Article
Pediatrics
Federica Attaianese, Andrea Costantino, Cristiana Benucci, Donatella Lasagni, Sandra Trapani
Summary: Benign acute childhood myositis (BACM) is a self-limiting childhood illness mainly caused by viral infections. Clinical and laboratory features were characterized in a retrospective study, revealing bilateral calf pain, asthenia, and refuse to walk as common symptoms. Rapid resolution of complaints and normalization of biochemical markers can prevent unnecessary tests and therapies.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Pediatrics
A. Costa Azevedo, A. Costa e Silva, C. Juliana Silva, S. Poco Miranda, M. Costa, I Martinho
Summary: Benign acute childhood myositis (BACM) is a rare, self-limited inflammatory condition of the skeletal muscle that usually occurs after a viral infection. It mainly affects male and school-aged children, with typical symptoms including fever, cough, rhinorrhea, and bilateral calf pain. Hematological findings often show leukopenia and thrombocytopenia. Treatment primarily involves analgesia, rest, and hydration, and the prognosis is excellent.
ARCHIVES DE PEDIATRIE
(2022)
Article
Medicine, General & Internal
Ayse Secil Eksioglu, Ayla Akca Caglar, Seda Kaynak Sahap, Can Demir Karacan, Nilden Tuygun
Summary: The study demonstrates the high diagnostic value of sonoelastography in evaluating benign acute childhood myositis, providing accurate assessment of cases and aiding in follow-up processes.
TURKISH JOURNAL OF MEDICAL SCIENCES
(2021)
Article
Clinical Neurology
Emine Tekin, Handan Ayhan Akoglu
Summary: This study presented the etiological evaluation results of acute benign childhood myositis cases, with walking difficulty and tender gastrocnemius muscles being the most common complaints. Influenza A and B were found to be the most common causes, and timely treatment resulted in resolution of symptoms and normalization of biochemical markers to prevent unnecessary tests. Endemic and pandemic infections may also lead to this condition.
ACTA NEUROLOGICA BELGICA
(2022)
Article
Pediatrics
Caner Turan, Ali Yurtseven, Candan Cicek, Gulsum Keskin, Eylem Ulas Saz
Summary: The study aimed to investigate the association between benign acute childhood myositis (BACM) and respiratory viruses, and found that rhabdomyolysis caused by influenza A virus was more common in BACM. The study also found that early use of oseltamivir treatment was significantly associated with a shorter recovery time.
JOURNAL OF PAEDIATRICS AND CHILD HEALTH
(2022)
Article
Clinical Neurology
Silvia D'Amico, Gloria Gangi, Massimo Barbagallo, Toni Palermo, Maria Carla Finocchiaro, Antonella Distefano, Raffaele Falsaperla, Silvia Marino, Filippo Greco, Pierluigi Smilari, Piero Pavone
Summary: Benign acute childhood myositis (BACM) is a transient condition mainly affecting school-age children, characterized by muscle pain localized to the calf muscle with symmetrical lower extremity pain and difficulty in walking. It is usually preceded by viral infections and presents with fever and upper respiratory symptoms. The prognosis is generally good, with gradual improvement of symptoms and no reported recurrences or sequelae.
Article
Medicine, General & Internal
Alexis Hyczko, Mary Katherine Rohrbaugh, Alawia K. Suliman, Nicole M. Hackman
Summary: Benign acute childhood myositis is a relatively uncommon complication of viral illness, particularly influenza A and B infections. It has a self-limiting nature with excellent prognosis, symptoms gradually resolve following supportive management, and extensive laboratory evaluation and hospitalization are often unnecessary.
SAGE OPEN MEDICAL CASE REPORTS
(2021)
Article
Pediatrics
Betul Ozturk, Aytac Goktug, Ilknur Bodur, Raziye Merve Yaradilmis, Muhammed Mustafa Guneylioglu, Ali Gungor, Aysun Tekeli, Ayla Akca Caglar, Can Demir Karacan, Nilden Tuygun
Summary: This study found that the symptom resolution time was shorter in influenza-positive patients with BACM compared to influenza-negative patients, and oseltamivir treatment did not affect the duration of symptoms. Most children had normal blood indicators, and there were rare reports of clinical recurrence and metabolic diseases.
