Article
Construction & Building Technology
Zhengrong Li, Han Zhu, Bing Dong, Xiaofeng Xu
Summary: A customized shading behavior identification model was developed to learn and identify the personalized shading behavior habits and indoor environmental preferences of targeted occupants, which can be embedded into the optimization controls of buildings. The model, based on subliminal perception, improved capturing personalized shading behavior by 12.56% using Random Forest algorithm with monitored data from an office.
ENERGY AND BUILDINGS
(2021)
Article
Biology
Henning Tiedemann, Yaniv Morgenstern, Filipp Schmidt, Roland W. Fleming
Summary: Humans have the ability to learn new visual concepts from just one example and can synthesize new variations based on this example. This suggests that humans rely on internal generative models to generalize from a single instance.
Article
Neurosciences
Juhyeon Lee, Minyoung Jung, Niv Lustig, Jong-Hwan Lee
Summary: We studied neural representations for visual perception of handwritten digits and visual objects using fMRI and a CNN. The CNN model's neural representation showed a hierarchical topography mapping similar to the human visual system. Lower convolutional layers of the CNN had greater similarity with early visual areas, while higher convolutional layers were encoded in higher-order visual areas. The neural representations for human visual perception were more widely distributed across the whole brain compared to the CNN model.
HUMAN BRAIN MAPPING
(2023)
Article
Multidisciplinary Sciences
Naoto Sato, Mana Miyamoto, Risa Santa, Ayaka Sasaki, Kenichi Shibuya
Summary: In this study, we investigated the cross-modal effect between odors and colors, both under recognizable and unrecognizable conditions. By using different concentrations of flavors from strawberries and tomatoes, we compared whether similar cross-modal effects can be obtained. The results showed that each odor, except for the subliminal tomato condition, was significantly associated with at least one color. This study suggests that the flavor of tomatoes produced a cross-modal effect in recognizable conditions, while the flavor of strawberries produced a cross-modal effect even in unrecognizable conditions.
Article
Linguistics
Hayden J. Peel, Kayla A. Royals, Philippe A. Chouinard
Summary: The study confirms the existence of subliminal word priming and finds that word priming is case insensitive. Despite the insensitivity to case, there is a general facilitation effect when words are presented in the same case.
JOURNAL OF PSYCHOLINGUISTIC RESEARCH
(2022)
Article
Multidisciplinary Sciences
Ying Wang, Xue Zhang, Chunhui Wang, Weifen Huang, Qian Xu, Dong Liu, Wen Zhou, Shanguang Chen, Yi Jiang
Summary: Using spaceflight and ground-based analog, this study reveals how the Earth's gravity helps maintain the human brain's sensitivity to biological motion signals. Prolonged microgravity or head-down tilt bed rest can reduce the inversion effect in perceiving biological motion, and the functional connectivity between cortical regions is strengthened.
NATURE COMMUNICATIONS
(2022)
Article
Computer Science, Artificial Intelligence
Md Jahidul Islam, Jiawei Mo, Junaed Sattar
Summary: The paper proposes a method to determine the 3D relative pose of pairs of communicating robots using human pose-based key-points, utilizing a 'leader-follower' framework and an iterative optimization algorithm for key-point refinement across viewpoints. The performance of the proposed system is evaluated through experiments in terrestrial and underwater environments, highlighting the essential role of refinement processes for accurate key-point correspondences.
Review
Multidisciplinary Sciences
S. Morfu, B. Usama, P. Marquie
Summary: This paper provides an overview of nonlinear resonance applications in image processing, introducing a threshold detector based on resonance properties for investigating the perception of subthreshold noisy images. It also compares the performance of stochastic resonance (SR) and vibrational resonance detectors, showing that the latter significantly outperforms the former in terms of image perception.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
(2021)
Article
Psychology, Multidisciplinary
Rongjun Zher-Wen, Rongjun Yu
Summary: Integrative processing is believed to rely on consciousness, but recent challenges have emerged regarding the existence of subliminal integration. This review critically evaluates evidence for 10 types of widely studied subliminal integration, including arithmetic processing, object-context integration, multi-word processing, etc., and also considers methodological issues related to awareness measures. The conclusion suggests that while reliable evidence for subliminal integration is lacking, this does not invalidate the concept of 'unconscious' integration defined through non-subliminal approaches.
BRITISH JOURNAL OF PSYCHOLOGY
(2023)
Article
Endocrinology & Metabolism
Emily E. Perszyk, Xue S. Davis, Jelena Djordjevic, Marilyn Jones-Gotman, Jessica Trinh, Zach Hutelin, Maria G. Veldhuizen, Leonie Koban, Tor D. Wager, Hedy Kober, Dana M. Small
Summary: This study found that the ability to imagine odours is associated with food cravings and weight gain. Through an observational study on 45 adults, it was discovered that the ability to imagine odours is correlated with the intensity of food cravings, which in turn promotes adiposity and leads to weight gain over time.
Article
Endocrinology & Metabolism
Emily E. Perszyk, Xue S. Davis, Jelena Djordjevic, Marilyn Jones-Gotman, Jessica Trinh, Zach Hutelin, Maria G. Veldhuizen, Leonie Koban, Tor D. Wager, Hedy Kober, Dana M. Small
Summary: Olfactory imagery drives food-cue reactivity (FCR) and increases weight.
Article
Food Science & Technology
Lu-lu Zhang, Chao Ma, Hou-yin Wang, Ying-ming Zheng, Qing-bin Zhang, Kui Zhong, Bo-lin Shi, Lei Zhao
Summary: The research focuses on the individual sensitivity, personality traits, and dietary habits that contribute to the perception of oral tingling sensation, which is important for developing tingling products. The survey indicates the correlation between individual ratings and sensitivity indicators. Additionally, the study reveals the significance of the power exponent of tingling and burning sensation. The findings provide insights for selecting sensory panelists and formulation design of tingling dishes and foods.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Multidisciplinary Sciences
Jie Cai, Xiaoning Sun, Jingyu Zhang, Xianghong Sun
Summary: The activation of subliminal stimuli is crucial in trust research. This study examined the impact of subliminal stimuli on team trust and the moderating effect of openness. The results demonstrated a significant influence of subliminal stimuli on team trust and the important role of openness. This study revealed the mechanism behind the effect of subliminal stimuli on team trust, providing empirical foundation for personalized interventions to improve team trust.
Article
Biochemistry & Molecular Biology
Tina J. Drechsel, Claudio Zippenfennig, Daniel Schmidt, Thomas L. Milani
Summary: This study investigated the effect of subliminal electrical noise (SEN) on vibration sensitivity in individuals with diabetes. The results showed no significant improvement in vibration perception thresholds (VPT) for diabetic individuals exposed to SEN. However, in the most severely affected individuals, SEN seemed to have a positive influence on vibratory perception.
Article
Neurosciences
Esther J. Putman, Raquel C. Galvan-Garza, Torin K. Clark
Summary: Research suggests that Galvanic vestibular stimulation (GVS) can significantly improve the learning of functional mobility tasks, with learning effects being retained even after GVS application is stopped. However, similar learning improvements were not observed in manual control tasks. High-level GVS appears to have some inhibitory effects on the learning ability of both tasks, but the effects are not significant.
