symptoms in youth, but their predictive value is still uncertain. This study used machine-learning algorithms to predict clinical anxiety using MRI data and psychometric scores. The results showed that psychometric features were the main predictors for overall anxiety disorders, while MRI regional volumes were more valuable for predicting GAD. In conclusion, future clinical anxiety in non-anxious 14-year-old adolescents can be individually predicted using psychometric features, and including neuroanatomical data improves the prediction of GAD.
MOLECULAR PSYCHIATRY
(2023)
Article
Computer Science, Interdisciplinary Applications
Harshvardhan Gazula, Kelly Rootes-Murdy, Bharath Holla, Sunitha Basodi, Zuo Zhang, Eric Verner, Ross Kelly, Pratima Murthy, Amit Chakrabarti, Debasish Basu, Subodh Bhagyalakshmi Nanjayya, Rajkumar Lenin Singh, Roshan Lourembam Singh, Kartik Kalyanram, Kamakshi Kartik, Kumaran Kalyanaraman, Krishnaveni Ghattu, Rebecca Kuriyan, Sunita Simon Kurpad, Gareth J. Barker, Rose Dawn Bharath, Sylvane Desrivieres, Meera Purushottam, Dimitri Papadopoulos Orfanos, Eesha Sharma, Matthew Hickman, Mireille Toledano, Nilakshi Vaidya, Tobias Banaschewski, Arun L. W. Bokde, Herta Flor, Antoine Grigis, Hugh Garavan, Penny Gowland, Andreas Heinz, Rudiger Bruhl, Jean-Luc Martinot, Marie-Laure Paillere Martinot, Eric Artiges, Frauke Nees, Tomas Paus, Luise Poustka, Juliane H. Frohner, Lauren Robinson, Michael N. Smolka, Henrik Walter, Jeanne Winterer, Robert Whelan, Jessica A. Turner, Anand D. Sarwate, Sergey M. Plis, Vivek Benegal, Gunter Schumann, Vince D. Calhoun
Summary: With the growth of decentralized/federated analysis approaches in neuroimaging, the opportunities to study brain disorders using data from multiple sites has grown multi-fold. One such initiative is the Neuromark, a fully automated spatially constrained independent component analysis (ICA) that is used to link brain network abnormalities among different datasets, studies, and disorders while leveraging subject-specific networks.
Article
Multidisciplinary Sciences
Rui Miguel Costa, Pedro Campos, Madalena Wiborg, Catarina Rebolo, Marc Wittmann, Juergen Kornmeier
Summary: This study explored the prevalence, correlates, and emotional reactions to visual snow in the general Portuguese population through online surveys. The results showed that the frequency of visual snow correlated with tinnitus frequency and entoptic phenomena, and it was related to absorption. Although most people experienced minimal distress caused by visual snow, a substantial minority reported moderate to high levels of distress.
Article
Psychology, Developmental
Stella Guldner, Anna S. Sarvasmaa, Herve Lemaitre, Jessica Massicotte, Helene Vulser, Ruben Miranda, Pauline Bezivin-Frere, Irina Filippi, Jani Penttila, Tobias Banaschewski, Gareth J. Barker, Arun L. W. Bokde, Uli Bromberg, Christian Buechel, Patricia J. Conrod, Sylvane Desrivieres, Herta Flor, Vincent Frouin, Juergen Gallinat, Hugh Garavan, Penny Gowland, Andreas Heinz, Frauke Nees, Dimitri Papadopoulos-Orfanos, Michael N. Smolka, Gunter Schumann, Eric Artiges, Marie-Laure Paillere Martinot, Jean-Luc Martinot
Summary: Sleep is crucial for neural maturation and emotion regulation in adolescents, and can have long-term effects on white matter development and affective processing in at-risk individuals. This study examined the relationship between sleep patterns and internalizing problems in adolescents aged 14-19 years. The results showed that increased weekend sleep duration and variability in sleep duration between weekdays and weekends were associated with improved white matter development and decreased internalizing problems. These findings suggest that catch-up sleep on weekends may serve as a protective strategy against the negative effects of insufficient sleep.