PEDIATRICS INTERNATIONAL
(2022)
Article
Public, Environmental & Occupational Health
P. Pari, E. Manikandan, Priya Jose, Peter Prasanth K. Kumar, Sharmila Fermendenz, Rahul Dhodapkar
Summary: Influenza virus primarily targets ciliated cells of the respiratory epithelium, and humans are vulnerable to infection due to lack of innate immunity. Benign acute childhood myositis often occurs during the early recovery phase of influenza, presenting with fever, cough, muscle pain, and nasal discharge.
Review
Pediatrics
Ilknur Kaba, Havva Nur Peltek Kendirci, Samet Can Demirbas
Summary: This study revealed the characteristics of benign acute myositis of childhood (CABM), finding that it occurs more frequently in boys than girls and that the serum CK level significantly decreases on the 4th day of admission. Despite the sudden and rapid initial symptoms, it should be recognized as a benign condition that recovers naturally and quickly.
GUNCEL PEDIATRI-JOURNAL OF CURRENT PEDIATRICS
(2022)
Article
Medicine, General & Internal
Yuki Takebuchi, Airi Minatogawa, Yumi Naito, Chiaki Sano, Ryuichi Ohta
Summary: Hypereosinophilic syndrome is a disease with various symptoms caused by abnormal rise of eosinophils in blood and infiltration into organs. Diagnosis may be difficult due to its self-limiting phases and rare concomitant symptoms. This case highlights the exacerbation of chronic hypereosinophilia with acute symptoms and emphasizes the importance of prompt examination and treatment based on involved organs.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Review
Pediatrics
Gabriel Bronz, Danilo Consolascio, Mario G. Bianchetti, Pietro O. Rinoldi, Celine Betti, Sebastiano A. G. Lava, Gregorio P. Milani
Summary: This study systematically investigated the Kobner and Pastia signs in acute hemorrhagic edema and found that these signs occur in about every fourth child with this condition, without influencing disease progression.
Review
Pharmacology & Pharmacy
Arianna Piffer, Mario G. Bianchetti, Corinna Leoni-Foglia, Giacomo D. Simonetti, Gregorio P. Milani, Sebastiano A. G. Lava
Summary: The use of vaptans in children for the treatment of oedematous and hyponatraemic disorders appears to be safe and effective, showing an increase in diuresis and sodium levels. However, no superiority over traditional treatment methods has been demonstrated.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
Review
Pediatrics
Valentina M. L. Montorfani-Janett, Gabriele E. Montorfani, Camilla Lavagno, Gianluca Gualco, Mario G. Bianchetti, Gregorio P. Milani, Sebastiano A. G. Lava, Marirosa Cristallo Lacalamita
Summary: The involvement of external male genitalia in Henoch-Schonlein vasculitis is not well categorized. This systematic review analyzed 85 reports and found that the genital involvement mostly appeared concurrently with or after the cutaneous features of Henoch-Schonlein syndrome. Scrotal involvement can result from skin inflammation, epididymitis, orchitis, or testicular ischemia.
Article
Infectious Diseases
Gabriel Bronz, Benedetto P. E. S. M. Zanetti, Mario G. Bianchetti, Gregorio P. Milani, Sebastiano A. G. Lava, Thomas J. Neuhaus, Anne Witschi, Lisa Kottanattu
Summary: Epstein-Barr virus infectious mononucleosis typically presents with various symptoms, and the presence of Hoagland sign, a rarely mentioned clinical sign, may provide early diagnostic value.
Review
Infectious Diseases
Pietro B. Fare, Erica Memoli, Giorgio Treglia, Mario G. Bianchetti, Gregorio P. Milani, Paola Marchisio, Sebastiano A. G. Lava, Simone Janett
Summary: This study summarizes the prevalence and factors associated with trimethoprim-induced hyperkalaemia. The results indicate that the occurrence of trimethoprim-associated hyperkalaemia is dose-related and influenced by concurrent administration of hyperkalaemic drugs and poor kidney function.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2022)
Review
Immunology
Gabriel Bronz, Pietro B. Fare, Sebastiano A. G. Lava, Mario G. Bianchetti, Giacomo D. Simonetti, Martin Scoglio, Benedetta Terziroli Beretta-Piccoli, Carlo Agostoni, Gregorio P. Milani
Summary: COVID-19 and SARS-CoV-2 vaccination may have an impact on immunoglobulin A-mediated diseases. Berger glomerulonephritis is mostly associated with vaccination, while Henoch-Schonlein vasculitis is mainly associated with infection. mRNA-based vaccines are often implicated in vaccine-associated immunoglobulin A diseases.