FRONTIERS IN HUMAN NEUROSCIENCE
(2021)
Article
Multidisciplinary Sciences
Katsuhiko Sato, Hayato Hikita, Yuta Myojin, Kenji Fukumoto, Kazuhiro Murai, Sadatsugu Sakane, Takeshi Tamura, Takuo Yamai, Yasutoshi Nozaki, Teppei Yoshioka, Takahiro Kodama, Minoru Shigekawa, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
Article
Multidisciplinary Sciences
Yuto Shiode, Hayato Hikita, Satoshi Tanaka, Kumiko Shirai, Akira Doi, Sadatsugu Sakane, Yugo Kai, Tasuku Nakabori, Ryoko Yamada, Takahiro Kodama, Ryohei Narumi, Ryotaro Sakamori, Hidetoshi Eguchi, Takeshi Tomonaga, Tomohide Tatsumi, Tetsuo Takehara
SCIENTIFIC REPORTS
(2020)
Article
Gastroenterology & Hepatology
Yuta Myojin, Hayato Hikita, Masaya Sugiyama, Yoichi Sasaki, Kenji Fukumoto, Sadatsugu Sakane, Yuki Makino, Nobuyuki Takemura, Ryoko Yamada, Minoru Shigekawa, Takahiro Kodama, Ryotaro Sakamori, Shogo Kobayashi, Tomohide Tatsumi, Hiroshi Suemizu, Hidetoshi Eguchi, Norihiro Kokudo, Masashi Mizokami, Tetsuo Takehara
Summary: The study suggests that in the HCC microenvironment, the increase of HSCs producing GDF15 in an autophagy-dependent manner may be involved in tumor progression, while GDF15 deficiency can reduce the size of liver tumors caused by the steatohepatitis-based tumorigenesis model.
Article
Multidisciplinary Sciences
Yasutoshi Nozaki, Hayato Hikita, Satoshi Tanaka, Kenji Fukumoto, Makiko Urabe, Katsuhiko Sato, Yuta Myojin, Akira Doi, Kazuhiro Murai, Sadatsugu Sakane, Yoshinobu Saito, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
Summary: This study found that enhanced tumor formation from DEN-transformed hepatocytes by persistent hepatocyte apoptosis is mediated by increased oxidative stress, independent of compensatory liver regeneration. Controlling oxidative stress may play a critical role in suppressing hepatocarcinogenesis for patients with livers harboring transformed cells.
SCIENTIFIC REPORTS
(2021)
Article
Gastroenterology & Hepatology
Naoki Mizutani, Hayato Hikita, Yoshinobu Saito, Yuta Myojin, Katsuhiko Sato, Makiko Urabe, Tomohide Kurahashi, Yuto Shiode, Sadatsugu Sakane, Kazuhiro Murai, Yasutoshi Nozaki, Takahiro Kodama, Ryotaro Sakamori, Yuichi Yoshida, Tomohide Tatsumi, Tetsuo Takehara
Summary: Gab1 plays a crucial role in suppressing hepatocyte apoptosis in chronic liver diseases, leading to suppression of hepatocyte proliferation, liver fibrosis, and liver carcinogenesis, rather than in liver regeneration after acute liver injury.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
(2021)
Article
Gastroenterology & Hepatology
Kazuhiro Kozumi, Takahiro Kodama, Hiroki Murai, Sadatsugu Sakane, Olivier Govaere, Simon Cockell, Daisuke Motooka, Naruyasu Kakita, Yukinori Yamada, Yasuteru Kondo, Yuki Tahata, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Yoshihiro Kamada, Ann K. Daly, Quentin M. Anstee, Tomohide Tatsumi, Eiichi Morii, Tetsuo Takehara
Summary: The study conducted global RNA sequencing of liver tissue from 98 NAFLD patients, identifying THBS2 as a potential biomarker for NASH and advanced fibrosis. Serum TSP-2 levels were independent predictors of NASH and advanced fibrosis, stratifying patients based on the risk of hepatic complications.
