Article
Biology
Weizhen Xie, Marcus Cappiello, Michael A. Yassa, Edward Ester, Kareem A. Zaghloul, Weiwei Zhang, Floris P. de Lange
Summary: Classic models consider working memory and long-term memory as distinct mental faculties that are supported by different neural mechanisms. Recent evidence suggests that the medial temporal lobe may be involved in working memory, but the specific role of the entorhinal-DG/CA3 pathway in supporting precise item-specific working memory remains unclear.
Review
Neurosciences
Chris B. Martin, Morgan D. Barense
Summary: Perception and memory are not as separate as traditionally thought, as evidence shows early visual areas contribute to long-term recognition memory and medial temporal lobe structures contribute to high-level perceptual processing. A representational-hierarchical model that focuses on content differences rather than cognitive processes is proposed to better explain the empirical findings.
ANNUAL REVIEW OF VISION SCIENCE
(2023)
Article
Behavioral Sciences
Bohee Lee, June Sic Kim, Chun Kee Chung
Summary: Working memory is crucial for goal-directed behavior, and the frontoparietal network and medial temporal lobe play important roles in working memory. Through intracranial electroencephalography recording, it was found that low-frequency power in the frontal lobe and medial temporal lobe increased and sustained throughout the working memory task, while parietal alpha power peaked during memory operation. Furthermore, there was a positive correlation in the alpha band between the medial temporal lobe and the parietal lobe during memory operation.
Article
Biochemistry & Molecular Biology
Koji Koizumi, Naoto Kunii, Kazutaka Ueda, Keisuke Nagata, Shigeta Fujitani, Seijiro Shimada, Masayuki Nakao, Hua-Jun Feng
Summary: This study aimed to develop a neurofeedback (NF) system for the memory function of the medial temporal lobe (MTL) and examine changes in neural activity and memory task scores through NF training. The results showed promising potential for NF to modulate MTL activity and memory encoding. Further research is needed to improve the NF system and validate its effects on memory functions.
Article
Neurosciences
Shahin Tavakol, Qiongling Li, Jessica Royer, Reinder Vos de Wael, Sara Lariviere, Alex Lowe, Casey Paquola, Elizabeth Jefferies, Tom Hartley, Andrea Bernasconi, Neda Bernasconi, Jonathan Smallwood, Veronique Bohbot, Lorenzo Caciagli, Boris Bernhardt
Summary: This study introduces a new spatial memory paradigm and highlights an integrated structure-function substrate in the human temporal lobe. Through CSST task and MRI imaging methods, the research found that spatial memory performance is correlated with memory paradigm scores, but not with other types of memory.
Article
Neurosciences
Hendrik Heinbockel, Conny W. E. M. Quaedflieg, Till R. Schneider, Andreas K. Engel, Lars Schwabe
Summary: Acute stress may enhance theta oscillations in the medial temporal lobe during memory formation for emotionally negative stimuli. While the exact impact of stress on emotional memory remains unclear, it may aid in storing emotionally significant events in the context of a stressful encounter.
NEUROBIOLOGY OF STRESS
(2021)
Article
Clinical Neurology
Yuanzhi Xu, Ahmed Mohyeldin, Maximiliano Alberto Nunez, Ayoze Doniz-Gonzalez, Vera Vigo, Aaron A. Cohen-Gadol, Juan C. Fernandez-Miranda
Summary: The authors investigated the microvascular anatomy of the hippocampus and its implications for medial temporal tumor surgery, revealing the anatomical variability of the arterial supply and venous drainage of the hippocampus. The study found rich anastomoses between hippocampal arteries and highlighted the importance of understanding the vascular variability and network of the hippocampus for surgery in this region, including anterior temporal lobectomy with amygdalohippocampectomy and transsylvian selective amygdalohippocampectomy.
JOURNAL OF NEUROSURGERY
(2021)
Article
Behavioral Sciences
Domile Tautvydaite, Alexandra Adam-Darque, Aurelie L. Manuel, Radek Ptak, Armin Schnider
Summary: This study found that encoding of information begins before it is recognized, and recognition-related brain activity occurs during later repetitions.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2021)
Article
Behavioral Sciences
Hsiao-Wei Tu, Rachel A. Diana
Summary: In this study, by modifying the experimental paradigm and removing visual cues and condition-specific blocking, the results indicate that unitized context details are processed independently, contrary to previous findings. Neuroimaging data show anterior hippocampal activation is associated with unitization of context details, suggesting different cognitive processing for unitization versus relational encoding. Additionally, unitization of color information leads to increased bilateral perirhinal cortex activation and decreased parahippocampal cortex activation.
