Partial Agonists of the α3β4* Neuronal Nicotinic Acetylcholine Receptor Reduce Ethanol Consumption and Seeking in Rats

Neuronal Nicotinic Acetylcholine Receptors as Pharmacotherapeutic Targets for the Treatment of Alcohol Use Disorders

(2012) S. Chatterjee et al.   CNS & Neurological Disorders-Drug Targets

A novel series of [3.2.1] azabicyclic biaryl ethers as α3β4 and α6/4β4 nicotinic receptor agonists

(2010) John A. Lowe et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Pre-clinical properties of the α4β2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence

(2010) H Rollema et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activation of  4* nAChRs is Necessary and Sufficient for Varenicline-Induced Reduction of Alcohol Consumption

(2010) L. M. Hendrickson et al.   JOURNAL OF NEUROSCIENCE

Suppression of alcohol self-administration and reinstatement of alcohol seeking by melanin-concentrating hormone receptor 1 (MCH1-R) antagonism in Wistar rats

(2010) Andrea Cippitelli et al.   PSYCHOPHARMACOLOGY

Modulation of ethanol consumption by genetic and pharmacological manipulation of nicotinic acetylcholine receptors in mice

(2010) Helen M. Kamens et al.   PSYCHOPHARMACOLOGY

Variants in nicotinic acetylcholine receptors α5 and α3 increase risks to nicotine dependence

(2009) Xiangning Chen et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Preclinical pharmacology of the α4β2 nAChR partial agonist varenicline related to effects on reward, mood and cognition

(2009) Hans Rollema et al.   BIOCHEMICAL PHARMACOLOGY

Varenicline Reduces Alcohol Self-Administration in Heavy-Drinking Smokers

(2009) Sherry A. McKee et al.   BIOLOGICAL PSYCHIATRY

The CHRNA5-CHRNA3-CHRNB4 Nicotinic Receptor Subunit Gene Cluster Affects Risk for Nicotine Dependence in African-Americans and in European-Americans

(2009) N. L. Saccone et al.   CANCER RESEARCH

Biotransformation of an  4 2 Nicotinic Acetylcholine Receptor Partial Agonist in Sprague-Dawley Rats and the Dispositional Characterization of Its N-Carbamoyl Glucuronide Metabolite

(2009) C. L. Shaffer et al.   DRUG METABOLISM AND DISPOSITION

A Preliminary Benefit-Risk Assessment of Varenicline in Smoking Cessation

(2009) Kate Cahill et al.   DRUG SAFETY

A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5–CHRNA3–CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy

(2009) Rachel M. Freathy et al.   HUMAN MOLECULAR GENETICS

Intermittent Access to 20% Ethanol Induces High Ethanol Consumption in Long-Evans and Wistar Rats

(2008) Jeffrey A. Simms et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

The CHRNA5/A3/B4 Gene Cluster Variability as an Important Determinant of Early Alcohol and Tobacco Initiation in Young Adults

(2008) Isabel R. Schlaepfer et al.   BIOLOGICAL PSYCHIATRY

Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

(2008) J C Wang et al.   MOLECULAR PSYCHIATRY

Demonstration of functional α4-containing nicotinic receptors in the medial habenula

(2008) Carlos Fonck et al.   NEUROPHARMACOLOGY

Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans

(2008) G. Joslyn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA