Journal
NEURON
Volume 69, Issue 5, Pages 835-837Publisher
CELL PRESS
DOI: 10.1016/j.neuron.2011.02.033
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Funding
- NIDA NIH HHS [R01 DA025967-03, R01 DA025967] Funding Source: Medline
- NINDS NIH HHS [R01 NS054770, R01 NS037585-14, R01 NS043142, R01 NS054770-06, R01 NS037585, R01 NS043142-11] Funding Source: Medline
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Though transmitters can be released from astrocytes, the conditions that permit their modulation of synaptic transmission are under debate. Santello et al. in this issue of Neuron now show that TNF alpha promotes a burst mode of glial transmitter release that escapes reuptake processes allowing access to neuronal NMDA receptors.
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