Article
Gastroenterology & Hepatology
Sadatsugu Sakane, Hayato Hikita, Kumiko Shirai, Yuta Myojin, Youichi Sasaki, Shinnosuke Kudo, Kenji Fukumoto, Naoki Mizutani, Yuki Tahata, Yuki Makino, Ryoko Yamada, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
Summary: The study showed that autophagy was enhanced in white adipose tissues of mice fed a high-fat diet, and inhibition of autophagy in adipose tissues can ameliorate the liver pathology of NAFLD through adipose-liver crosstalk.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Gastroenterology & Hepatology
Yuta Myojin, Hayato Hikita, Yuki Tahata, Akira Doi, Seiya Kato, Yoichi Sasaki, Kumiko Shirai, Sadatsugu Sakane, Ryoko Yamada, Takahiro Kodama, Hideki Hagiwara, Yasuharu Imai, Naoki Hiramatsu, Shinji Tamura, Keiji Yamamoto, Kazuyoshi Ohkawa, Taizo Hijioka, Hiroyuki Fukui, Yoshinori Doi, Yukinori Yamada, Takayuki Yakushijin, Eiji Mita, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
Summary: This study evaluated the prognostic value of GDF15 for HCC occurrence after HCV elimination and found that GDF15, AFP, and the FIB-4 index can independently predict HCC risk, with a scoring system stratifying patients into different risk groups.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Review
Medicine, General & Internal
Ji Hyun Sung, Ryotaro Sakamori, Ryoko Yamada, Teppei Yoshioka, Sadatsugu Sakane, Yuki Tahata, Minoru Shigekawa, Takahiro Kodama, Hayato Hikita, Tomohide Tatsumi, Tetsuo Takehara
Summary: We present a case of a 34-year-old woman born with tetralogy of Fallot who underwent 5 cardiac repair procedures. She developed liver nodules and congestive cirrhosis due to severe mitral regurgitation and an atrial septal defect. A percutaneous liver biopsy revealed hepatocellular carcinoma with liver fibrosis, which was successfully treated with transarterial chemoembolization.
Letter
Gastroenterology & Hepatology
Yuta Myojin, Hayato Hikita, Yuki Tahata, Akira Doi, Seiya Kato, Yoichi Sasaki, Kumiko Shirai, Sadatsugu Sakane, Ryoko Yamada, Takahiro Kodama, Hideki Hagiwara, Yasuharu Imai, Naoki Hiramatsu, Shinji Tamura, Keiji Yamamoto, Kazuyoshi Ohkawa, Taizo Hijioka, Hiroyuki Fukui, Yoshinori Doi, Yukinori Yamada, Takayuki Yakushijin, Eiji Mita, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Article
Oncology
Yuki Makino, Hayato Hikita, Kenji Fukumoto, Ji Hyun Sung, Yoshihiro Sakano, Kazuhiro Murai, Sadatsugu Sakane, Takahiro Kodama, Ryotaro Sakamori, Jumpei Kondo, Shogo Kobayashi, Tomohide Tatsumi, Tetsuo Takehara
Summary: This study reveals that activation of p53 in hepatocytes promotes liver carcinogenesis derived from HPCs, elucidating a paradoxical aspect of the tumor suppressor gene p53 and a novel mechanism of liver carcinogenesis.
Article
Multidisciplinary Sciences
Kumiko Shirai, Hayato Hikita, Ryotaro Sakamori, Akira Doi, Yuki Tahata, Sadatsugu Sakane, Yoshihiro Kamada, Kazuhiro Murai, Akira Nishio, Ryoko Yamada, Takahiro Kodama, Yasutoshi Nozaki, Naruyasu Kakita, Hisashi Ishida, Fumihiko Nakanishi, Naoki Morishita, Kazuho Imanaka, Mitsuru Sakakibara, Tomohide Tatsumi, Eiji Miyoshi, Tetsuo Takehara
Summary: High serum Fuc-Hp levels at EOT were identified as an independent risk factor for HCC occurrence after SVR. When combined with BMI and albumin levels, Fuc-Hp can be used to stratify the risk of HCC development in patients with advanced fibrosis.
Review
Gastroenterology & Hepatology
Hyun Young Kim, Sadatsugu Sakane, Alvaro Eguileor, Raquel Carvalho Gontijo Weber, Wonseok Lee, Xiao Liu, Kevin Lam, Kei Ishizuka, Sara Brin Rosenthal, Karin Diggle, David A. Brenner, Tatiana Kisseleva
Summary: Liver fibrosis is a serious global health problem with no effective therapy currently available. Studies have shown that liver fibrosis is reversible and regression can occur when the underlying cause is removed. This review discusses the research progress in understanding the molecular mechanisms underlying the development and reversibility of liver fibrosis.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
(2024)
Article
Biochemical Research Methods
Xiao Liu, Kevin Lam, Huayi Zhao, Sadatsugu Sakane, Hyun Young Kim, Alvaro Eguileor, Karin Diggle, Shuai Wu, Raquel Carvalho Gontijo Weber, Pejman Soroosh, Mojgan Hosseini, Kristin Mekeel, David A. Brenner, Tatiana Kisseleva
Summary: Here, the authors present a protocol for isolating human hepatocytes and neural progenitor cells from normal and nonalcoholic steatohepatitis livers. They describe steps for perfusion and optimization of chemical digestion for maximal yield and cell viability. They also discuss the potential applications of liver cell cryopreservation in experimental and translational research.
