The Impact of MeCP2 Loss- or Gain-of-Function on Synaptic Plasticity

A Mouse Model for MeCP2 Duplication Syndrome: MeCP2 Overexpression Impairs Learning and Memory and Synaptic Transmission

(2012) E. S. Na et al.   JOURNAL OF NEUROSCIENCE

MeCP2: only 100% will do

(2012) Hsiao-Tuan Chao et al.   NATURE NEUROSCIENCE

The Role of MeCP2 in the Brain

(2011) Jacky Guy et al.   Annual Review of Cell and Developmental Biology

Novel clinical finding in MECP2 duplication syndrome

(2011) Magdalena Budisteanu et al.   EUROPEAN CHILD & ADOLESCENT PSYCHIATRY

MECP2 triplication in 3 brothers – A rarely described cause of familial neurological regression in boys

(2011) Shan S. Tang et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Experimental models of Rett syndrome based on Mecp2 dysfunction

(2011) Gaston Calfa et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Role of MeCP2, DNA methylation, and HDACs in regulating synapse function

(2011) Ege T. Kavalali et al.   Journal of Neurodevelopmental Disorders

Selective impact of MeCP2 and associated histone deacetylases on the dynamics of evoked excitatory neurotransmission

(2011) Erika D. Nelson et al.   JOURNAL OF NEUROPHYSIOLOGY

Loss of activity-induced phosphorylation of MeCP2 enhances synaptogenesis, LTP and spatial memory

(2011) Hongda Li et al.   NATURE NEUROSCIENCE

Synaptic plasticity deficits in an experimental model of rett syndrome: long-term potentiation saturation and its pharmacological reversal

(2011) S.-M. Weng et al.   NEUROSCIENCE

TheMECP2duplication syndrome

(2010) Melissa B. Ramocki et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Progressive cerebellar degenerative changes in the severe mental retardation syndrome caused by duplication of MECP2 and adjacent loci on Xq28

(2010) William Reardon et al.   EUROPEAN JOURNAL OF PEDIATRICS

The role of MeCP2 in CNS development and function

(2010) Elisa S. Na et al.   HORMONES AND BEHAVIOR

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

(2010) Hsiao-Tuan Chao et al.   NATURE

Autism and other neuropsychiatric symptoms are prevalent in individuals withMeCP2duplication syndrome

(2009) Melissa B. Ramocki et al.   ANNALS OF NEUROLOGY

MeCP2 functions largely cell-autonomously, but also non-cell-autonomously, in neuronal maturation and dendritic arborization of cortical pyramidal neurons

(2009) Noriyuki Kishi et al.   EXPERIMENTAL NEUROLOGY

Histone Deacetylases 1 and 2 Form a Developmental Switch That Controls Excitatory Synapse Maturation and Function

(2009) M. W. Akhtar et al.   JOURNAL OF NEUROSCIENCE

MeCP2-Mediated Transcription Repression in the Basolateral Amygdala May Underlie Heightened Anxiety in a Mouse Model of Rett Syndrome

(2009) M. Adachi et al.   JOURNAL OF NEUROSCIENCE

Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations

(2009) Christopher A. Chapleau et al.   NEUROBIOLOGY OF DISEASE

Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities

(2009) R. C. Samaco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function

(2009) J. Tao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

(2009) Daniela Tropea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolving role of MeCP2 in Rett syndrome and autism

(2009) Janine M LaSalle et al.   Epigenomics

Deletion of Mecp2 in Sim1-Expressing Neurons Reveals a Critical Role for MeCP2 in Feeding Behavior, Aggression, and the Response to Stress

(2008) Sharyl L. Fyffe et al.   NEURON

MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

(2008) M. Chahrour et al.   SCIENCE