Article
Neurosciences
Shulin Tang, Jie Guo, Bing Li, Zhikai Song
Summary: Social distance has an impact on reward processing in intertemporal choice, influencing brain activity and the evaluation process of time discounting. Different brain regions are responsible for processing soon-but-small and later-but-larger rewards in intertemporal choice. The P3b component is key in time discounting, with immediate and delayed rewards being valued in distinct brain regions.
FRONTIERS IN HUMAN NEUROSCIENCE
(2021)
Article
Education & Educational Research
Vlasios Kasapakis, Elena Dzardanova, Spyros Vosinakis, Androniki Agelada
Summary: Non-Verbal Cues (NVCs) play a significant role in enhancing communication effectiveness between individuals, both in real and virtual worlds. The transfer of NVCs between these two realms has garnered attention from the industry and research community, leading to the development of advanced technological solutions that enable real-time transfer of high-fidelity NVCs to virtual characters/avatars. This has greatly improved communication effectiveness in Immersive Virtual Reality (IVR) applications and Social Virtual Reality (SVR) platforms. As a result, Virtual Reality Learning Environments (VRLEs) have been created to aid students in learning sign language and communicating through it in both virtual and real worlds. However, there are still technological limitations that hinder the quality of this learning and communication experience. This study presents the design, development, and evaluation of an SVR compatible system that addresses these limitations and facilitates sign language learning and communication in virtual worlds. The findings highlight the importance of further investigation to enhance communication effectiveness through sign language in virtual environments.
INTERACTIVE LEARNING ENVIRONMENTS
(2023)
Review
Computer Science, Artificial Intelligence
Swastik Saxena, Somnath Dey, Miten Shah, Sundesh Gupta
Summary: Detecting and recognizing traffic signs in an unconstrained environment is challenging for autonomous vehicles. This study proposes a modified deep learning model for traffic sign detection and achieves high accuracy on different datasets, outperforming existing methods.
EXPERT SYSTEMS WITH APPLICATIONS
(2024)
Article
Psychology, Multidisciplinary
Marike Johnsdorf, Joanna Kisker, Thomas Gruber, Benjamin Schoene
Summary: This study aimed to investigate the differences in memory formation between virtual reality (VR) and conventional laboratory environments. The results showed that memory formation in VR is more complex and rich, involving multisensory integration and higher cognitive processes.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Behavioral Sciences
Zoe Lazar-Kurz, Jasmine Aziz, Katelyn J. McKearney, Cindy Hamon-Hill, Arthur MacDonald, Aaron Newman, Gail Eskes
Summary: Aging is associated with declines in cognitive function, including learning and memory. The present study used prism adaptation (PA) to investigate visuo-motor learning and error processing in older adults. EEG results indicated that older adults had similar initial error processing as young adults, but displayed reduced attentional orienting and enhanced context updating during the prism exposure phase. These findings provide insights into age-related learning differences and suggest potential clinical applications.
Article
Computer Science, Cybernetics
Seung Jin Chung, So Yeon Kim, Ki Han Kim
Summary: This study investigated the impact of spatial environment on user experience in VR exhibitions, finding that virtuality-based environments induce more active movements while reality-based environments provide a more comfortable feeling and better communication.
INTERNATIONAL JOURNAL OF HUMAN-COMPUTER STUDIES
(2024)
Article
Computer Science, Information Systems
Osama Halabi, Tooba Salahuddin, Abdel Ghani Karkar, Guillaume Alinier
Summary: This paper presents a virtual reality simulator for ambulance patient compartments, which can be used by emergency medical services (EMS) staff for practical training. The simulator allows customization of the compartment configuration based on personal preference, and provides vehicle orientation or training functions. User studies have demonstrated the usability and effectiveness of the simulator.
MULTIMEDIA TOOLS AND APPLICATIONS
(2022)
Article
Ergonomics
Zheng Xu, Xin Zou, Taeho Oh, Hai L. Vu
Summary: The study investigates drivers' perceptions and reactions towards freeway merging using a new approach with a multilevel simulation platform incorporating VR technology. Results show that conflict probability correlates positively with traffic flow, and the presence of ramp metering affects conflict frequency at freeway merges. The study suggests that the proposed VR simulation platform is beneficial for improving freeway merging safety and enhancing driver skills.
JOURNAL OF SAFETY RESEARCH
(2021)
Article
Engineering, Electrical & Electronic
Maikol Funk Drechsler, Jakob Peintner, Fabio Reway, Georg Seifert, Andreas Riener, Werner Huber
Summary: Scenario-based proving ground testing has become the standard test environment for homologating driver assistance systems, but it only covers a limited number of scenarios. Pedestrian targets used in these tests cannot accurately represent human movement patterns. To bridge the gap between simulation and real-world testing, MiRE, a mixed reality environment, combines real and simulated test procedures to evaluate the feasibility of testing in mixed reality.