DEVELOPMENTAL COGNITIVE NEUROSCIENCE
(2023)
Article
Clinical Neurology
Matthew D. Albaugh, James. J. Hudziak, Philip A. Spechler, Bader Chaarani, Claude Lepage, Seun Jeon, Pierre Rioux, Alan C. Evans, Tobias Banaschewski, Arun L. W. Bokde, Sylvane Desrivieres, Herta Flor, Penny Gowland, Andreas Heinz, Bernd Ittermann, Jean-Luc Martinot, Marie-Laure Paillere Martinot, Frauke Nees, Dimitri Papadopoulos Orfanos, Luise Poustka, Sabina Millenet, Juliane H. Froehner, Michael N. Smolka, Henrik Walter, Robert Whelan, Gunter Schumann, Alexandra S. Potter, Hugh Garavan
Summary: This study examines the association between conduct problems and cerebral cortical development in a large longitudinal sample of adolescents. The results show an interaction between conduct problem scores and age-related cortical thinning in several brain regions. Higher levels of conduct problems are associated with accelerated age-related thinning.
PSYCHIATRY RESEARCH-NEUROIMAGING
(2023)
Article
Psychology, Developmental
Jessica N. Stepanous, Luke Munford, Pamela Qualter, Frauke Nees, Rebecca Elliott, IMAGEN Consortium
Summary: The period of adolescence is characterized by the interplay between social context, brain development, and emotional symptoms. This study aimed to investigate the associations between peer problems, family support, socioeconomic stress, emotional symptoms, amygdala volume, and vmPFC GMV in both sexes. The findings revealed that peer problems and emotional symptoms changed together over time, and there was a positive correlation between vmPFC GMV, peer problems, and emotional symptoms in males. Additionally, greater family support was associated with slower growth of amygdala volume in males. These findings contribute to our understanding of the complex relationship between social, emotional, and brain development and offer potential avenues for promoting mental health.
JOURNAL OF YOUTH AND ADOLESCENCE
(2023)
Article
Neurosciences
Song Xue, Feng Kong, Yiying Song, Jia Liu
Summary: This study used resting-state functional magnetic resonance imaging to explore the relationship between individual's spontaneous neural activity and social interaction anxiety in a nonclinical population. The results showed that social interaction anxiety was correlated with the fractional amplitude of low-frequency fluctuations in several brain regions, and that emotional intelligence partially mediated this relationship. This study provides evidence for the neural basis of social interaction anxiety in the normal population and highlights the role of emotional intelligence in this anxiety.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Katsuyuki Yamaguchi, Takuya Yazawa
Summary: This study provides morphometric data on the development of the human medullary arcuate nucleus (AN) by examining the brains of preterm and perinatal infants. The results show that AN morphology demonstrates asymmetry and individual variability during the fetal period. The volume and neuronal number of AN increase exponentially with age, while neuronal density decreases exponentially. The AN may undergo neuron death and neuroblasts production after mid-gestation.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Zhan Zhou, Weixin Dai, Tianxiao Liu, Min Shi, Yi Wei, Lifei Chen, Yubo Xie
Summary: Studies have shown that propofol-induced neurotoxicity is caused by disruption of mitochondrial fission and fusion, leading to an energy supply imbalance for developing neurons. Healthy mitochondria released by astrocytes can migrate to compromised neurons to mitigate propofol-induced neurotoxicity, but the exact mechanisms involved still need further clarification.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
An Chen, Song Hao, Yongpeng Han, Yang Fang, Yibei Miao
Summary: This study explores the efficacy of two forms of BCI attention training games and finds that physical games may be more effective than video games. The research also offers valuable insights for future game design from a neuroscience perspective.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Lina Liu, Luran Liu, Yunting Lu, Tianyuan Zhang, Wenting Zhao
Summary: This study reveals that GDI1 serves as a potential diagnostic biomarker for AD and inhibition of GDI1 can attenuate Aβ-induced neurotoxicity. The findings offer new insights for the treatment of AD.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Zahra Gholami, Ava Soltani Hekmat, Ali Abbasi, Kazem Javanmardi
Summary: This study investigated the effects of alamandine on allodynia in a rat model and found the presence of MrgD receptors in the vlPAG and RVM regions. Microinjection of alamandine resulted in a significant increase in paw withdrawal threshold and could be blocked by an MrgD receptor antagonist. Upregulation of MrgD receptor expression following allodynia induction suggests a potential compensatory mechanism in response to pain.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Mingliang Xu, Lei Xia, Junjie Li, Yehong Du, Zhifang Dong