Article
Gastroenterology & Hepatology
Makiko Urabe, Hayato Hikita, Yoshinobu Saito, Shinnosuke Kudo, Kenji Fukumoto, Naoki Mizutani, Yuta Myojin, Akira Doi, Katsuhiko Sato, Sadatsugu Sakane, Yuki Makino, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
Summary: The study reveals that the p53 gene plays a role in the impaired regenerative ability of the irradiated liver. Liver regeneration post-irradiation is suppressed, but this inhibition is alleviated by knocking out the p53 gene.
HEPATOLOGY COMMUNICATIONS
(2022)
Article
Neurosciences
Song Xue, Feng Kong, Yiying Song, Jia Liu
Summary: This study used resting-state functional magnetic resonance imaging to explore the relationship between individual's spontaneous neural activity and social interaction anxiety in a nonclinical population. The results showed that social interaction anxiety was correlated with the fractional amplitude of low-frequency fluctuations in several brain regions, and that emotional intelligence partially mediated this relationship. This study provides evidence for the neural basis of social interaction anxiety in the normal population and highlights the role of emotional intelligence in this anxiety.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Katsuyuki Yamaguchi, Takuya Yazawa
Summary: This study provides morphometric data on the development of the human medullary arcuate nucleus (AN) by examining the brains of preterm and perinatal infants. The results show that AN morphology demonstrates asymmetry and individual variability during the fetal period. The volume and neuronal number of AN increase exponentially with age, while neuronal density decreases exponentially. The AN may undergo neuron death and neuroblasts production after mid-gestation.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Zhan Zhou, Weixin Dai, Tianxiao Liu, Min Shi, Yi Wei, Lifei Chen, Yubo Xie
Summary: Studies have shown that propofol-induced neurotoxicity is caused by disruption of mitochondrial fission and fusion, leading to an energy supply imbalance for developing neurons. Healthy mitochondria released by astrocytes can migrate to compromised neurons to mitigate propofol-induced neurotoxicity, but the exact mechanisms involved still need further clarification.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
An Chen, Song Hao, Yongpeng Han, Yang Fang, Yibei Miao
Summary: This study explores the efficacy of two forms of BCI attention training games and finds that physical games may be more effective than video games. The research also offers valuable insights for future game design from a neuroscience perspective.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Lina Liu, Luran Liu, Yunting Lu, Tianyuan Zhang, Wenting Zhao
Summary: This study reveals that GDI1 serves as a potential diagnostic biomarker for AD and inhibition of GDI1 can attenuate Aβ-induced neurotoxicity. The findings offer new insights for the treatment of AD.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Zahra Gholami, Ava Soltani Hekmat, Ali Abbasi, Kazem Javanmardi
Summary: This study investigated the effects of alamandine on allodynia in a rat model and found the presence of MrgD receptors in the vlPAG and RVM regions. Microinjection of alamandine resulted in a significant increase in paw withdrawal threshold and could be blocked by an MrgD receptor antagonist. Upregulation of MrgD receptor expression following allodynia induction suggests a potential compensatory mechanism in response to pain.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Mingliang Xu, Lei Xia, Junjie Li, Yehong Du, Zhifang Dong
Summary: This study found that DHF effectively alleviates sevoflurane-induced cognitive impairment in developing mice by restoring the balance between tau O-GlcNAcylation and phosphorylation. Therefore, DHF has the potential to be a therapeutic agent for treating cognitive impairment associated with anesthetics, such as sevoflurane.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Tsubasa Mitsutake, Hisato Nakazono, Takanori Taniguchi, Hisayoshi Yoshizuka, Maiko Sakamoto