IEEE TRANSACTIONS ON VEHICULAR TECHNOLOGY
(2022)
Article
Computer Science, Information Systems
Chyanna Wee, Kian Meng Yap, Woan Ning Lim
Summary: In this study, a framework is developed to address the issues students face when learning programming, such as the abstract nature of programming and misconceptions of programming concepts. The framework consists of three modules powered by a simulation engine. The study found that using VR intervention significantly improves programming concept comprehension and is more engaging than traditional video lectures according to the participants' ratings.
Article
Computer Science, Artificial Intelligence
Camillo Porcaro, Fabrizio Vecchio, Francesca Miraglia, Giancarlo Zito, Paolo Maria Rossini
Summary: Alzheimer's disease is a common cause of dementia, characterized by progressive decline in cognitive abilities and social behavior. The use of P3b spatial filters as a marker can accurately predict the conversion from mild cognitive impairment to Alzheimer's disease status.
INTERNATIONAL JOURNAL OF NEURAL SYSTEMS
(2022)
Article
Computer Science, Software Engineering
David Mal, Erik Wolf, Nina Dollinger, Carolin Wienrich, Marc Erich Latoschik
Summary: This study extends the existing knowledge about the significance of the Proteus effect in serious virtual reality applications by considering the relationship between self-embodiment and the virtual environment. The results showed that the congruence between the avatar and environment significantly affected the avatar's plausibility, but not the sense of embodiment or spatial presence. The Proteus effect only emerged in participants who had a strong sense of virtual body ownership, highlighting its importance in facilitating the effect.
IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS
(2023)
Article
Computer Science, Software Engineering
David Mal, Erik Wolf, Nina Dollinger, Carolin Wienrich, Marc Erich Latoschik
Summary: This study extends the understanding of the Proteus effect for serious virtual reality applications by considering the congruence between self-embodiment and the virtual environment. Avatar and environment congruence significantly affected the avatar's plausibility, but not the sense of embodiment or spatial presence. However, the Proteus effect only emerged for participants with a high feeling of virtual body ownership, suggesting that a strong sense of having and owning a virtual body is key to facilitating the Proteus effect.
IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS
(2023)
Article
Computer Science, Hardware & Architecture
Yasar Dasdemir
Summary: The popularity of virtual reality experiences is increasing due to technological advances, accessibility, and user interest. However, locomotion in VR applications can have physical and psychological effects on users. Predicting potential problems is crucial for understanding and mitigating risks.
Article
Psychology, Biological
Chien-Heng Chu, Shih-Chun Kao, Charles H. Hillman, Feng-Tzu Chen, Ruei-Hong Li, Jing-Yi Ai, Yu-Kai Chang
Summary: This study aimed to assess the effects of varying intensity and duration on inhibitory control. The results showed that low-intensity, moderate-intensity, and high-intensity exercise were beneficial for inhibitory control. These exercise conditions resulted in improved behavioral performance and modulations of neural activity compared to a reading control condition.
Article
Neurosciences
Song Xue, Feng Kong, Yiying Song, Jia Liu
Summary: This study used resting-state functional magnetic resonance imaging to explore the relationship between individual's spontaneous neural activity and social interaction anxiety in a nonclinical population. The results showed that social interaction anxiety was correlated with the fractional amplitude of low-frequency fluctuations in several brain regions, and that emotional intelligence partially mediated this relationship. This study provides evidence for the neural basis of social interaction anxiety in the normal population and highlights the role of emotional intelligence in this anxiety.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Katsuyuki Yamaguchi, Takuya Yazawa
Summary: This study provides morphometric data on the development of the human medullary arcuate nucleus (AN) by examining the brains of preterm and perinatal infants. The results show that AN morphology demonstrates asymmetry and individual variability during the fetal period. The volume and neuronal number of AN increase exponentially with age, while neuronal density decreases exponentially. The AN may undergo neuron death and neuroblasts production after mid-gestation.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Zhan Zhou, Weixin Dai, Tianxiao Liu, Min Shi, Yi Wei, Lifei Chen, Yubo Xie
Summary: Studies have shown that propofol-induced neurotoxicity is caused by disruption of mitochondrial fission and fusion, leading to an energy supply imbalance for developing neurons. Healthy mitochondria released by astrocytes can migrate to compromised neurons to mitigate propofol-induced neurotoxicity, but the exact mechanisms involved still need further clarification.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
An Chen, Song Hao, Yongpeng Han, Yang Fang, Yibei Miao
Summary: This study explores the efficacy of two forms of BCI attention training games and finds that physical games may be more effective than video games. The research also offers valuable insights for future game design from a neuroscience perspective.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Lina Liu, Luran Liu, Yunting Lu, Tianyuan Zhang, Wenting Zhao
