Journal
NEUROPSYCHOLOGY REVIEW
Volume 19, Issue 3, Pages 312-323Publisher
SPRINGER
DOI: 10.1007/s11065-009-9107-0
Keywords
Episodic memory; Schizophrenia
Categories
Funding
- [5 P30 MH074543-03]
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Episodic memory impairments in individuals with schizophrenia have been well documented in the literature. However, despite the abundance of findings, constituent cognitive, neural, behavioral, and genetic components of the deficits continue to elude full characterization. This review provides a characterization of these deficits by organizing findings within three frameworks of interest: 1) neuroanatomical; 2) genetic; and 3) behavioral. Within each approach, evidence from imaging studies as well as behavioral studies is examined. The hope is that by synthesizing the cognitive science paradigms, molecular genetic neurophysiological findings, and computational algorithms applied to medial temporal lobe subregions, we will be able to expand our understanding of the types of compromises in episodic memory systems of individuals with schizophrenia.
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