Article
Biochemistry & Molecular Biology
Shuang Zhai, Meng-Mei Yin, Huai-Qing Sun, Xue-Qin Jiang, Yun Liu, Charles Marshall, Ting Wu, Ming Xiao
Summary: This study aimed to determine the diurnal changes in cognitive and anxiety-like behaviors in mice following chronic sleep restriction (SR), and to investigate the relationship between these phenotypic differences and the diurnal variation of glymphatic clearance mediated by aquaporin4 (AQP4). The results showed that SR mice exhibited cognitive impairment and anxiety-like behaviors during the day, but not at night. Furthermore, AQP4 polarity and glymphatic transport ability were higher during the day, with lower levels of beta-amyloid and tau protein in the frontal cortex. These day-night differences were disrupted after SR, suggesting a potential circadian control of AQP4-mediated glymphatic clearance of toxic macromolecules from the brain.
Article
Biochemistry & Molecular Biology
Alpay Pelvan, Melike Bor, Seher Yolcu, Filiz Ozdemir, Ismail Turkan
Summary: This study investigated the impact of drought stress on GABA biosynthesis during the diurnal cycle in plants. The results suggest that oscillations in GABA biosynthesis during the day and night cycle have an effect on drought stress responses, which requires further elucidation through additional analysis.
PLANT SIGNALING & BEHAVIOR
(2021)
Article
Environmental Studies
Timo Savela
Summary: This article discusses the differences between landscapes and nightscapes, emphasizing how our encounters differ in daylight conditions compared to the dark. The author explores the definition and functioning of landscapes, highlighting how darkness negates them but can be restored through illumination. The article aims to illustrate the superiority of nightscapes in channeling desires and the opportunities they provide for personal expression and opposition using others' illumination.
LANDSCAPE RESEARCH
(2023)
Article
Neurosciences
Santosh Pothula, Rong-Jian Liu, Min Wu, Alexa-Nicole Sliby, Marina R. Picciotto, Pradeep Banerjee, Ronald S. Duman
Summary: The NMDAR PAM AGN-241751 exhibits antidepressant-like effects in mice, with GluN2B on excitatory neurons in the mPFC being identified as the key mediator of these behavioral effects.
NEUROPSYCHOPHARMACOLOGY
(2021)
Review
Clinical Neurology
Beatrice De Maria, Monica Parati, Laura Adelaide Dalla Vecchia, Maria Teresa La Rovere
Summary: This meta-analysis compares heart rate variability between healthy women and men, and explores the influence of sex- and gender-related factors. The results show that women have shorter mean RR intervals and lower variability in time domain indices compared to men. Sex-related differences were more evident in frequency domain indices during night-time.
CLINICAL AUTONOMIC RESEARCH
(2023)
Article
Neurosciences
Xin Li, Zhuo-Jun Du, Jun-Nan Xu, Zhi-Man Liang, Song Lin, Hao Chen, Shu-Ji Li, Xiao-Wen Li, Jian-Ming Yang, Tian-Ming Gao
Summary: Pharmacological manipulation of mGluR5 suggests its involvement in anxiety disorders, but the mechanism behind its role in stress-induced anxiety-like behavior is unclear. This study found that chronic restraint stress and mGluR5 knockdown lead to anxiety-like behavior and impaired inhibitory synaptic inputs in hippocampal CA1 pyramidal neurons. However, positive allosteric modulator of mGluR5 can rescue anxiety-like behavior and restore inhibitory synaptic inputs. These findings highlight the essential role of mGluR5 in mediating stress-induced anxiety-like behavior in hippocampal CA1 pyramidal neurons.
NEUROPSYCHOPHARMACOLOGY
(2023)
Article
Multidisciplinary Sciences
Aubrey Keirnan, Trevor H. Worthy, Jeroen B. Smaers, Karine Mardon, Andrew N. Iwaniuk, Vera Weisbecker
Summary: Nocturnal birds, including the letter-winged kite, show adaptations in their visual system for low-light conditions. The transition to nocturnality can occur rapidly without changes to hard-tissue indicators of vision. Skull measurements can provide insights into raptor behaviors beyond just nocturnality.
ROYAL SOCIETY OPEN SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Yue Qin, Yasong Du, Liqiang Chen, Yanyan Liu, Wenjing Xu, Ying Liu, Ying Li, Jing Leng, Yalan Wang, Xiao-Yong Zhang, Jianfeng Feng, Feng Zhang, Li Jin, Zilong Qiu, Xiaohong Gong, Hongyan Wang
Summary: This study identified an ASD-specific recurrent missense mutation in the SHANK1 gene, demonstrating strong pathogenic potential in vitro. Shank1 R882H-KI mice exhibited core symptoms of ASD and structural and cellular changes in key brain regions, indicating the causative role of SHANK1 in ASD and providing a reliable model for future studies.