BEHAVIOURAL BRAIN RESEARCH
(2021)
Article
Medicine, General & Internal
Xiao-Ming Yan, Cui-Ping Xu, Yu-Ping Wang, Kai Ma, Tao Yu, Xiao-Hua Zhang, Xi Zhang, Run-Shi Gao, Guo-Jun Zhang, Yong-Jie Li
Summary: Patients with medial temporal lobe seizures had more favorable surgical outcomes and distinct SEEG features compared to patients with lateral temporal lobe seizures.
CHINESE MEDICAL JOURNAL
(2021)
Review
Clinical Neurology
Nadim Jaafar, Amar Bhatt, Alexandra Eid, Mohamad Z. Koubeissi
Summary: Some surgical failures after temporal lobe epilepsy surgery may be caused by the presence of extratemporal epileptogenic zones, particularly in the medial parietal lobe. Seizures originating from this area may not cause obvious symptoms before spreading to the temporal lobe.
FRONTIERS IN NEUROLOGY
(2022)
Article
Behavioral Sciences
Aubrey A. Wank, Anna Robertson, Sean C. Thayer, Mieke Verfaellie, Steven Z. Rapcsak, Matthew D. Grilli
Summary: Autobiographical memory consists of different types of memory, ranging from abstract to episodic. Self trait knowledge relies on specific regions of the autobiographical memory network, not the medial temporal lobes. This case study reveals a rare amnesia case with impaired self trait knowledge but preserved conceptual knowledge for personality traits and the ability to accurately evaluate others' traits.
Article
Geriatrics & Gerontology
Lea Chauveau, Elizabeth Kuhn, Cassandre Palix, Francesca Felisatti, Valentin Ourry, Vincent de La Sayette, Gael Chetelat, Robin de Flores
Summary: Studying the subregions of the medial temporal lobe is crucial for distinguishing age-related changes from Alzheimer's disease, with the findings highlighting the significant role of these subregions in cognitive functioning.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Neurosciences
Robin de Flores, Sandhitsu R. Das, Long Xie, Laura E. M. Wisse, Xueying Lyu, Preya Shah, Paul A. Yushkevich, David A. Wolk
Summary: This study reveals the relationship between the medial temporal lobe and the anterior-temporal and posterior-medial networks, and explores the vulnerability of these networks to proteinopathies in Alzheimer's disease. The results show that the atrophy of distinct subregions in the medial temporal lobe propagates differently within the anterior-temporal and posterior-medial networks. Additionally, these networks are differentially associated with relative tau and amyloid burden.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Clinical Neurology
Paul A. Yushkevich, Monica Munoz Lopez, Maria Mercedes Iniguez de Onzono Martin, Ranjit Ittyerah, Sydney Lim, Sadhana Ravikumar, Madigan L. Bedard, Stephen Pickup, Weixia Liu, Jiancong Wang, Ling Yu Hung, Jade Lasserve, Nicolas Vergnet, Long Xie, Mengjin Dong, Salena Cui, Lauren McCollum, John L. Robinson, Theresa Schuck, Robin de Flores, Murray Grossman, M. Dylan Tisdall, Karthik Prabhakaran, Gabor Mizsei, Sandhitsu R. Das, Emilio Artacho-Perula, Mari'a Del Mar Arroyo Jimenez, Mari'a Pilar Marcos Raba, Francisco Javier Molina Romero, Sandra Cebada Sanchez, Jose Carlos Delgado Gonzalez, Carlos De la Rosa-Prieto, Marta Corcoles Parada, Edward B. Lee, John Q. Trojanowski, Daniel T. Ohm, Laura E. M. Wisse, David A. Wolk, David J. Irwin, Ricardo Insausti
Summary: This study utilized ex vivo MRI and dense serial histological imaging to construct three-dimensional quantitative maps of neurofibrillary tangle burden in the medial temporal lobe, revealing significant variation along different anatomical regions. The findings provide valuable insights into the distribution of this neurodegenerative pathology and may support the development and validation of neuroimaging biomarkers.