JOURNAL OF AUTOIMMUNITY
(2022)
Article
Cardiac & Cardiovascular Systems
Lucrezia Pusterla, Dragana Radovanovic, Franco Muggli, Paul Erne, Andreas W. Schoenenberger, Renate Schoenenberger-Berzins, Gianfranco Parati, Paolo Suter, Sebastiano A. G. Lava, Augusto Gallino, Mario G. Bianchetti
Summary: Arterial stiffness is an important predictor of cardiovascular risk, in addition to traditional risk factors. This study investigated the relationship between arterial stiffness and traditional cardiovascular risk factors as well as sex in a rural population in Southern Switzerland. The findings suggest that aortic pulse wave velocity, an indicator of arterial stiffness, is associated with age, sex, blood pressure, and heart rate.
CARDIOLOGY AND THERAPY
(2022)
Article
Pediatrics
Stefano C. Di Bernardo, Sebastiano A. G. Lava, Adina Mihaela Epure, Sandrine Estoppey Younes, Arnaud Chiolero, Nicole Sekarski
Summary: This study aimed to assess the effect of maternal gestational diabetes (GDM) on offsprings' cardiovascular health. The results showed that infants of mothers with GDM had some echocardiographic differences, suggesting altered myocardial physiology among these infants.
PEDIATRIC RESEARCH
(2023)
Article
Nutrition & Dietetics
Lisa Ponti, Luca Gabutti, Pietro B. Fare, Simone Janett, Mario G. Bianchetti, Peter J. Schulz, Sebastiano A. G. Lava, Carlo Agostoni, Gregorio P. Milani
Summary: This report investigates the daily vitamin D supply provided by multivitamins containing vitamin D sold on Amazon marketplaces in Western and Southern Europe. The study found that most multivitamins had insufficient vitamin D-3 supply, and only a few products met the recommended dosage for high-risk individuals.
Review
Medicine, General & Internal
Gwendolyn Graf, Giulia A. M. Vassalli, Lisa Kottanattu, Mario G. Bianchetti, Carlo Agostoni, Gregorio P. Milani, Sebastiano A. G. Lava, Pietro B. Fare, Simone Janett
Summary: This study provides a systematic review on acute pancreatitis associated with atypical pneumonia, and identifies the association with Mycoplasma pneumoniae, Legionella species, and Coxiella burnetii.
JOURNAL OF CLINICAL MEDICINE
(2022)
Editorial Material
Pediatrics
Sebastiano A. G. Lava
Editorial Material
Pediatrics
Sebastiano A. G. Lava
Review
Medicine, General & Internal
Monica C. M. Bischof, Mariana I. E. Stadelmann, Simone Janett, Mario G. Bianchetti, Pietro Camozzi, Barbara Goeggel Simonetti, Sebastiano A. G. Lava, Gregorio P. Milani
Summary: Long-term medication with valproic acid is associated with acute pancreatitis. This study investigated the features of this pancreatitis and found that approximately 84% of patients recovered and 16% died within 11 months of starting valproic acid. Among patients rechallenged with valproic acid, about 84% developed a further episode of pancreatitis.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Pediatrics
Sebastiano A. G. Lava, Chiara Zollinger, Hassib Chehade, Damien Schaffner, Nicole Sekarski, Stefano Di Bernardo
Summary: Diuretics are commonly used drugs for managing various pathological conditions. This article provides an overview of their indications, mechanisms of action, side effects, pharmacokinetics considerations, and data in children. It also briefly addresses newer diuretic classes, controversies on hydrochlorothiazide, and diuretic resistance.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Review
Allergy
Gabriel Bronz, Celine Betti, Pietro O. Rinoldi, Lisa Kottanattu, Mario G. Bianchetti, Danilo Consolascio, Marcel M. Bergmann, Gregorio P. Milani, Benedetta Terziroli Beretta Piccoli, Sebastiano A. G. Lava
Summary: Finkelstein-Seidlmayer vasculitis is mostly preceded by infection and occasionally by vaccination. In most cases, the vasculitis develops after the resolution of the infection, but in some cases, it occurs before the resolution of the infection.
CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
(2022)