Review
Anesthesiology
Nasir Hussain, Jatinder Gill, Jarod Speer, Mahmoud Abdel-Rasoul, Alaa Abd-Elsayed, Safdar Khan, Anthony Nguyen, Thomas Simopoulos, Tristan Weaver
Summary: This study evaluated the incidence of spinal cord injury after spinal cord stimulator implant using a large-scale claims database. The results showed that spinal cord stimulator implant continues to be a safe procedure for chronic pain patients. However, risk factor mitigation strategies should be undertaken prior to performing the procedure in order to prevent spinal cord injury.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2022)
Article
Chemistry, Multidisciplinary
Dingchang Lin, Jung Min Lee, Chonghe Wang, Hong-Gyu Park, Charles M. M. Lieber
Summary: Spinal cord neuromodulation can restore partial to complete loss of motor functions associated with neuromotor disease and trauma. A flexible and stretchable spinal stimulator design with nanoscale thickness has been developed to target the ventral spinal space of mice through minimally invasive injection. This approach holds translational potential for improving controllable limb function following spinal cord injury or neuromotor disease.
Article
Medicine, Research & Experimental
Gene Tekmyster, Holly Jonely, David W. Lee, Jason Myerson, Melinda Avery, Maxim Moradian, Mehul J. Desai
Summary: Spinal cord stimulation (SCS) is an established therapy option in interventional pain medicine, and recent advances in technology have improved compliance and efficacy in pain control. However, there is a lack of consensus on physical therapy considerations for patients with SCS implants. This study proposes standardized rehabilitative care for this population and highlights the need for further research in the field.
Article
Anesthesiology
Vasudha Goel, Alexander M. Kaizer, Sejal Jain, David Darrow, Hariharan Shankar
Summary: This study uses a large administrative claims database to determine the 30-day risk of spinal cord injury after spinal cord stimulation implantation surgery. It suggests that intraoperative neurophysiological monitoring can help mitigate the risk of spinal cord injury and further research is needed for risk mitigation.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Article
Chemistry, Multidisciplinary
Bruce Harland, Zaid Aqrawe, Maria Vomero, Christian Boehler, Ernest Cheah, Brad Raos, Maria Asplund, Simon J. O'Carroll, Darren Svirskis
Summary: This study presents the development of a very thin flexible bioelectronic implant that can be inserted directly into the spinal cord of rats and maintain contact. The implant does not negatively impact the functionality of the rats' limbs and can record electrical signals of spinal cord activity. This device is important for monitoring spinal cord injury and recovery, and has the potential for localized treatments.
Article
Anesthesiology
Cormac Francis Mullins, Jonathan Royds, Adnan Al-Kaisy
Summary: This study examined the occurrence and factors associated with radiographic lead migration during percutaneous SCS trials and found that 50% of leads experienced significant migration. However, this migration was not found to impact trial success.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Article
Anesthesiology
Vasudha Goel, Varun Kumar, Amol M. Patwardhan, Mohab Ibrahim, Eellan Sivanesan, David Darrow, Hariharan Shankar
Summary: The study finds that the 30-day readmission rate after SCS implantation is approximately 7.7% in the United States. Infection and postoperative complications are still the top etiologies for readmissions. Compared to percutaneous SCS implantation procedures, open surgical SCS implantation is associated with more extended initial hospitalization and a higher rate of readmission.
ANESTHESIA AND ANALGESIA
(2022)
Article
Chemistry, Analytical
Seunghyeon Yun, Chin Su Koh, Jungmin Seo, Shinyong Shim, Minkyung Park, Hyun Ho Jung, Kyungsik Eom, Jin Woo Chang, Sung June Kim
Summary: This article describes a fully implantable miniaturized spinal cord stimulator based on a biocompatible liquid crystal polymer (LCP). The stimulator suppresses pain signals by electrically stimulating the spinal cord. Compared to traditional metal packaged and battery-operated stimulators, this LCP-based device is smaller and lighter, allows wireless power and data transfer, and has shown effective pain suppression in animal models.
Article
Obstetrics & Gynecology
Douglas Luchristt, David Sheyn, C. Emi Bretschneider
Summary: The objective of this analysis was to provide national estimates of rates and patterns of labiaplasty performance among all payers in the ambulatory surgery setting. The study found that the highest rate of labiaplasty cases occurred among adolescent and young women in the United States, with nearly 20% of all cases being performed in girls younger than age 18 years. Given the limited outcome data and potential long-term adverse events associated with this procedure, as well as the high rate of minors undergoing this procedure, more dedicated research assessing the prevalence and associated outcomes is warranted.
OBSTETRICS AND GYNECOLOGY
(2022)
Article
Clinical Neurology
David Stolzenberg, Junyoung J. Ahn, Mayan Lendner, Mark Kurd
Summary: Spinal cord stimulator trials are suitable for treating postlaminectomy syndrome and refractory complex regional pain syndrome. The article provides detailed instructions on patient positioning, setup, procedural steps, and postoperative care, along with discussions on pearls and pitfalls. Additionally, a supplemental instructional video is included.
CLINICAL SPINE SURGERY
(2021)
Article
Medicine, Research & Experimental
Tessa A. Harland, Gregory Topp, Kevin Shao, Julie G. Pilitsis
Summary: This study characterizes the safety profile of SCS paddle replacement surgeries. The results show that replacing paddle leads at the time of removal, with additional lamina removal if needed because of scar tissue, is associated with low rates of complications.
Article
Anesthesiology
Devin D. Antonovich, Willy Gama, Alexandra Ritter, Bethany Jacobs Wolf, Ryan H. Nobles, Meron A. Selassie, M. Gabriel Hillegass
Summary: The study found that reoperation rates and time to reoperation between percutaneous and paddle leads in spinal cord stimulation systems are clinically similar, with younger age at the time of placement being the only factor associated with the risk of reoperation.
Article
Clinical Neurology
Steve H. Monk, Matthew O'Brien, Joe D. Bernard, Paul K. Kim
Summary: This study aimed to demonstrate the feasibility and safety of thoracic paddle lead implantation in an ambulatory surgery center. The results showed that the complication rates were comparable to the hospital setting. Further research is needed to evaluate the clinical outcomes and cost-effectiveness of ambulatory surgery.
WORLD NEUROSURGERY
(2023)
Review
Engineering, Biomedical
Steven M. Falowski, Hao Tan, Joseph Parks, Alaa Abd-Elsayed, Ahmed Raslan, Jason Pope
Summary: This comprehensive literature review evaluates the most common complications encountered with spinal cord stimulation (SCS) implantation. The authors suggest strategies to avoid and treat these complications, including appropriate patient selection, adherence to evidence-based guidelines, and best practice recommendations.
EXPERT REVIEW OF MEDICAL DEVICES
(2023)
Article
Neurosciences
S. E. Mondello, B. D. Pedigo, M. D. Sunshine, A. E. Fischedick, P. J. Horner, C. T. Moritz
Summary: This study introduces a long-term implantable mu LED device for optogenetic stimulation of the spinal cord in awake, freely moving rats. The device is simple enough to be fabricated, implanted, and operated by most laboratories, inducing robust movements without causing physical or thermal damage to the spinal cord for at least 6 weeks. This mu LED device could help unravel the complexities of the spinal cord and uncover potential future therapeutic options.
EXPERIMENTAL NEUROLOGY
(2021)