Summary: The posterior parietal cortex plays a crucial role in postural stability, and transcranial electrical stimulation of this region can modulate physical control responses. This study found that cathodal stimulation significantly decreased joint angular velocity in multiple directions, while there were no significant differences with transcranial random noise stimulation.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Xishuai Yang, Wei Zhang, Xueli Chang, Zuopeng Li, Runquan Du, Junhong Guo
Summary: This study aims to evaluate the efficacy of low-dose rituximab (RTX) in patients with muscle-specific kinase antibody positive myasthenia gravis (MuSK-MG). The results showed that low-dose RTX treatment led to significant improvements in clinical symptoms and quality of life for patients with MuSK-MG.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Jian Zhang, Shunyuan Guo, Rong Tao, Fan Wang, Yihong Xie, Huizi Wang, Lan Ding, Yuejian Shen, Xiaoli Zhou, Junli Feng, Qing Shen
Summary: This study established an Alzheimer's disease (AD) model of zebrafish induced by AlCl3 and found that marine-derived plasmalogens (Pls) could alleviate cognitive impairments of AD zebrafish by reversing athletic impairment and altering the expression levels of genes related to oxidative stress, ferroptosis, synaptic dysfunction, and apoptosis.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Lu Li, Jiaqi Ren, Qi Fang, Liqiang Yu, Jintao Wang
Summary: ICU-AW is a common and severe neuromuscular complication in critically ill patients. Electrophysiological examination is essential for accurate diagnosis and early prediction of the disease. This study aimed to establish and validate an ICU-AW predictive model in SIRS patients, providing a practical tool for early clinical prediction.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Ahmad Alipour, Roghayeh Mohammadi
Summary: The present study aimed to investigate the separate and combined effects of anodal transcranial direct current stimulation (tDCS) over the primary motor cortex (M1) and left dorsolateral prefrontal cortex (F3) regions on pain relief in patients with type-2 diabetes suffering from neuropathic pain (NP). The results showed that tDCS had the potential to induce pain relief in patients with type-2 diabetes suffering from NP. The mean perceived pain intensity in the posttest was lower in the M1 stimulation group than in the F3 stimulation group. However, more trials with larger sample sizes are necessary to define clinically relevant effects.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Eduardo J. Fusse, Franciele F. Scarante, Maria A. Vicente, Mariana M. Marrubia, Flavia Turcato, Davi S. Scomparin, Melissa A. Ribeiro, Maria J. Figueiredo, Tamires A. V. Brigante, Francisco S. Guimaraes, Alline C. Campos
Summary: Repeated exposure to psychosocial stress alters the endocannabinoid system and affects brain regions associated with emotional distress. Enhancing the effects of endocannabinoids through pharmacological inhibition induces an anti-stress behavioral effect, possibly mediated by the mTOR signaling pathway.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Giulia Agostoni, Luca Bischetti, Federica Repaci, Margherita Bechi, Marco Spangaro, Irene Ceccato, Elena Cavallini, Luca Fiorentino, Francesca Martini, Jacopo Sapienza, Mariachiara Buonocore, Michele Francesco D'Incalci, Federica Cocchi, Carmelo Guglielmino, Roberto Cavallaro, Marta Bosia, Valentina Bambini
Summary: This study found a general impairment in humor comprehension in individuals with schizophrenia, with mental jokes being more difficult for both patients and controls. Humor comprehension was closely associated with the patients' overall pragmatic and linguistic profile, while the association with Theory of Mind (ToM) was minimal. Another notable finding was the increased appreciation of humor in individuals with schizophrenia, who rated jokes as funnier than controls did, regardless of whether they were correctly or incorrectly completed. The funniness ratings were not predicted by any measure, suggesting a dimension of humor untied to cognition or psychopathology.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Xiuping Gong, Qi Li, Yang Liu
Summary: This study demonstrates that Sev targets CREBBP to inhibit ALG13 transcription, leading to hippocampal damage and cognitive impairment.
NEUROSCIENCE LETTERS
(2024)
