Intrathecal delivery of farnesyl thiosalicylic acid and GW 5074 attenuates hyperalgesia and allodynia in chronic constriction injury-induced neuropathic pain in rats

Therapeutic Targets for the Management of Peripheral Nerve Injury- Induced Neuropathic Pain

(2012) Amteshwar Singh Jaggi et al.   CNS & Neurological Disorders-Drug Targets

A new approach to Parkinson's disease: inhibition of leucine-rich repeat kinase-2

(2011) Sheila A Doggrell   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Inhibitors of LRRK2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson's disease models

(2011) Zhaohui Liu et al.   HUMAN MOLECULAR GENETICS

Mechanisms in cancer-chemotherapeutic drugs-induced peripheral neuropathy

(2011) Amteshwar Singh Jaggi et al.   TOXICOLOGY

Sustained morphine-mediated pain sensitization and antinociceptive tolerance are blocked by intrathecal treatment with Raf-1-selective siRNA

(2010) S Tumati et al.   BRITISH JOURNAL OF PHARMACOLOGY

Differential effect of spironolactone in chronic constriction injury and vincristine-induced neuropathic pain in rats

(2010) Amteshwar Singh Jaggi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Animal models of neuropathic pain

(2010) Amteshwar Singh Jaggi et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

The combined treatment of Copaxone and Salirasib attenuates experimental autoimmune encephalomyelitis (EAE) in mice

(2010) Elizabeta Aizman et al.   JOURNAL OF NEUROIMMUNOLOGY

Characterization of Fasudil in Preclinical Models of Pain

(2010) Janel M. Boyce-Rustay et al.   JOURNAL OF PAIN

Mammalian target of rapamycin in spinal cord neurons mediates hypersensitivity induced by peripheral inflammation

(2010) E. Norsted Gregory et al.   NEUROSCIENCE

RhoA/Rho kinase pathway contributes to the pathogenesis of thermal hyperalgesia in diabetic mice

(2010) Masahiro Ohsawa et al.   PAIN

Inhibition of the Rho/ROCK pathway prevents neuronal degeneration in vitro and in vivo following methylmercury exposure

(2010) Masatake Fujimura et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Sustained Morphine Treatment Augments Capsaicin-Evoked Calcitonin Gene-Related Peptide Release from Primary Sensory Neurons in a Protein Kinase A- and Raf-1-Dependent Manner

(2009) S. Tumati et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Intrathecal Raf-1-selective siRNA attenuates sustained morphine-mediated thermal hyperalgesia

(2008) Suneeta Tumati et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Sustained morphine treatment augments basal CGRP release from cultured primary sensory neurons in a Raf-1 dependent manner

(2008) Xu Yue et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ameliorative effects of amiloride and pralidoxime in chronic constriction injury and vincristine induced painful neuropathy in rats

(2008) Arunachalam Muthuraman et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Inhibition of ATF-3 expression by B-Raf mediates the neuroprotective action of GW5074

(2008) Hsin-Mei Chen et al.   JOURNAL OF NEUROCHEMISTRY

Salirasib (farnesyl thiosalicylic acid) for brain tumor treatment: a convection-enhanced drug delivery study in rats

(2008) L. Goldberg et al.   MOLECULAR CANCER THERAPEUTICS

Raf inhibition protects cortical cells against β-amyloid toxicity

(2008) Valentina Echeverria et al.   NEUROSCIENCE LETTERS

Axonal accumulation of hyperpolarization-activated cyclic nucleotide-gated cation channels contributes to mechanical allodynia after peripheral nerve injury in rat

(2008) Yu-Qiu Jiang et al.   PAIN

Inhibitors of Chronically Active Ras: Potential for Treatment of Human Malignancies

(2008) Yoel Kloog et al.   Recent Patents on Anti-Cancer Drug Discovery

Changes in cardiovascular parameters and plasma norepinephrine level in rats after chronic constriction injury on the sciatic nerve

(2007) Yu Jin et al.   PAIN