Journal
NEUROPATHOLOGY
Volume 30, Issue 4, Pages 434-438Publisher
WILEY-BLACKWELL
DOI: 10.1111/j.1440-1789.2009.01073.x
Keywords
cerebral hemorrhage; CNS vasculitis; giant cell angiitis
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Giant cell angiitis of the CNS is an uncommon form of vasculitis. Neurological manifestations, both of the peripheral and CNS, are common. The most frequent manifestations are visual loss and stroke. Hemorrhagic onset is uncommon. Most cases have a fatal outcome and a tissue diagnosis is rarely established in life. We describe an unusual case of giant cell angiitis beginning as a hemorrhagic tumoral-like lesion. The results of the histological and ultrastructural analysis have also been reported. Our case illustrates that giant cell angiitis should be considered as a cause of intracerebral hemorrhage, particularly when associated with a relapsing and remitting disease of the CNS.
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