MOLECULAR PSYCHIATRY
(2022)
Article
Social Work
Carolyn Barnes, Jamila Michener, Emily Rains
Summary: Research suggests that public assistance programs can be stigmatizing and cause stress for recipients, but fails to consider the differences between programs and policy design that result in varied bureaucratic encounters. Based on interviews with beneficiaries and staff members from the Supplemental Nutrition Assistance Program (SNAP), Special Supplemental Nutrition Program for Women, Infants, and Children (WIC), and Medicaid, this study examines how individuals perceive their experiences in different programs. The findings reveal that WIC staff members view the program as facilitative of positive personal interactions, while SNAP and Medicaid workers face pressure to process clients quickly and accurately, leading to frustration and suspicion. Furthermore, participants in all three programs describe positive interactions with WIC staff, but report stigmatizing encounters with SNAP and Medicaid staff.
SOCIAL SERVICE REVIEW
(2023)
Article
Engineering, Aerospace
Ruihua Zhang, Weihua Liu
Summary: This study establishes a theoretical simulation model and analyzes the factors affecting the oxygen concentration in the ullage space of the fuel tank, especially the temperature difference between day and night. The research results provide practical guidance for the design of the inert system and the calculation of the flammability exposure evaluation time.
AIRCRAFT ENGINEERING AND AEROSPACE TECHNOLOGY
(2023)
Article
Psychology, Biological
Melissa E. S. Richardson, Marie-Claire Boutrin, Synia Chunn, Michael Hall
Summary: Exposure to fragmented day-night cycles during development can have adverse effects on mice, leading to increased bodyweight gain, inability to avoid aberrant light exposure, and binge-like eating behaviors during adulthood.
PHYSIOLOGY & BEHAVIOR
(2022)
Article
Veterinary Sciences
Naief Dahran, Wael A. M. Ghonimi
Summary: This study aimed to identify and differentiate the different cell types filling the pineal gland parenchyma of mature male sheep. Pinealocytes and astrocytes were recognized as the two main cell types, with additional identification of neuron-like cells and pigmented-like cells.
OPEN VETERINARY JOURNAL
(2023)
Article
Zoology
Krystal A. Tolley
Summary: Arboreal chameleons can use a wide range of perches for both diurnal and nocturnal activities, with a preference for larger perches among larger individuals.
AFRICAN JOURNAL OF HERPETOLOGY
(2023)
Article
Philosophy
Lutz Niemann
Summary: This article examines the thoughts of Eugen Fink and Emmanuel Levinas through the metaphors of day and night. Their criticisms of the metaphysics of light and attempts to overcome it by contemplating the infinite are discussed. The article concludes with a comparison of their approaches.
Article
Philosophy
Damiano Migliorini
Summary: The article applies a Hegelian phenomenological method to examine the diachronic theoretical development of feminist philosophies, suggesting that they are inherently open to destabilization and dialectical sublation rather than having defined content or method. The analysis concludes with reflections on the future direction of feminist philosophies and the unique queer event that they represent.
Article
Neurosciences
Yang He, Jun Tang, Meng Zhang, Junjie Ying, Dezhi Mu
Summary: This study investigated the protective effects and mechanisms of human placenta derived mesenchymal stem cells (hPMSCs) transplantation in a rat model of hypoxic-ischemic encephalopathy (HIE). The results showed that hPMSCs transplantation reduced apoptosis and improved long-term neurological prognosis. Furthermore, the downregulation of Sema 3A/NRP-1 expression and activation of the PI3K/Akt/mTOR signaling pathway played a key role in the protective effects of hPMSCs.
Article
Neurosciences
Emily L. Isenstein, Edward G. Freedman, Jiayi Xu, Ian A. DeAndrea-Lazarus, John J. Foxe
Summary: This study evaluated electrophysiological discrimination of parametric somatosensory stimuli in healthy young adults to understand how the brain processes the duration of tactile information. The results showed that participants did not electrophysiologically discriminate between 100 and 115 ms, but they exhibited distinct electrophysiological responses when the deviant stimuli were 130, 145, and 160 ms. These findings contribute to a better understanding of tactile sensitivity in different clinical conditions.
Article
Neurosciences
Juliana R. Souza, Ludmila Lima-Silveira, Daniela Accorsi-Mendonca, Benedito H. Machado
Summary: This study demonstrates that A2A receptors play a crucial role in modulating synaptic transmission in the NTS neurons and are required for the enhancement of glutamatergic transmission observed under short-term sustained hypoxia conditions.
Article
Neurosciences
Miki Hashizume, Rina Ito, Rie Suge, Yasushi Hojo, Gen Murakami, Takayuki Murakoshi
Summary: The basolateral amygdaloid complex (BLA) is closely involved in the formation of emotional memories, including both aversive memory and contextual fear memory. Acute sleep deprivation (SD) disrupts the acquisition of tone-associated fear memory in juvenile rats, but has no significant effect on contextual fear memory. Slow network oscillation in the amygdala contributes to the formation of amygdala-dependent fear memory in relation to sleep.
Article
Neurosciences
Qunxian Wang, Shipeng Guo, Dongjie Hu, Xiangjun Dong, Zijun Meng, Yanshuang Jiang, Zijuan Feng, Weihui Zhou, Weihong Song
Summary: GSDME plays a crucial role in the pathogenesis of Alzheimer's disease by regulating the switch from apoptosis to pyroptosis and participating in neuroinflammatory response. Knockdown of GSDME has been shown to improve cognitive impairments, indicating that GSDME could be a therapeutic target for Alzheimer's disease.