Summary: This study found that DHF effectively alleviates sevoflurane-induced cognitive impairment in developing mice by restoring the balance between tau O-GlcNAcylation and phosphorylation. Therefore, DHF has the potential to be a therapeutic agent for treating cognitive impairment associated with anesthetics, such as sevoflurane.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Tsubasa Mitsutake, Hisato Nakazono, Takanori Taniguchi, Hisayoshi Yoshizuka, Maiko Sakamoto
Summary: The posterior parietal cortex plays a crucial role in postural stability, and transcranial electrical stimulation of this region can modulate physical control responses. This study found that cathodal stimulation significantly decreased joint angular velocity in multiple directions, while there were no significant differences with transcranial random noise stimulation.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Xishuai Yang, Wei Zhang, Xueli Chang, Zuopeng Li, Runquan Du, Junhong Guo
Summary: This study aims to evaluate the efficacy of low-dose rituximab (RTX) in patients with muscle-specific kinase antibody positive myasthenia gravis (MuSK-MG). The results showed that low-dose RTX treatment led to significant improvements in clinical symptoms and quality of life for patients with MuSK-MG.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Jian Zhang, Shunyuan Guo, Rong Tao, Fan Wang, Yihong Xie, Huizi Wang, Lan Ding, Yuejian Shen, Xiaoli Zhou, Junli Feng, Qing Shen
Summary: This study established an Alzheimer's disease (AD) model of zebrafish induced by AlCl3 and found that marine-derived plasmalogens (Pls) could alleviate cognitive impairments of AD zebrafish by reversing athletic impairment and altering the expression levels of genes related to oxidative stress, ferroptosis, synaptic dysfunction, and apoptosis.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Lu Li, Jiaqi Ren, Qi Fang, Liqiang Yu, Jintao Wang
Summary: ICU-AW is a common and severe neuromuscular complication in critically ill patients. Electrophysiological examination is essential for accurate diagnosis and early prediction of the disease. This study aimed to establish and validate an ICU-AW predictive model in SIRS patients, providing a practical tool for early clinical prediction.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Ahmad Alipour, Roghayeh Mohammadi
Summary: The present study aimed to investigate the separate and combined effects of anodal transcranial direct current stimulation (tDCS) over the primary motor cortex (M1) and left dorsolateral prefrontal cortex (F3) regions on pain relief in patients with type-2 diabetes suffering from neuropathic pain (NP). The results showed that tDCS had the potential to induce pain relief in patients with type-2 diabetes suffering from NP. The mean perceived pain intensity in the posttest was lower in the M1 stimulation group than in the F3 stimulation group. However, more trials with larger sample sizes are necessary to define clinically relevant effects.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Eduardo J. Fusse, Franciele F. Scarante, Maria A. Vicente, Mariana M. Marrubia, Flavia Turcato, Davi S. Scomparin, Melissa A. Ribeiro, Maria J. Figueiredo, Tamires A. V. Brigante, Francisco S. Guimaraes, Alline C. Campos
Summary: Repeated exposure to psychosocial stress alters the endocannabinoid system and affects brain regions associated with emotional distress. Enhancing the effects of endocannabinoids through pharmacological inhibition induces an anti-stress behavioral effect, possibly mediated by the mTOR signaling pathway.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Giulia Agostoni, Luca Bischetti, Federica Repaci, Margherita Bechi, Marco Spangaro, Irene Ceccato, Elena Cavallini, Luca Fiorentino, Francesca Martini, Jacopo Sapienza, Mariachiara Buonocore, Michele Francesco D'Incalci, Federica Cocchi, Carmelo Guglielmino, Roberto Cavallaro, Marta Bosia, Valentina Bambini
Summary: This study found a general impairment in humor comprehension in individuals with schizophrenia, with mental jokes being more difficult for both patients and controls. Humor comprehension was closely associated with the patients' overall pragmatic and linguistic profile, while the association with Theory of Mind (ToM) was minimal. Another notable finding was the increased appreciation of humor in individuals with schizophrenia, who rated jokes as funnier than controls did, regardless of whether they were correctly or incorrectly completed. The funniness ratings were not predicted by any measure, suggesting a dimension of humor untied to cognition or psychopathology.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Xiuping Gong, Qi Li, Yang Liu
Summary: This study demonstrates that Sev targets CREBBP to inhibit ALG13 transcription, leading to hippocampal damage and cognitive impairment.
NEUROSCIENCE LETTERS
(2024)