Summary: This study reveals that GDI1 serves as a potential diagnostic biomarker for AD and inhibition of GDI1 can attenuate Aβ-induced neurotoxicity. The findings offer new insights for the treatment of AD.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Zahra Gholami, Ava Soltani Hekmat, Ali Abbasi, Kazem Javanmardi
Summary: This study investigated the effects of alamandine on allodynia in a rat model and found the presence of MrgD receptors in the vlPAG and RVM regions. Microinjection of alamandine resulted in a significant increase in paw withdrawal threshold and could be blocked by an MrgD receptor antagonist. Upregulation of MrgD receptor expression following allodynia induction suggests a potential compensatory mechanism in response to pain.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Mingliang Xu, Lei Xia, Junjie Li, Yehong Du, Zhifang Dong
Summary: This study found that DHF effectively alleviates sevoflurane-induced cognitive impairment in developing mice by restoring the balance between tau O-GlcNAcylation and phosphorylation. Therefore, DHF has the potential to be a therapeutic agent for treating cognitive impairment associated with anesthetics, such as sevoflurane.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Tsubasa Mitsutake, Hisato Nakazono, Takanori Taniguchi, Hisayoshi Yoshizuka, Maiko Sakamoto
Summary: The posterior parietal cortex plays a crucial role in postural stability, and transcranial electrical stimulation of this region can modulate physical control responses. This study found that cathodal stimulation significantly decreased joint angular velocity in multiple directions, while there were no significant differences with transcranial random noise stimulation.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Xishuai Yang, Wei Zhang, Xueli Chang, Zuopeng Li, Runquan Du, Junhong Guo
Summary: This study aims to evaluate the efficacy of low-dose rituximab (RTX) in patients with muscle-specific kinase antibody positive myasthenia gravis (MuSK-MG). The results showed that low-dose RTX treatment led to significant improvements in clinical symptoms and quality of life for patients with MuSK-MG.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Jian Zhang, Shunyuan Guo, Rong Tao, Fan Wang, Yihong Xie, Huizi Wang, Lan Ding, Yuejian Shen, Xiaoli Zhou, Junli Feng, Qing Shen
Summary: This study established an Alzheimer's disease (AD) model of zebrafish induced by AlCl3 and found that marine-derived plasmalogens (Pls) could alleviate cognitive impairments of AD zebrafish by reversing athletic impairment and altering the expression levels of genes related to oxidative stress, ferroptosis, synaptic dysfunction, and apoptosis.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Lu Li, Jiaqi Ren, Qi Fang, Liqiang Yu, Jintao Wang
Summary: ICU-AW is a common and severe neuromuscular complication in critically ill patients. Electrophysiological examination is essential for accurate diagnosis and early prediction of the disease. This study aimed to establish and validate an ICU-AW predictive model in SIRS patients, providing a practical tool for early clinical prediction.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Ahmad Alipour, Roghayeh Mohammadi
Summary: The present study aimed to investigate the separate and combined effects of anodal transcranial direct current stimulation (tDCS) over the primary motor cortex (M1) and left dorsolateral prefrontal cortex (F3) regions on pain relief in patients with type-2 diabetes suffering from neuropathic pain (NP). The results showed that tDCS had the potential to induce pain relief in patients with type-2 diabetes suffering from NP. The mean perceived pain intensity in the posttest was lower in the M1 stimulation group than in the F3 stimulation group. However, more trials with larger sample sizes are necessary to define clinically relevant effects.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Eduardo J. Fusse, Franciele F. Scarante, Maria A. Vicente, Mariana M. Marrubia, Flavia Turcato, Davi S. Scomparin, Melissa A. Ribeiro, Maria J. Figueiredo, Tamires A. V. Brigante, Francisco S. Guimaraes, Alline C. Campos
Summary: Repeated exposure to psychosocial stress alters the endocannabinoid system and affects brain regions associated with emotional distress. Enhancing the effects of endocannabinoids through pharmacological inhibition induces an anti-stress behavioral effect, possibly mediated by the mTOR signaling pathway.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Giulia Agostoni, Luca Bischetti, Federica Repaci, Margherita Bechi, Marco Spangaro, Irene Ceccato, Elena Cavallini, Luca Fiorentino, Francesca Martini, Jacopo Sapienza, Mariachiara Buonocore, Michele Francesco D'Incalci, Federica Cocchi, Carmelo Guglielmino, Roberto Cavallaro, Marta Bosia, Valentina Bambini
Summary: This study found a general impairment in humor comprehension in individuals with schizophrenia, with mental jokes being more difficult for both patients and controls. Humor comprehension was closely associated with the patients' overall pragmatic and linguistic profile, while the association with Theory of Mind (ToM) was minimal. Another notable finding was the increased appreciation of humor in individuals with schizophrenia, who rated jokes as funnier than controls did, regardless of whether they were correctly or incorrectly completed. The funniness ratings were not predicted by any measure, suggesting a dimension of humor untied to cognition or psychopathology.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Xiuping Gong, Qi Li, Yang Liu
Summary: This study demonstrates that Sev targets CREBBP to inhibit ALG13 transcription, leading to hippocampal damage and cognitive impairment.
NEUROSCIENCE LETTERS
(2024)