Impaired Hippocampal Neuroligin-2 Function by Chronic Stress or Synthetic Peptide Treatment is Linked to Social Deficits and Increased Aggression

Animal models of social avoidance and social fear

(2013) Iulia Toth et al.   CELL AND TISSUE RESEARCH

Hippocampal Neuroligin-2 Overexpression Leads to Reduced Aggression and Inhibited Novelty Reactivity in Rats

(2013) Christine Kohl et al.   PLoS One

Neuroligin-1 induces neurite outgrowth through interaction with neurexin-1β and activation of fibroblast growth factor receptor-1

(2012) Michelle D. Gjørlund et al.   FASEB JOURNAL

Stress, anxiety, and dendritic spines: What are the connections?

(2012) B. Leuner et al.   NEUROSCIENCE

Hippocampus lesions induced deficits in social and spatial recognition in Octodon degus

(2011) Tomoko Uekita et al.   BEHAVIOURAL BRAIN RESEARCH

The ever-changing brain: Cellular and molecular mechanisms for the effects of stressful experiences

(2011) Bruce S. McEwen   Developmental Neurobiology

Chronic stress induces changes in the structure of interneurons and in the expression of molecules related to neuronal structural plasticity and inhibitory neurotransmission in the amygdala of adult mice

(2011) Javier Gilabert-Juan et al.   EXPERIMENTAL NEUROLOGY

Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia

(2011) Julie Gauthier et al.   HUMAN GENETICS

Identification and functional characterization of rare mutations of the neuroligin-2 gene ( NLGN2 ) associated with schizophrenia

(2011) Chicheng Sun et al.   HUMAN MOLECULAR GENETICS

Neocortical excitation/inhibition balance in information processing and social dysfunction

(2011) Ofer Yizhar et al.   NATURE

A Peptide Mimetic Targeting Trans-Homophilic NCAM Binding Sites Promotes Spatial Learning and Neural Plasticity in the Hippocampus

(2011) Igor Kraev et al.   PLoS One

Increased Dentate Gyrus Excitability in Neuroligin-2-Deficient Mice in Vivo

(2010) P. Jedlicka et al.   CEREBRAL CORTEX

Overexpression of the cell adhesion protein neuroligin-1 induces learning deficits and impairs synaptic plasticity by altering the ratio of excitation to inhibition in the hippocampus

(2010) Regina Dahlhaus et al.   HIPPOCAMPUS

Neuroligin-1 Deletion Results in Impaired Spatial Memory and Increased Repetitive Behavior

(2010) J. Blundell et al.   JOURNAL OF NEUROSCIENCE

Causal evidence for the involvement of the neural cell adhesion molecule, NCAM, in chronic stress-induced cognitive impairments

(2009) Reto Bisaz et al.   HIPPOCAMPUS

Common circuit defect of excitatory-inhibitory balance in mouse models of autism

(2009) Nadine Gogolla et al.   Journal of Neurodevelopmental Disorders

Chronic stress selectively reduces hippocampal volume in rats: a longitudinal magnetic resonance imaging study

(2009) Taekwan Lee et al.   NEUROREPORT

Chronic immobilization stress alters aspects of emotionality and associative learning in the rat.

(2008) Gwendolyn E. Wood et al.   BEHAVIORAL NEUROSCIENCE

Chronic mild stress generates clear depressive but ambiguous anxiety-like behaviour in rats

(2008) Hajnalka Kompagne et al.   BEHAVIOURAL BRAIN RESEARCH

Increased anxiety-like behavior in mice lacking the inhibitory synapse cell adhesion molecule neuroligin 2

(2008) J. Blundell et al.   GENES BRAIN AND BEHAVIOR

Synaptic Imbalance, Stereotypies, and Impaired Social Interactions in Mice with Altered Neuroligin 2 Expression

(2008) R. M. Hines et al.   JOURNAL OF NEUROSCIENCE

The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling

(2008) J M Bessa et al.   MOLECULAR PSYCHIATRY

Neuroligins and neurexins link synaptic function to cognitive disease

(2008) Thomas C. Südhof   NATURE

Crystal structure of the extracellular cholinesterase-like domain from neuroligin-2

(2008) J. Koehnke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism

(2008) S. Jamain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA